Key Difference – PAO2 vs SAO2
The transport ofoxygen (O2)by blood in thearteriesis a critical process and is governed by many factors such asphof the blood,partial pressuresof the gases in blood, saturation levels of O2, concentration of available血红蛋白and cardiac efficiency. The balance of these factors will assure the efficient transport of O2根据特定组织的需求来进行外围组织。O的部分压力和O的饱和度2是两个非常重要的参数,这些参数决定了O的健康运输2in blood that is characterized by the Oxygen-Hemoglobin dissociation curve which depicts the saturation of hemoglobin with O2, the partial pressure and the concentration of O2in blood.The partial pressure of O2(PAO2) is the pressure exerted by O2在动脉壁上而O的饱和度2(SAO2) is the overall percentage of hemoglobin binding sites occupied by O2.This is the key difference between PAO2 and SAO2.
内容
1.Overview and Key Difference
2.What is PAO2
3.What is SAO2
4.Similarities Between PAO2and SAO2
5.Side by Side Comparison – PAO2vs SAO2以表格形式
6.概括
What is PAO2?
部分压由道尔顿的部分压力定律定义,其中指出系统的总压力等于混合物中存在的气体所施加的个别压力的总和。通过假设允许血液与一定数量的气体平衡,可以测量血液中溶解气体的部分压力。因此,Partial Pressure of O2(PAO2) also known as theO2tension in blood, is the pressure exerted by O2on the arterial wall. It is important to note that O2在血液中溶解在其他气体的混合物中carbon dioxide and carbon monoxide, but O2is the only gas that exerts a pressure on the arterial wall.
When the concentration of O2in the blood is higher, the PAO2also rises, allowing the blood to carry higher amounts of O2in comparison with other fluids such as water. Measuring and recording PAO2is important during disease states because there are certain physiological processes that depend on changes in O2在其微环境中,其特征是Pao的变化2.
What is SAO2?
O的饱和度2(SAO2) in blood defines the percentage of hemoglobin binding sites that are occupied by O2.Each hemoglobin molecule can occupy four O2molecules as it can allosterically modify its conformation to facilitate binding of O2to its binding site. During 100% saturation, all hemoglobin binding sites are occupied by O2,and any increase in partial pressure or the concentration of O2in blood would not cause an increase in saturation. This is depicted by the plateau area of the oxygen-hemoglobin dissociation curve. This saturation pattern is the reason for the characteristic sigmoid shaped curve of the O2– Hemoglobin curve.
What are the Similarities Between PAO2and SAO2?
- PAO2and SAO2depend on the concentration of O2present in the blood and lungs.
- 这两个参数都可以用作暗示血红蛋白失衡的指标。2,cardiac efficiency and respiratory efficiency.
- PAO2and SAO2are directly proportional until O2达到其最大饱和度。
What is the Difference Between PAO2and SAO2?
PAO2vs SAO2 |
|
PAO2是由O施加的压力吗2on the arterial wall. | SAO2血红蛋白结合位点的比例是are occupied by O2. |
表达单位 | |
PAO2is expressed in Pascal (pressure measuring units). | SAO2is expressed as a percentage. |
Depending Factor | |
溶解的o2浓度影响PAO2. | 可用O的数量2binding sites and the PAO2affect the SAO2. |
概括– PAO2vs SAO2
PAO2and SAO2define cardiac efficiency and are considered as markers to assess the metabolic conditions of the lungs and heart in terms of Oxygen levels. PAO2是由O施加的压力吗2on the arterial wall. SAO2血红蛋白结合位点的比例是are occupied with O2.This is the main difference between PAO2 and SAO2. The normal PAO2of a healthy person should lie above 17 kPa or 128 mmHg which will result in a 100% SAO2而普通的2is greater than 90%. Deviations of these levels act as markers and are important in analyzing the abnormalities in hemoglobins and Carbon monoxide poisoning.
Download PDF Version of PAO2 vs SAO2
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参考:
1.Collins,Julie-Ann等。“将氧局部压力,饱和度和含量相关:血红蛋白 - 氧解离曲线。”呼吸,欧洲呼吸学会,2015年9月,Available here. Accessed 21 Aug. 2017.
Image Courtesy:
1.”ratznium在英语Wikipedia上的氧降压蛋白解离曲线”,后来由Aaronsharpe上传到En.Wikipedia。- 从En.Wikipedia转移到Commons。(公共领域)通过Commons Wikimedia
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