蛋白酶和蛋白酶之间的差异

关键差异 - 蛋白酶与蛋白酶

Proteinsare composed of氨基酸monomersmade of Carbon, Hydrogen, Oxygen, and Nitrogen. They are大分子and are structurally arranged into different levels. Proteins play an important role in both structural and functional properties of the body. Protein is an essential nutrient and can be obtained from both animal and plant food sources. Protein digestion starts in the stomach and ends in thesmall intestinewhere it is absorbed and transported to target organs. Protein degradation is also a vital process in many industries including leather industry, wool industry, food industry and in genetic engineering techniques. Protein degradation or proteolysis is an enzyme-catalyzed reaction taking place with the involvement of a specialized enzyme type known as hydrolases. Protease and Proteinases are two such hydrolases involved in protein degradation.Proteases are involved in the cleavage of thepeptide bondin proteins, causing the degradation of the proteins. Proteinases are a type of protease which is capable of cleaving the internalpeptide bonds.这是蛋白酶和蛋白酶之间的关键区别。

内容

1.Overview and Key Difference
2.What is Protease
3.What is Proteinase
4.蛋白酶和蛋白酶之间的相似性
5.并排比较 - 蛋白酶与表格形式的蛋白酶
6。概括

什么是蛋白酶？

Proteases belong to the class of Enzyme commission number 3 (EC3). It is a type of hydrolase and participates in anucleophilic reaction与底物。蛋白酶激活Anucleophilewhich will attack the carbon of the peptide bond. This nucleophilic attack will result in the formation of a high-energy intermediate compound which will quickly return to stability by degradation. This will result in the cleavage at the peptide bond, resulting in two fragments of peptides. There are four main types of proteases: aspartic proteases, cysteine proteases, aspartyl proteases and metalloproteases. The method of nucleophilic attack differs in each enzyme class.

Proteases are used under natural conditions in protein digestion and under industrial conditions to produce commercial products. Proteases are further divided as exopeptidases and endopeptidases.

Industrially, proteases are mainly used in the leather and food industry. At present, proteases are used in the commercial production of many enzymes and other protein production industries. They are also used in the field of biotechnology to facilitate genetic engineering methods.

什么是蛋白酶？

Proteinase is a type of protease. The action of Proteinase is similar to a protease, and it acts as a hydrolase. Proteinase is an endo-peptidase and participates in cleaving the internal peptide linkages of long peptide chains. These can also be intra-peptide linkages of complex proteins.

蛋白酶在正常的生理功能和工业目的中也很重要。

What are the Similarities Between Protease and Proteinase?

• Both are hydrolases.
• 两者都充当蛋白水解酶。
• 重组DNA技术目前用于生产这两种酶。
• Both enzymes cleave the peptide bond of proteins and degrading proteins.
• Both enzymes are used in industries – leather industry, wool industry, food industry and recombinant DNA technology and proteomics.
• 在生理学中，蛋白酶和蛋白酶用于消化

What is the Difference Between Protease and Proteinase?

Protease vs Proteinase
蛋白酶是在蛋白质中切割肽键的酶。	蛋白酶是一种能够裂解内部肽链接的蛋白酶。
行动
蛋白酶可以endo- peptidases or exo-peptidases.	Proteinases are endo-peptidases.

摘要 - 蛋白酶与蛋白酶

蛋白酶和蛋白酶是蛋白水解水解酶，用于各种目的。蛋白酶是在蛋白质中切割肽键的酶。蛋白酶是一种裂解内部肽链接的蛋白酶。这是蛋白酶和蛋白酶之间的基本差异。

下载PDF版本的蛋白酶与蛋白酶

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参考：

1. Mótyán, JánosAndrás, et al. “Research Applications of Proteolytic Enzymes in Molecular Biology.” Biomolecules, MDPI, Dec. 2013,Available here. Accessed 15 Sept. 2017.
2. “Structural Biochemistry/Enzyme Catalytic Mechanism/Proteases.” Structural Biochemistry/Enzyme Catalytic Mechanism/Proteases – Wikibooks,Available here. Accessed 15 Sept. 2017.

Image Courtesy:

1.托马斯·沙菲（Thomas Shafee） - 托马斯（Thomas），沙菲（Shafee）（2014年）的“ TEV蛋白酶摘要”。“病毒蛋白酶的发展性：催化，鲁棒性和特异性的实验演变”。博士论文。剑桥大学(CC BY 4.0)viaCommons Wikimedia
2. “PDB 1PEK EBI” By Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute – displayed这里（公共领域）通过Commons Wikimedia