Vascepa和鱼油有什么区别

TheVascepa和鱼油之间的关键区别is that Vascepa contains only eicosapentaenoic acid, whereas fish oil contains both eicosapentaenoic acid and docosahexaenoic acid.

Vascepa and fish oil are two commercially available dietary sources ofomega-3 fatty acids. Vascepa is the brand name of ethyl eicosapentaenoic acid. Fish oil is oil obtained from the tissues of oily fish.

内容

1.Overview and Key Difference
2.What is Vascepa
3.What is Fish Oil
4.Vascepa vs Fish Oil in Tabular Form
5.Summary – Vascepa vs Fish Oil

什么是Vascepa？

Vascepa is the brand name of ethyl eicosapentaenoic acid. It is a medication useful in treating血脂异常and hypertriglyceridemia. We can use this medication in combination with changes in diet in adults having hypertriglyceridemia. Moreover, it is often used with a statin. Usually, Vascepa is made from omega-3 fatty acid eicosapentaenoic acid. After the approval of the FDA in 2012, it became the second fish-oil-based medication after omega-3 acid ethyl esters (brand name is Lovaza).

There can be some common side effects of this medication: musculoskeletal pain, peripheral edema, atrial fibrillation, and arthralgia. Moreover, there can be some other side effects such as bleeding, constipation, gout, and rash. The approval from FDA for this medication has been given as a generic medication. The chemical formula of ethyl eicosapentaenoic acid is C22H34O2.

Vascepa is useful mainly as a dietary supplement. It is a fish-oil-based drug other than omega-3-acid ethyl esters and omega-3 carboxylic acids. These three dietary supplements have similar uses and mechanisms of action.

The active metabolite of Vascepa is eicosapentanoic acid. It appears to reduce the production oftriglyceridesin the liver and to enhance the clearance of triglycerides from the circulation of the very low-density lipoprotein particles. The potential mechanisms of action for this medication include increased breakdown of fatty acids, inhibition of diglyceride acyltransferase, and increased activity of lipoprotein lipase in the blood.

What is Fish Oil?

Fish oil is oil obtained from the tissues of oily fish. Fish oil usually contains omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid. These are the precursors of certain eicosanoids that can reduce the inflammation of the body and can improve the hypertriglyceridemia condition.

最近的发现证明，鱼油补充剂可以降低心血管疾病的风险。此外，它在许多其他疾病中也很有用，包括临床抑郁，焦虑，癌症和黄斑变性。

Although the source of fish oil is fish, they do not actually produce omega-3 fatty acids. They accumulate the acids by consuming either microalgae or prey fish consisting of omega-3 fatty acids.

eicosapentaenoic酸最常见的饮食来源是冷水油，包括鲑鱼，鲱鱼，鲭鱼，凤尾鱼和沙丁鱼。这些类型的鱼类中omega-3脂肪酸的含量比omega-6脂肪酸的含量高约7倍。

Vascepa和鱼油有什么区别?

Vascepa is the brand name of ethyl eicosapentaenoic acid. Fish oil is an oil obtained from the tissues of oily fish. The key difference between Vascepa and fish oil is that Vascepa contains only eicosapentaenoic acid, whereas fish oil contains both eicosapentaenoic acid and docosahexaenoic acid.

The below infographic presents the differences between Vascepa and fish oil in tabular form for side by side comparison.

Summary – Vascepa vs Fish Oil

Vascepa and fish oil are two commercially available dietary sources of omega-3 fatty acids. The key difference between Vascepa and fish oil is that Vascepa contains only eicosapentaenoic acid, whereas fish oil contains both eicosapentaenoic acid and docosahexaenoic acid.

Reference:

1.“”Vascepa: Uses, Dosage & Side Effects.”Drugs.com.

Image Courtesy:

1.“”乙酰烯基烯酸酯” Edgar181（谈话） - 通过Commons Wikimedia自己的作品（公共领域）
2. “Lachsölkapsel” By Marco Almbauer – Own work(CC BY-SA 4.0)via Commons Wikimedia