Difference Between PAO2 and SAO2

Key Difference – PAO2 vs SAO2

The transport ofoxygen (O₂)by blood in thearteriesis a critical process and is governed by many factors such asphof the blood,partial pressuresof the gases in blood, saturation levels of O₂, concentration of available血红蛋白and cardiac efficiency. The balance of these factors will assure the efficient transport of O₂根据特定组织的需求来进行外围组织。O的部分压力和O的饱和度₂是两个非常重要的参数，这些参数决定了O的健康运输₂in blood that is characterized by the Oxygen-Hemoglobin dissociation curve which depicts the saturation of hemoglobin with O₂, the partial pressure and the concentration of O₂in blood.The partial pressure of O₂(PAO₂) is the pressure exerted by O₂在动脉壁上而O的饱和度₂(SAO₂) is the overall percentage of hemoglobin binding sites occupied by O_2.This is the key difference between PAO2 and SAO2_.

内容

1.Overview and Key Difference
2.What is PAO₂
3.What is SAO₂
4.Similarities Between PAO₂and SAO₂
5.Side by Side Comparison – PAO₂vs SAO₂以表格形式
6.概括

What is PAO₂?

部分压由道尔顿的部分压力定律定义，其中指出系统的总压力等于混合物中存在的气体所施加的个别压力的总和。通过假设允许血液与一定数量的气体平衡，可以测量血液中溶解气体的部分压力。因此，Partial Pressure of O₂(PAO₂) also known as theO₂tension in blood, is the pressure exerted by O₂on the arterial wall. It is important to note that O₂在血液中溶解在其他气体的混合物中carbon dioxide and carbon monoxide, but O₂is the only gas that exerts a pressure on the arterial wall.

When the concentration of O₂in the blood is higher, the PAO₂also rises, allowing the blood to carry higher amounts of O₂in comparison with other fluids such as water. Measuring and recording PAO₂is important during disease states because there are certain physiological processes that depend on changes in O₂在其微环境中，其特征是Pao的变化_2.

What is SAO₂?

O的饱和度₂(SAO₂) in blood defines the percentage of hemoglobin binding sites that are occupied by O_2.Each hemoglobin molecule can occupy four O₂molecules as it can allosterically modify its conformation to facilitate binding of O₂to its binding site. During 100% saturation, all hemoglobin binding sites are occupied by O_2,and any increase in partial pressure or the concentration of O₂in blood would not cause an increase in saturation. This is depicted by the plateau area of the oxygen-hemoglobin dissociation curve. This saturation pattern is the reason for the characteristic sigmoid shaped curve of the O₂– Hemoglobin curve.

What are the Similarities Between PAO₂and SAO₂?

• PAO₂and SAO₂depend on the concentration of O₂present in the blood and lungs.
• 这两个参数都可以用作暗示血红蛋白失衡的指标。_2,cardiac efficiency and respiratory efficiency.
• PAO₂and SAO₂are directly proportional until O₂达到其最大饱和度。

What is the Difference Between PAO₂and SAO₂?

PAO2vs SAO2
PAO2是由O施加的压力吗2on the arterial wall.	SAO2血红蛋白结合位点的比例是are occupied by O2.
表达单位
PAO2is expressed in Pascal (pressure measuring units).	SAO2is expressed as a percentage.
Depending Factor
溶解的o2浓度影响PAO2.	可用O的数量2binding sites and the PAO2affect the SAO2.

概括– PAO₂vs SAO₂

PAO₂and SAO₂define cardiac efficiency and are considered as markers to assess the metabolic conditions of the lungs and heart in terms of Oxygen levels. PAO₂是由O施加的压力吗₂on the arterial wall. SAO₂血红蛋白结合位点的比例是are occupied with O_2.This is the main difference between PAO2 and SAO2. The normal PAO₂of a healthy person should lie above 17 kPa or 128 mmHg which will result in a 100% SAO₂而普通的₂is greater than 90%. Deviations of these levels act as markers and are important in analyzing the abnormalities in hemoglobins and Carbon monoxide poisoning.

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参考：

1.Collins，Julie-Ann等。“将氧局部压力，饱和度和含量相关：血红蛋白 - 氧解离曲线。”呼吸，欧洲呼吸学会，2015年9月，Available here. Accessed 21 Aug. 2017.

Image Courtesy:

1.”ratznium在英语Wikipedia上的氧降压蛋白解离曲线”，后来由Aaronsharpe上传到En.Wikipedia。- 从En.Wikipedia转移到Commons。（公共领域）通过Commons Wikimedia