之间的区别Neutrophils and Macrophages

这关键区别between neutrophils and macrophages is that中性粒细胞不是抗原呈递细胞，而巨噬细胞是抗原呈递细胞。

中性粒细胞和巨噬细胞是白细胞属于innate immune system，他们是反对的主要初始捍卫者病原体。这se specialized cells can squeeze through the small holes of blood vessels during a process called diapedesis, which ultimately enables them to travel to the areas of infection easily. Normally, an inflammatory reaction takes place during tissue damage. This is due to the chemical substances released by bacteria into the surrounding tissue and blood. These chemicals eventually trigger the attraction of neutrophils and macrophages towards these chemical substances through chemotaxis. Hence, this is the first significant reaction of defense action against pathogens. Moreover, both types of cells can phagocytize pathogens in the infected area.

CONTENTS

1。概述和关键差异
2。What are Neutrophils
3。什么是巨噬细胞
4.Similarities Between Neutrophils and Macrophages
5.Side by Side Comparison – Neutrophils vs Macrophages in Tabular Form
6.Summary

什么是中性粒细胞？

Neutrophils are the most abundant type of white blood cells in the blood. Neutrophils are also the most abundant type of粒细胞。这y act as the first line of defense when there is an inflammatory reaction or an infection.

此外，它们是最终分化的细胞，其中包含大量蛋白水解酶和活性氧，当释放到细胞外基质中时会导致局部组织损害。在骨髓中发展中性粒细胞大约需要14天。之后，他们开始在血液中循环6至14小时。近50％的循环中性粒细胞粘附在血管内皮上。这些中性粒细胞可以再生存48小时，这与未附着在血管内皮上的其他中性粒细胞不同。

什么是巨噬细胞?

巨噬细胞是识别，吞噬和破坏外国入侵者的变性大型专门细胞。他们是大徒步旅行者的受欢迎。此外，它们通过吞噬微观碎片来清洁我们的身体。他们是先天系统的最古老的调解人。此外，它们起源于骨髓中的单核细胞。单核细胞被释放并迁移到各种组织中时分化为巨噬细胞。由于它们在组织中发展，因此我们称它们为组织巨噬细胞。组织巨噬细胞可以生存数月至数年，直到需要它们在执行防御功能后被破坏。组织巨噬细胞非常重要，因为它们是针对细胞内病原体的防御系统的主要效应子。

巨噬细胞使用称为吞噬作用的过程来摧毁并摆脱体内不需要的事物。吞噬作用始于由于吞噬颗粒而形成一个称为吞噬体的口袋样结构。然后，使用溶菌酶释放的酶，它们消化了吞噬体中的颗粒。

What are the Similarities Between Neutrophils and Macrophages?

• Both neutrophils and macrophages are white blood cells.
• Also, both arephagocytes。
• 而且，他们俩都反对感染。
• Besides, they originate at the bone marrow.

What is the Difference Between Neutrophils and Macrophages?

中性粒细胞和巨噬细胞之间的关键区别在于表现抗原的能力。与中性粒细胞不同，巨噬细胞可以在吞噬细菌细胞后MHC（主要的组织相容性复合物）II类分子的情况下向T淋巴细胞呈现抗原片段。此外，巨噬细胞的寿命比中性粒细胞更长。因此，这是中性粒细胞和巨噬细胞之间的另一个区别。

同样，中性粒细胞和巨噬细胞之间的另一个差异是它们的大小。巨噬细胞大于中性粒细胞。由于巨噬细胞大于中性粒细胞，因此它们可以比中性粒细胞吞噬更多的侵袭者病原体。感染后，嗜中性粒细胞尽早占据感染部位，而巨噬细胞在后期（感染后1至2天）主导感染部位。因此，这也是中性粒细胞和巨噬细胞之间的差异。

Furthermore, another difference between neutrophils and macrophages is that neutrophils have a multi-lobed nucleus while the nucleus of macrophage is big and round shaped. The below infographic on the difference between neutrophils and macrophages provides more details on the comparative differences.

Summary – Neutrophils vs Macrophages

血液包含不同类型的血细胞。White blood cells are a major type among them. There are different types of white blood cells (leukocytes) such as monocytes, lymphocytes, neutrophils, eosinophils, basophils, and macrophages. Neutrophils and macrophages are two common types of white blood cells that work against an infection. While neutrophils are the most abundant white blood cells, macrophages are the large specialized cells that are known as big eaters. Neutrophils do not have the capability to present antigens while macrophages are professional antigen presenting cells. Furthermore, when there is an infection, neutrophils come first while macrophages come later. This summarizes the difference between neutrophils and macrophages.

参考：

1.“中性粒细胞。”神经图像，学术出版社，在这里可用。
2.“巨噬细胞：定义，功能和类型”，study.com，在这里可用。

图片提供：

1。“Blausen 0676 Neutrophil (crop)” By Blausen.com staff (2014). “Medical gallery of Blausen Medical 2014”. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436（CC BY-SA 4.0）通过下议院维基梅迪亚
2. A. Rad，MikaelHäggström，Spacebirdy，Rexxs，Domdomegg - 文件：造血（人）图（CC BY-SA 4.0）通过下议院维基梅迪亚