Difference Between Physiological and Pathological Jaundice

Key Difference –Physiologicalvs病理黄疸

人体粘膜层的淡黄色变色定义为黄疸。在健康的新生儿中，黄疸可能由于增加而出现hemolysisand the immaturity of theliver快速代谢bilirubinproduced during the process. This is known as physiological jaundice. Pathological jaundice can occur in any person and is a result of an ongoing pathological process that interrupts the normal bilirubin metabolism. As their names imply,in physiological jaundice there is no underlying pathological abnormality, unlike its counterpart that is always secondary to a pathological process that affects the normal bilirubin metabolism.This is thekey differencebetween the two conditions.

内容

1.Overview and Key Difference
2.What is Physiological Jaundice
3.什么是病理性黄疸
4.Similarities Between Physiological and Pathological Jaundice
5.Side by Side Comparison – Physiological vs Pathological Jaundice in Tabular Form
6。概括

What is Physiological Jaundice?

人体粘膜层的淡黄色变色定义为黄疸。This discoloration is due to the accumulation of bilirubin. During the hemolysis ofred blood cells,血红蛋白被分解为Haem和globin成分。通过血氧酶的作用将血红素转化为双脂蛋白，然后将其转化为unconjugated bilirubin。Due to the low water solubility of unconjugated bilirubin, it is transported into the liver via blood by binding to白蛋白。进入肝脏后，未结合的胆红素通过将水溶性分子附着在其上转化为共轭胆红素。之后，胆红素被释放到肠道中，正常的菌群作用在其上产生固定蛋白原，后来变成稳定蛋白。某些部分通过肾脏被排出为尿尿蛋白。

在健康的新生儿中，黄疸可能会出现，因为溶血的增加和肝脏在过程中迅速代谢胆红素的不成熟。生理黄疸通常在出生后2-3天出现，并逐渐达到高峰。无需进一步调查。有时，进行光疗以加速胆红素的崩溃

什么是病理性的黄疸？

病理性黄疸可能发生在任何人中，这是持续的病理过程中断正常胆红素代谢的结果。

Causes

• Hemolytic anemias and other red cell diseases
• Hemoglobinopathies
• 肝脏系统的阻塞
• Damages to the hepatic parenchyma as in肝硬化
• Infections such ashepatitis B
• Adverse effects of drugs

Investigations

Biochemical studies to measure the levels of total bilirubin, indirect and direct bilirubin are required. Depending on the suspected underlying cause, clinicians may go for other appropriate investigations.

治疗

根据底层路径管理不同ology that gives rise to jaundice. Once the cause has been aptly treated and eliminated jaundice will disappear spontaneously.

What is the Similarity Between Physiological and Pathological Jaundice?

• There is an increase in the level of bilirubin in both conditions.

生理和病理黄疸有什么区别？

生理黄疸vs病理黄疸
在健康的新生儿中，黄疸可能会出现，因为溶血的增加和肝脏在过程中迅速代谢胆红素的不成熟。这被称为生理黄疸。	病理性黄疸可能发生在任何人中，这是持续的病理过程中断正常胆红素代谢的结果。
病理
没有潜在的病理。	有一种潜在的病理。
受害者
Physiological jaundice is seen in neonates.	Pathological jaundice can occur in both adults and children.
治疗
无需治疗。	应根据黄疸的根本原因对患者进行治疗。

概括–Physiologicalvs病理黄疸

人体粘膜层的淡黄色变色定义为黄疸。在健康的新生儿中，黄疸可能会出现，因为溶血的增加和肝脏在过程中迅速代谢胆红素的不成熟。这被称为生理黄疸。病理性黄疸可能发生在任何人中，这是持续的病理过程中断正常胆红素代谢的结果。病理性的黄疸始终是由于病理过程，但生理黄疸并不是病理过程的次要。这是两个条件之间的主要差异。

Download the PDF Version of Physiological vs Pathological Jaundice

You can download the PDF version of this article and use it for offline purposes as per citation note. Please download the PDF version here:Difference Between Physiological and Pathological Jaundice

Reference:

1. Kumar，Parveen J.和Michael L. Clark。Kumar＆Clark临床医学。爱丁堡：W.B。桑德斯，2009年。印刷。

Image Courtesy:

1. jim Champion的Poorly Baby’(CC BY-SA 2.0)viaFlickr
2.’Jaundice eye new’By Jaundice_eye.jpg: * Photo Credit:Content Providers(s): CDC/Dr. Thomas F. Sellers/Emory Universityderivative work(Public Domain) viaCommons Wikimedia