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RNA聚合酶I II和III之间的差异

2018年1月31日发表Samanthi博士

关键差异 - RNAPolymerase I vs II vs III

RNA polymerase is an essential enzyme found in all organisms and many viruses. It is the enzyme responsible for synthesizing RNA molecule from DNA template during the process known as转录。DNA序列中存储的遗传信息被转换为mRNA序列,该反应是由RNA聚合酶催化的。这是一个复杂的蛋白质分子由不同的亚基组成。Prokaryotespossess the single type of RNA polymerase (Prokaryotic RNA Polymerase).真核生物包含几种类型的RNA聚合酶(真核RNA聚合酶)。他们是RNA聚合酶I, II, III, IV和vmong them RNA polymerase I, II and III are the main types. Each type is responsible for the synthesis of a distinct subset of RNA.RNA聚合酶I催化DNA的转录rRNAof the large subunit of theribosome。RNA聚合酶I。I is the type of RNA polymerase that transcribes thecoding strandof the DNA, which produces the mRNA. RNA polymerase III transcribes the DNA that results in rRNA of the small subunit of ribosome andtRNA。这是关键区别between RNA polymerase I, II, and III.

CONTENTS

1。概述和关键差异
2。什么是RNA聚合酶I
3。什么是RNA聚合酶II
4。什么是RNA聚合酶III
5。Similarities Between RNA Polymerase I II and III
6.并排比较 - RNA聚合酶I VS II与III的表格形式
7.Summary

什么是RNA聚合酶i?

RNA聚合酶I是一种在较高的真核生物中发现的RNA聚合酶。它催化rRNA分子的转录。RNA pol I的分子大小为590 kDa。它由14个不同多肽(subunits).

RNA聚合酶I II和III之间的差异

Figure 01: RNA polymerase I

RNA聚合酶I不依赖于启动子区域中的Tata盒。它需要位于-200和-107之间的上游控制元素以及-45和+20区域中的核心元素。

什么是RNA聚合酶II?

RNA聚合酶II是一种真核RNA聚合酶。它催化了DNA的trancriptim,编码mRNA和大多数snRNA的前体的合成和microRNA。

Key Difference Between RNA Polymerase I vs II and III

Figure 02: RNA Polymerase II

RNA聚合酶II由12个蛋白质亚基组成,大小为500 kDa。到目前为止,它是研究最广泛的RNA聚合酶类型。

什么是RNA聚合酶III?

RNA聚合酶III是一种真核RNA聚合酶,负责核糖体5S rRNA,tRNA和其他小RNA的转录。这是催化所有细胞类型和大多数环境条件下所有管家基因转录的酶。RNA聚合酶的大小在500 - 700 kDa之间。它是最大的真核RNA聚合酶。

What are the Similarities Between RNA Polymerase I II and III?

  • RNA聚合酶I,II和III是三种类型的真核RNA聚合酶。
  • All enzymes are complex, multi-subunit proteins.
  • 所有酶均负责转录。
  • All enzymes require a DNA template to produce RNA.
  • 所有酶都需要辅助蛋白因子来结合和开始转录。

What is the Difference Between RNA Polymerase I II and III?

RNA聚合酶I与RNA聚合酶II与RNA聚合酶III

RNA聚合酶I。 RNA聚合酶I是合成大型RRNA亚基的RNA聚合酶的类型。
RNA聚合酶I。I RNA聚合酶I。I is the type of RNA polymerase that synthesizes mRNA and snRNA and microRNA.
RNA聚合酶I。II RNA聚合酶I。II is the type of RNA polymerase that catalyzes the synthesis of tRNA and the small subunit of rRNA.
Sub Units
RNA聚合酶I。 RNA聚合酶I有14个亚基。
RNA聚合酶I。I RNA聚合酶I。I has 12 subunits.
RNA聚合酶I。II RNA聚合酶III具有17个亚基。
尺寸
RNA聚合酶I。 RNA聚合酶的大小I AM 590 kDa。
RNA聚合酶I。I 尺寸of the RNA polymerase II is 500 kDa.
RNA聚合酶I。II RNA聚合酶I。II is 700 kDa.

摘要 - RNAPolymerase I vs II vs III

RNA polymerase is the enzyme that catalyzes the transcription process. It synthesizes RNA molecules from a DNA template. Hence, it is also known as DNA dependent RNA polymerase. There are three main types of RNA polymerases in eukaryotes namely RNA polymerase I, II and III. RNA polymerase I is responsible for the synthesis of the large subunit of ribosomal RNA. RNA polymerase II catalyzes the synthesis of precursors of the mRNA molecules and other snRNA and microRNA. RNA polymerase III is the enzyme that transcribes the DNA that results in the small subunit of rRNA and tRNA. This is the difference between RNA polymerase I, II and III.

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参考:

1.“ RNA聚合酶III。”RNA聚合酶III - 概述|ScienceDirect主题。在这里可用
2. Paule,Marvin R.和Robert J. White。“ RNA聚合酶I和III的转录。”核酸研究,牛津大学出版社,2000年3月15日。在这里可用
3.“ RNA聚合酶。”。RNA聚合酶 - 概述|ScienceDirect主题。在这里可用

图片提供:

1。’GE23077-binds-to-the-RNA-polymerase-i-and-i+1-sites-and-prevents-the-binding-of-initiating-elife02450fs004’By Zhang Y, Degen D, Ho M, Sineva E, Ebright K, Ebright Y, Mekler V, Vahedian-Movahed H, Feng Y, Yin R, Tuske S, Irschik H, Jansen R, Maffioli S, Donadio S, Arnold E, Ebright R (2014).(CC由3.0)通过下议院维基梅迪亚
2.’RNA聚合酶II.FCGI’BY MEYER PA,YE P,ZHANG M,SUH MH,FU J -NIH的NCBI,(公共领域)通过下议院维基梅迪亚

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提交以下:分子生物学Tagged With:比较RNA聚合酶I II和III,,,,RNA Polymerase I,,,,RNA聚合酶I定义,,,,RNA聚合酶I II和III差异,,,,RNA聚合酶I II和III相似性,,,,RNA Polymerase I II vs III,,,,RNA聚合酶i sizer,,,,RNA聚合酶I子单元,,,,RNA聚合酶II,,,,RNA聚合酶IIDefinition,,,,RNA聚合酶II尺寸,,,,RNA聚合酶IISub units,,,,RNA聚合酶III,,,,RNA聚合酶IIIDefinition,,,,RNA聚合酶III大小,,,,RNA聚合酶III子单元

关于作者:Samanthi博士

Samanthi博士Udayangani holds a B.Sc. Degree in Plant Science, M.Sc. in Molecular and Applied Microbiology, and PhD in Applied Microbiology. Her research interests include Bio-fertilizers, Plant-Microbe Interactions, Molecular Microbiology, Soil Fungi, and Fungal Ecology.

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