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之间的区别纳德+纳德H and NADPH

2013年9月23日发表Samanthi博士

这钥匙区别在NAD之间+NADH和NADPH取决于它们存在的形式。纳德+is in the oxidized form while NADH is in the reduced form. On the other hand, NADPH is a reducing agent that has an additionalphosphate groupthan NADH。

Nicotinamide Adenine Dinucleotide (NAD+)是辅酶存在于生物系统中。NADH是NAD的减少形式+。烟酰胺腺嘌呤二核苷酸磷酸盐(NADPH)也是辅助酶,涉及合成代谢反应。它是脂质和核酸合成中的还原剂。所有这些nad+,NADH和NADPH是生物反应中的重要共同因素。他们在酶催化中起着至关重要的作用代谢反应作为电子载体。本文的目的是讨论NAD之间的区别+纳德和纳德。

CONTENTS

1。概述和关键差异
2。什么是nad+
3。什么是纳德
4。什么是nadph
5。Similarities Between NAD+ NADH and NADPH
5。并排比较 - nad+ vs nadh vs nadph以表格形式
6.Summary

什么是nad+?

Nicotinamide Adenine Dinucleotide (NAD+)是共生酶。它具有维生素B骨架。因此,它是水溶性化合物。纳德+mainly involves redox reactions. As it is positively charged, it can act as an oxidizing agent. It oxidizes other compounds and converts to its reduced form which is NADH.

NAD+,NADH和NADPH之间的差异

图01:NAD+氧化和还原

纳德+is used in many enzyme-catalyzed reactions, especially in the electron transfer during cellular respiration. Synthesis of NAD+takes place via a denovo pathway using the starting compounds aspartate and tryptophan. Also, synthesis also takes place through modification of niacin which is taken from the diet. Therefore, it is important to have a balanced diet to maintain the levels of NAD+in the body.

纳德是什么?

NADH是NAD的减少形式+。它也是辅酶。它可以用作还原剂并自身氧化,同时还原其他化合物。因此,NADH在许多分解代谢反应中作为电子载体很有用。此外,NADH在柠檬酸周期中充当辅酶。

NADH还充当许多酶(例如酒精脱氢酶等)的共同因素。此外,NADH具有肝保护活性,并在降低胆固醇和血压中起作用。

NAD+,NADH和NADPH之间的差异_Figure 2

Figure 02: NADH

NADH的合成也类似于NAD+。Thus, same starting compounds; aspartate and tryptophan involve in the synthesis of NADH. Also, niacin or vitamin B is also involved in the synthesis of NADH.

什么是nadph?

NADPH代表烟酰胺腺嘌呤二核苷酸磷酸盐。顾名思义,除了NADH的化学成分外,NADPH中还有一个额外的磷酸组。它是一种辅酶,在大多数反应中主要是合成代谢反应中的还原剂。此外,它在脂质代谢和核酸代谢中起着重要作用。

Key Difference Between NAD+, NADH and NADPH

图03:nadph

NADPH的合成或产生主要是通过五磷酸五磷酸途径进行的。同样,NADPH是通过使用NADH激酶的酶反应合成的。在线粒体中,NADH激酶将NADH转化为NADPH。在植物中,NADPH形成发生在光合作用的光反应期间。

NAD之间有什么相似之处+纳德和纳德?

  • 纳德+,NADH和NADPH是辅酶。
  • 而且,它们充当代谢反应中的电子载体。
  • 而且,它们是维生素B3或烟酸或烟酰胺的衍生物。
  • 此外,他们参加了氧化还原反应。
  • 此外,它们对于调节体内的代谢反应很重要。

What is the Difference Between NAD+纳德和纳德?

纳德+NADH和NADPH是共酶的活细胞中的重要化合物。纳德+is the oxidized form of NADH while NADH is the reduced form of NAD+。NADPH也是一种辅酶,由于存在额外的磷酸基团而与NADH不同。因此,这是NAD之间的关键区别+纳德和纳德。而且,纳德+是一种氧化剂,而NADH和NADPH是还原剂。此外,纳德+NADPH参与合成代谢反应时,NADH正在参与分解代谢反应。因此,这是NAD之间的另一个区别+纳德和纳德。

A further difference between NAD+NADH和NADPH是色氨酸和天冬氨酸是NAD的起始化合物+NADH合成和NADPH合成通过戊糖磷酸盐途径发生。以下信息图提供了有关NAD差异的更多信息+纳德和纳德。

NAD+ NADH和NADPH以表格形式的差异

Summary – NAD+ vs NADH vs NADPH

纳德+纳德H and NADPH are coenzymes which participate in biological reactions. They are derivatives of vitamin B3 or niacin. They participate in redox reactions. In summary of the difference between NAD+纳德和纳德,纳德+以NADH的氧化形式,而NADH是NAD的还原形式+。纳德PH, on the other hand, consists of an additional phosphate group than NADH and generates through the pentose phosphate pathway. Furthermore, NAD+分解反应和NADH参与纳德PH involves in anabolic reactions. Also, NAD+是一种氧化剂,而NADH和NADPH是还原剂。

参考:

1. Ying,W。当前的神经病学和神经科学报告,美国国家医学图书馆,2008年2月。在这里可用

图片提供:

1。”NAD+ Oxidation and Reduction”By JacobShalk – Own work,(CC BY-SA 4.0)通过下议院维基梅迪亚
2. Neurotiker的“ NADH PHYS” - 自己的作品,(公共领域)通过下议院维基梅迪亚
3. tagm2a在法国Wikipedia的“ NADPH” - 通过下议院维基梅迪亚

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提交以下:生物化学

关于作者:Samanthi博士

Samanthi博士Udayangani holds a B.Sc. Degree in Plant Science, M.Sc. in Molecular and Applied Microbiology, and PhD in Applied Microbiology. Her research interests include Bio-fertilizers, Plant-Microbe Interactions, Molecular Microbiology, Soil Fungi, and Fungal Ecology.

Comments

  1. Jules105says

    2016年6月21日,上午2:56

    Should I buy NADH or NAD+ supplement for improved health and anti-aging? Is it true that NADH supplements are almost ineffective? Thank you.

    回复
    • 泰勒·乔丹says

      2018年9月19日上午3:03

      I’m not sure how effective those are as supplements, but increasing your niacin levels may help –
      make sure you get niacin, not a precursor, real niacin will cause ‘flushing’ of the skin. Look up flushing niacin on ebay or similar site. Avoid non-flushing as it likely cannot help your NAD levels.

      回复

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