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抗凝和促凝血的之间的区别

August 3, 2019Posted byDr.Samanthi

Thekey differencebetween procoagulant and anticoagulant is thatprocoagulant is a substance that is necessary for bloodcoagulation, while anticoagulant is a substance that prevents blood coagulation.

Blood coagulation plays a vital role during an injury or a cut of a blood vessel. It prevents the excessive loss of blood from the blood system before leading to shock or death. At the site of injury, blood coagulation process produces a blood clot using platelets and clotting factors. Therefore, a blood clot consists of a plug ofplatelets和一个不溶性纤维蛋白分子网络。纤维蛋白是一种不溶性,纤维和非 -globular proteinwhich involves in the clotting of blood. It is the underlying fabric polymer of a blood clot. Procoagulants mediate blood coagulation while anticoagulants prevent blood coagulation. Haemostasis depends on the balance between procoagulants and anticoagulants.

内容

1.Overview and Key Difference
2.What is Procoagulant
3.What is Anticoagulant
4.Similarities Between Procoagulant and Anticoagulant
5.并排比较 - 表格形式的Procagulant vs抗凝剂
6.概括

什么是procogulant?

Procoagulant is a substance that is necessary for the coagulation of blood. In fact, procoagulants are precursors of various blood factors. Hence, they promote blood coagulation.

抗凝和促凝血的之间的区别

图01:Procagulant - 凝血酶

Thrombin and factor Xa are two procoagulants. Thus, procoagulants are hemostatic agents. They have the ability to seal severe injuries very quickly, before leading to complications.

What is an Anticoagulant?

顾名思义,抗凝剂是一种针对凝血过程的物质。简而言之,抗凝剂是防止血液凝血的物质。因此,这些物质阻止了血凝块的形成。抗凝药是医疗个人针对中风和心脏病发作风险较高的患者处方的鲜血药物,因为不必要的血凝块可以阻止血管,并且可以阻止血液流向大脑,肺和心脏等重要器官,等等。

Key Difference - Procoagulant vs Anticoagulant

Figure 02: Anticoagulant – Warfarin

Warfarin is the most commonly used anticoagulant medicine. Rivaroxaban, dabigatran, apixaban and edoxaban are newer types of anticoagulant medicines.

What are the Similarities Between Procoagulant and Anticoagulant?

  • 凝血和抗凝剂是与血液凝血有关的物质。
  • Their reactions play an important role in the regulation of thrombin formation during secondary hemostasis.
  • Under normal physiological conditions, there is a delicate balance between procoagulant and anticoagulant reactions.

What is the Difference Between Procoagulant and Anticoagulant?

Procoagulant is a precursor that promotes blood coagulation. In contrast, an anticoagulant is a substance that prevents blood coagulation. So, this is the key difference between procoagulant and anticoagulant. Furthermore, procoagulants are medications that use to seal severe injuries before leading to complications while anticoagulants are blood-thinning medicines that prevent the formation of blood clots in patients that have a higher risk of strokes and heart attacks. Therefore, we can consider this too as a difference between procoagulant and anticoagulant.

抗凝和促凝血的之间的区别in Tabular Form

概括– Procoagulant vs Anticoagulant

Procoagulant and anticoagulants are two types of substances that work opposite to each other. Procoagulant promotes blood coagulation, while anticoagulant prevents blood coagulation. Therefore, this is the key difference between procoagulant and anticoagulant. Procoagulants are important when sealing severe injuries, while anticoagulants are important when stopping blood clot formation in patients that show a higher risk of strokes and heart attacks.

Reference:

1. “Anticoagulant medicines.” NHS Choices, NHS,Available here.
2. “Coagulation.” Wikipedia, Wikimedia Foundation, 23 July 2019,Available here.

Image Courtesy:

1. “thrombin” ByRichard Grant(CC BY-SA 2.0)viaFlickr
2. “Warfarin” By Calvero – Selfmade with ChemDraw (Public Domain) viaCommons Wikimedia

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Filed Under:Biochemistry

About the Author:Dr.Samanthi

Samanthi Udayangani博士拥有B.Sc.植物科学学位,硕士在分子和应用微生物学和应用微生物学中的博士学位。她的研究兴趣包括生物肥料,植物 - 微生物相互作用,分子微生物学,土壤真菌和真菌生态学。

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