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Difference Between L-serine and Phosphatidylserine

March 23, 2020Posted byDr.Samanthi

Thekey differenceL-serine和磷脂酰丝氨酸之间L-serine is anonessential amino acidwhich is essential for the synthesis of phosphatidylserine while phosphatidylserine is aphospholipidand a component of the cell membrane.

L丝氨酸和磷脂酰丝氨酸是我们体内发现的两种重要化学物质。L-丝氨酸是一种非必需的氨基酸,是在我们体内产生的,并且是天然存在的饮食氨基酸。另一方面,磷脂酰丝氨酸是一种磷脂,它是生物膜中的主要成分。L丝氨酸对于合成磷脂酰丝氨酸至关重要。

内容

1.Overview and Key Difference
2.什么是l-serine
3.What is Phosphatidylserine
4.Similarities Between L-serine and Phosphatidylserine
5.Side by Side Comparison – L-serine vs Phosphatidylserine in Tabular Form
6。概括

什么是l-serine?

L-serine is a nonessential, naturally occurring dietary amino acid. The chemical formula of L-serine is C3H7不3and its molecular mass is 105.09 g/mol. L-serine is essential for the biosynthesis of proteins, purines, pyrimidines, other amino acids such asglycine以及L-半胱氨酸和细胞膜脂质,例如磷脂和鞘脂。此外,L丝氨酸对于细胞增殖和细胞内代谢很重要。上床前的L塞林摄入量可以提高睡眠质量。此外,L serine转化为D丝氨酸,这是一种辅助神经递质,L链也是中枢神经系统中的神经营养因子。

Difference Between L-serine and Phosphatidylserine

Figure 01: L-serine

Our body synthesizes L-serine endogenously from two main ways. One way is from glycine in the reverse reactions catalyzed by serine hydroxymethyltransferase. The second way is from the glycolytic intermediate 3-phosphoglycerate in three enzymatic steps. In addition, L-serine is abundant in soy products, some edible seaweeds, sweet potatoes, eggs and meat.

What is Phosphatidylserine?

磷脂酰丝氨酸是一种内源性磷脂和饮食营养素。实际上,它是一种甘油磷脂(基于甘油的磷脂),它是生物膜的主要组成部分。从结构上讲,磷脂酰丝氨酸具有两个脂肪酸链,该脂肪酸连接到两个碳甘油的碳和丝氨酸附着在甘油的第三碳上。因此,L-丝氨酸是合成磷脂酰丝氨酸的必需氨基酸。磷脂酰丝氨酸的化学式为c13H24不10p的分子质量为385.304 g/mol。

Key Difference - L-serine vs Phosphatidylserine

图02:磷脂酰丝氨酸

从功能上讲,磷脂酰丝氨酸在细胞信号传导中起主要作用。磷脂酰丝氨酸覆盖并保护脑细胞,并有助于在神经之间传输信息。此外,它有助于保持思想和记忆力,改善情绪并促进健康的睡眠。最重要的是,磷脂酰丝氨酸在血液凝结中起关键作用,作为促凝结剂表面。

Our body produces all phosphatidylserine it needs. Phosphatidylserine coming from plants differs structurally from phosphatidylserine coming from animals due to the difference in the fatty acid chain compositions. Soy and cabbage are two key plant sources of phosphatidylserine. Meat and fish are two animal sources of phosphatidylserine.

What are the Similarities Between L-serine and Phosphatidylserine?

  • L-serine is an amino acid essential for the synthesis of phosphatidylserine.
  • Both L-serine and phosphatidylserine are naturally occurring in soy products, meat, etc.
  • 此外,我们的身体同时产生L丝氨酸和磷脂酰丝氨酸。

What is the Difference Between L-serine and Phosphatidylserine?

L-丝氨酸是一种非必要的,天然存在的饮食氨基酸,对于蛋白质,嘌呤,嘧啶,其他氨基酸和脂质的生物合成至关重要。另一方面,磷脂酰丝氨酸是一种内源性磷脂和饮食营养素,它是生物膜的主要组成部分。因此,这是L丝氨酸和磷脂酰丝氨酸之间的关键区别。此外,L丝氨酸的化学公式为c3H7不3磷脂酰丝氨酸的化学式为c13H24不10P

Moreover, the molecular mass of L-serine is 105.09 g/mol while the molecular mass of phosphatidylserine is 385.304 g/mol. L-serine is essential for the biosynthesis of proteins, nucleotides, neurotransmitters, and lipids. It is also important for cell proliferation and intracellular metabolism and improves sleep quality. In contrast, phosphatidylserine plays a major role in cell signalling and it covers and protects brain cells and helps in transmitting messages between nerves. Besides, it plays a key role in blood coagulation working as a pro-coagulant surface. Therefore, this is the functional difference between L-serine and phosphatidylserine.

Difference Between L-serine and Phosphatidylserine in Tabular Form

概括– L-serine vs Phosphatidylserine

L-serine is a nonessential amino acid that is essential for the synthesis of proteins, nucleotides, neurotransmitters, and lipids. Moreover, it is important for brain development and metabolism. On the other hand, phosphatidylserine is a phospholipid which is an essential component in the cell. Most importantly, L-serine is essential for the synthesis of phosphatidylserine. Both compounds are produced in our body and they are dietary nutrients. This is the summary of the difference between L-serine and phosphatidylserine.

Reference:

1. “Phosphatidylserine.” Winchester Hospital,Available here.
2.“ l-serine。”美国化学学会,Available here.

Image Courtesy:

1. “L-serine-skeletal” By Benjah-bmm27 assumed – No machine-readable source provided. Own work assumed (based on copyright claims). (Public Domain) viaCommons Wikimedia
2. “Phosphatidylserine” By Zirgouflex – Own work (Public Domain) viaCommons Wikimedia

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Filed Under:Biochemistry

关于the Author:Dr.Samanthi

Samanthi Udayangani博士拥有B.Sc.植物科学学位,硕士在分子和应用微生物学和应用微生物学中的博士学位。她的研究兴趣包括生物肥料,植物 - 微生物相互作用,分子微生物学,土壤真菌和真菌生态学。

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