Difference Between Basophil and Eosinophil

关键区别 - 嗜碱性粒细胞与嗜酸性粒细胞

Let us first briefly look at the composition of blood, to understand the Difference Between Basophil and Eosinophil clearly. Blood is mainly composed of white blood cells, red blood cells, platelets, and plasma. Plasma is the fluid part of the blood and represents more than half of blood’s volume.White blood cellsmake up about 1% of the entire blood volume, and red blood cells make up about 45%. The white blood cells or leukocytes are classified into cells with or without granules. Granular leukocytes include neutrophils, eosinophil and basophil and nongranular leukocytes include lymphocytes and monocytes. Thekey differencebetween basophil and eosinophil is that嗜碱性粒细胞可以通过释放肝素，组胺和5-羟色胺来刺激炎症反应while嗜酸性粒细胞s provide important defense against parasites by phagocytosis and producing antihistamines.

What is Basophil?

Basophils are granularleukocyteswith an S-shaped multi-lobednucleusand are similar to the size of eosinophils. These cells stimulate inflammation responses by releasing heparin, histamine, and serotonin. Biologists believe that basophils are produced and matured in thebone marrow. Certain morphological and functional features of basophils are equal to mast cells, which are common in组织。嗜碱粒细胞并不健康的血液humans, because once they release, they circulate for a few hours in the blood and migrate to the tissues where they last a few days. Basophils have relatively few granules, which are water soluble. Therefore, identifying basophils in blood is quite difficult. However, when basic stains are used to identify, thecytoplasm嗜碱性粒细胞染色的蓝色。

什么是嗜酸性粒细胞？

嗜酸性粒细胞s are bone marrow derived granular leukocytes with two-lobed nucleus. They provide an important defense against parasites by phagocytosis and produce antihistamines. When acid stains are used, the cytoplasm of the eosinophil stains in red. Usually, 1% to 5% of white blood cells are eosinophils. Very low number of eosinophils are found in the blood circulation of healthy persons because these cells are primarily tissue-dwelling cells.

What is the difference between Basophil and Eosinophil?

Characteristics ofBasophil and Eosinophil

Nucleus of cell

Basophil:Basophil has S-shaped multi-lobed nucleus.

嗜酸性粒细胞：嗜酸性粒细胞具有两杆核。

Staining color

Basophil:Cytoplasm of basophil stains blue in basic stains.

嗜酸性粒细胞：Cytoplasm of eosinophil stains red in acid stains.

Abundance

Basophil:0.5% or less of leukocytes are basophils.

嗜酸性粒细胞：1-5 % of leukocytes are eosinophils.

Function

Basophil:嗜碱性粒细胞可以通过释放肝素，组胺和5-羟色胺来刺激炎症反应.

嗜酸性粒细胞：嗜酸性粒细胞s provide important defense against parasites by phagocytosis and produce antihistamines.

Image Courtesy:

“Blausen 0352 Eosinophil” by BruceBlaus. When using this image in external sources it can be cited as:Blausen.com staff. “Blausen gallery 2014”. Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018762. – Own work.(CC BY 3.0 )viaWikimedia Commons

“Blausen 0077 Basophil” by BruceBlaus. When using this image in external sources it can be cited as:Blausen.com staff. “Blausen gallery 2014”. Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018762. – Own work.(CC BY 3.0)viaWikimedia Commons