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Difference Between Genetic Map and Linkage Map

September 3, 2019Posted byDr.Samanthi

Thekey difference遗传图和连锁图之间是用于映射过程的基因的类型。Genetic map consists of all genes present on a particular染色体while linkage map consists oflinked genespresent on a particular chromosome.

遗传图和链接图是两种类型的染色体图,这些类型说明了染色体上发现的基因。遗传图显示了所有基因,而连锁图仅显示链接基因。两者在诊断遗传疾病和疾病方面都非常有用。此外,染色体畸变can also be detected using genetic and linkage maps. Linkage maps further provide an idea of the evolution of particular genes.

内容

1.Overview and Key Difference
2.What is Genetic Map
3.What is Linkage Map
4.Similarities Between Genetic Map and Linkage Map
5.并排比较,遗传图谱和链接ap in Tabular Form
6.概括

What is a Genetic Map?

Genetic map is the complete map of genes in a chromosome. This is also known as chromosome mapping. This will provide information on the specific genes located in the chromosome. Moreover, the genetic mapping process utilizes physical mapping method to locate genes on the chromosomes.

Key Difference - Genetic Map vs Linkage Map

图01:遗传图

Genetic mapping can also find chromosomal aberrations. Therefore, the genetic map acts as a diagnostic tool to detect conditions such as Downs syndrome and Turners syndrome. Karyotyping is one technique that can be used to generate a genetic map. Furthermore, staining is an important technique to generate a genetic map. Different types of stains such as ethidium bromide, acridine orange and Giemsa are utilized in staining.

What is a Linkage Map?

The linkage gene map utilizes the concept of genetic linkage. Therefore, a linkage map shows the linked gens present on a chromosome. This is often misinterpreted as a genetic map as well. Mapping of the linked genes determining the physical characteristics is important in genetic diagnostics. This also provides an idea about the inheritance of genes located very close to each other in a chromosome.

Difference Between Genetic Map and Linkage Map

Figure 02: Linkage Map

Linkage mapping also makes the researcher understand how genes exist precisely in a chromosome. It is also important in diagnosing diseases.

What are the Similarities Between Genetic Map and Linkage Map?

  • 遗传图和连锁图在诊断染色体畸变和遗传疾病的诊断中很重要。
  • 两者都使用染色技术在显微镜下可视化基因。
  • Moreover, karyotyping is the method we use in both mapping techniques.

What is the Difference Between Genetic Map and Linkage Map?

遗传图显示了染色体上存在的完整基因集。相反,连锁图仅显示染色体上存在的链接基因。因此,这是遗传图和链接图之间的关键区别。遗传图主要对于诊断疾病和检测染色体畸变至关重要,而连锁图主要可用于理解链接基因和相关遗传疾病的遗传和进化。这是遗传图和链接图之间的差异。Difference Between Genetic Map and Linkage Map - Tabular Form

概括– Genetic Map vs Linkage Map

Genetic mapping and linkage mapping are two mapping techniques used in genetic diagnosis. DNA is the source for both types of mapping. The genetic map illustrates all the genes in a particular chromosome while the linkage map shows the linked genes in a particular chromosome. This is the key difference between genetic map and linkage map. Karyotyping is the technique we use for both mapping techniques. It plays an important role in determining the evolution and genetic trends.

Reference:

1. “Genetic Linkage & Mapping.” Khan Academy, Khan Academy,Available here.
2.“基因图”。基因地图 - 概述|ScienceDirect主题,Available here.

Image Courtesy:

1. “NHGRI Fact Sheet- Genetic Mapping (27058469495)” By National Human Genome Research Institute (NHGRI) from Bethesda, MD, USA – NHGRI Fact Sheet: Genetic Mapping(CC由2.0)viaCommons Wikimedia
2. Twaanders17的“果蝇基因链接图” - 自己的作品(CC BY-SA 4.0)viaCommons Wikimedia

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Filed Under:Genetics

About the Author:Dr.Samanthi

Dr.Samanthi Udayangani holds a B.Sc. Degree in Plant Science, M.Sc. in Molecular and Applied Microbiology, and PhD in Applied Microbiology. Her research interests include Bio-fertilizers, Plant-Microbe Interactions, Molecular Microbiology, Soil Fungi, and Fungal Ecology.

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