Thekey differencebetween oxidases and oxygenases is thatthe oxidases are theenzymesthat catalyze theoxidation-reduction reactionsby transferring the hydrogen from a substrate to oxygen, and thus, forming water or hydrogen peroxide while, the oxygenases are the enzymes that catalyze direct incorporation of the oxygen from the molecular oxygen (O2) to asubstrateduring the oxidation of a particular substrate.
酶是蛋白质分子,可催化活生物体细胞中发生的生化反应。因此,它们通过减少反应的活化能来增加反应速率。因此,反应以高速发生。同样,一些酶会催化复杂分子的分解为其单体,而某些酶会催化其单体的生物分子形成。同样,氧化酶和氧酶是所有生物体中存在的两种类型的酶。
内容
1.Overview and Key Difference
2.What are Oxidases
3.What are Oxygenases
4.Similarities Between Oxidases and Oxygenases
5.Side by Side Comparison – Oxidases vs Oxygenases in Tabular Form
6.概括
氧化酶类是什么?
氧化酶是一种催化氧化还原反应的氧化还原酶。这些酶通过将氢从底物转移到氧气中参与氧化还原反应。然后氧成为水(H2O) or hydrogen peroxide (H2O2).
通常,氧化酶存在于人体的许多部位,它们充当氧化许多类型的底物的催化剂。结果,将许多复杂分子(如胺,葡萄糖和黄烷)氧化为更简单的分子,这些分子很容易被人体代谢。
Furthermore, there are different types of oxidases, and their names vary according to the molecule that they catalyze. Some examples of oxidases are cytochrome oxidase, ascorbic acid oxidase, uricase and monoamine oxidase. The following reaction illustrates the action of oxidase in an oxidation-reduction reaction,
啊 + o2+ 2H++ 2e- - - - - -= aoh + h2O
What are Oxygenases?
Oxygenases are a subgroup of oxido-reductases. These enzymes catalyze the incorporation of oxygen atoms from molecular O2to substrates during the oxidation of a substrate. Some reactions incorporate two oxygen atoms while some reactions incorporate one oxygen atom. Thus, based on the number of oxygen atoms incorporated during the reaction, the enzyme that catalyzes the reaction differs.
Mono-oxygenases catalyze the incorporation of one oxygen atom as a hydroxyl group to a substrate. The second oxygen atom involves in the making of water molecule. Some examples of monooxygenases are tryptophan pyrrolase and carotenase. On the other hand, dioxygenases catalyze the incorporation of two atoms of oxygen to a substrate. Some examples of dioxygenases are phenylalanine hydroxylase and tyrosinase.
The following reaction illustrates the catalysis of mono-oxygenase in an oxidation-reduction reaction,
AH + XH2+ O2= aoh + x + h2O
What are the Similarities Between Oxidases and Oxygenases?
- Both oxidases and oxygenases are proteins that work as biocatalysts.
- Furthermore, they are oxido-reductases that catalyze oxidation-reduction reactions.
氧化酶和氧酶之间有什么区别?
氧化酶和氧酶之间的关键差异是它们催化的氧化还原反应。氧化酶催化氢从底物转移到氧气,而氧化酶则催化原子氧气从O中催化2到基材。此外,氧酶有两种类型。单加氧酶和二氧酶,而氧化酶是一种。因此,这是氧化酶和氧酶之间的另一个区别。
Moreover, a further difference between oxidases and oxygenases is that the oxidases are generally found in cell membranes and are responsible for the building of ATP that store cell energy while oxygenases are responsible for breaking down iron that is distributed to the whole body.
以下信息图提供了有关氧化酶和氧酶之间差异的更多详细信息。
摘要 - 氧化酶与氧合酶
Oxidases and oxygenases are two types of oxido-reductases that catalyze oxidation-reduction reactions. Oxidases catalyze the transferred hydrogen from the substrate to an oxygen during the oxidation-reduction reaction. On the other hand, oxygenases catalyze the direct incorporation of the oxygen atoms from O2到基材。Therefore, this is the key difference between oxidases and oxygenases.
Reference:
1.“氧合酶。”。神经图像,学术出版社。Available here
Image Courtesy:
1.”Monoamine oxidase A 2BXS”By Fvasconcellos, De Colibus L, Li M, Binda C, Lustig A, Edmondson DE, Mattevi A (2005). “Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B”. Proc. Natl. Acad. Sci. U.S.A. 102 (36): 12684–9. PMID 16129825. doi:10.1073/pnas.0505975102., (Public Domain) viaCommons Wikimedia
2.”Reaction Tyrosinase”By Yikrazul – Own work, (Public Domain) viaCommons Wikimedia
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