这关键区别men1和men2是男人1(多个内分泌肿瘤1)是遗传的遗传性疾病导致肿瘤在pituitary gland,,,,甲状旁腺,,,,and the胰腺,而男性2(多个内分泌肿瘤2)是一种遗传疾病,会导致肿瘤中的肿瘤thyroid gland,,,,甲状旁腺,,,,or adrenal gland.
这endocrine system is made up of glands and cells that produce hormones and release them into the blood. Multiple endocrine neoplasia (MEN) is an inherited genetic disorder that affects the endocrine system. There are several types of multiple endocrine neoplasia syndromes that cause different types of tumors.
CONTENTS
1。概述和关键差异
2。什么是men1(多个内分泌肿瘤1)
3。什么是men2(多个内分泌肿瘤2)
4。相似之处 - men1和men2
5。men1 vs men2表格形式
6.摘要 - Men1 vs Men2
什么是Men1(多个内分泌肿瘤1)?
多内分泌肿瘤1(男子1)是一种遗传性遗传疾病,可导致垂体,甲状旁腺和胰腺中的肿瘤。有时被称为Wermer综合征,,,,正如保罗·韦默(Paul Wermer)在1954年首次描述的那样。Men1通常是由突变引起的Men1基因。该基因提供了产生称为梅宁的蛋白质的说明。Menin蛋白在防止细胞生长和分裂过快方面起着至关重要的作用。该疾病显示常染色体显性遗传。
Generally, tumors in the above glands are benign. However, tumor growth in the pituitary gland, parathyroid gland, and pancreas can produce and release excessive hormones that lead to the disease. Excessive hormones can cause a wide variety of signs and symptoms. These signs and symptoms include tiredness, bone, pain, broken bones, kidney stones, and ulcers in the stomach. The diagnosis of this medical condition is normally made through blood tests, imaging testing (MRI, CT scan, PET scan, nuclear medicine scan, endoscopic ultrasound), and genetic testing. The treatments for MENI tumors in the pituitary gland, parathyroid gland, and pancreas include minimally invasive surgeries, chemotherapy, and radiation.
什么是men2(多个内分泌肿瘤2)?
Multipleendocrine neoplasia 2(MEN 2) is an inherited genetic disorder that causes tumours in the thyroid gland, parathyroid gland, or adrenal gland. This medical condition is due to a mutation in a gene called RET. RET is a proto-oncogene located on chromosome 10. When mutated, it becomes an oncogene and causes uncontrolled cell growth and tumor formation. MEN2 can be due to inherited mutations as well as sporadic mutations. It is divided into three types: MEN2A, familial modularly thyroid cancer, MEN2B.
这种疾病的症状和症状包括脖子前的肿块,说话困难,吞咽困难,呼吸困难,大淋巴结,喉咙和颈部疼痛,抑郁,焦虑,焦虑,头痛,困惑,恶心,恶心,缺乏食欲,腹痛,便秘,骨骼和关节疼痛,骨质疏松症,高血压,体重减轻,震颤,Alacrima,粘膜神经瘤,眼睑纵容和脊柱侧弯。诊断通常是通过家族史,体格检查,X射线检查和基因检测。The treatment options include removal of the gland through surgery (prophylactic thyroidectomy, removal of parathyroid gland, removal of adrenal gland), laparoscopic laparotomy, calcimimetics (control serum level of parathyroid hormone), alpha-adrenergic blockers, and beta-adrenergic blockers for hypertension
What are the Similarities Between MEN1 and MEN2?
- Men1和Men2是两种多种内分泌肿瘤。
- 两种类型都会在内分泌腺中引起肿瘤。
- Both types can occur as inherited conditions or sporadic conditions.
- If inherited, both types show autosomal dominant inheritance patterns.
- 在这两种情况下,肿瘤都可能是良性或癌性的。
- 这se conditions are treatable through surgeries.
Men1和Men2有什么区别?
男子1是一种遗传性遗传疾病,可导致垂体,甲状旁腺和胰腺中的肿瘤,而男性2是一种遗传性遗传疾病,可导致甲状腺腺,甲状旁腺或肾上腺的肿瘤。因此,这是Men1和Men2之间的主要区别。此外,Men1是由突变引起的Men1基因,而Men2是由突变引起的ret基因。
下面的图表展示了不同选择ween MEN1 and MEN2 in tabular form for side by side comparison.
摘要 - Men1 vs Men2
多内分泌肿瘤是一种遗传遗传病,涵盖了具有内分泌腺肿瘤的几种不同综合征。有些肿瘤是良性的,而另一些则是恶性的。Men1和Men2是两种多种内分泌肿瘤。男子1是一种遗传性遗传疾病,可导致垂体,甲状旁腺和胰腺中的肿瘤,而男性2是一种遗传性遗传疾病,可导致甲状腺,甲状旁腺或肾上腺的肿瘤。因此,这是Men1和Men2之间的主要区别。
参考:
1。“多内分泌肿瘤1型。”美国卫生与公共服务部国家糖尿病与消化研究所和肾脏疾病。
2.“”多内分泌肿瘤2型。”NORD(国家罕见疾病组织)。
图片提供:
1。“多内分泌肿瘤” By Mikael Häggström – Own work (CC0) via Commons Wikimedia
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