Difference Between Globin and Globulin

Key Difference – Globin vs Globulin

Globin和globulins are majorproteinsof an organism. They are specialized for important functions in the blood stream. Globin proteins are specialized for oxygen binding and transporting oxygen from respiratory organs to other tissues. They are bound to heme groups. Globulins are a major type of blood proteins found inserum。They are responsible for several functions of the blood. The key difference between globin and globulin is thatglobins are heme-containing globular proteinswhileglobulins are simple globular proteins.

内容
1.Overview and Key Difference
2.What is Globin
3.什么是球蛋白
4.Side by Side Comparison – Globin vs Globulin
5.概括

What is Globin?

Globinis a superfamily of proteins found in the blood. They are popular as heme-containing globular proteins. There are two popular members of globin family namely血红蛋白和肌红蛋白。The major function of the globin protein is the transportation of oxygen from respiratory organs to other organs via红细胞。Globinproteins are composed of severalpolypeptides。They contain multi-subunit globular proteins.

In vertibrates, eight different globin proteins can be found. They are cytoglobin, androglobin, globin E, globin X, globin Y, myoglobin, haemoglobin, and neuroglobin. In bacteria,algae and cyanobacteria，球蛋白蛋白存在于不同类型中。

球蛋白是什么?

Globulin is a simple globular protein found in the血浆。它是一种主要的血液蛋白，占血液蛋白的一半。球蛋白蛋白可溶于盐，不溶于水。球蛋白蛋白参与血液中的多个功能，例如运输代谢物和metals and functioning asimmunoglobulins。Globulin concentration in human blood is about 2.6 – 4.6 g/dL. Globulins are in various sizes ranging from 93 kDa (lightest alpha globulin) to 1193 kDa (heaviest gamma globulin). Most of the globulin proteins are synthesized in the liver and immunoglobulins are produced by plasma cells.

Some globulins are immunologically active; they are referred as immunoglobulins or popular antibodies. Other globulin proteins act as carrier proteins, enzymes and complements in the blood. There are four major groups of globulin proteins. They are Alpha 1 globulins, Alpha 2 globulins, Beta globulins and Gamma globulins. Immunoglobulins belong to Gamma globulins and are a critical part of the immune system which protects the body from the pathogens.

What is the difference between Globin and Globulin?

Globin vs Globulin
Globinis a larger protein family.	Globulin is a protein found in the blood plasma.
Main Function
球蛋白蛋白主要参与生物体中的氧运输。	球蛋白蛋白在血液中涉及多个功能，包括免疫反应，酶促作用，金属的运输等。
Members
Two prominent members of globin protein are hemoglobin and myoglobin.	Immunoglobulins are one of the major types of globulins in the blood plasma.
Structure
球蛋白蛋白的几种多肽折叠在一起。	Globulin protein is a simple protein.

概括– Globin vs Globulin

球蛋白蛋白与血液中的氧运输有关。它们是含血红素的蛋白质的流行。球蛋白是血浆中发现的一组血液蛋白。它们充当血液中的酶，载体蛋白，补体和抗体。因此，球蛋白和球蛋白之间的主要区别在于它们的功能。

参考
1. Miller, L. L., F. S. Robscheit-Robbins, and G. H. Whipple. “HEMOGLOBIN AND PLASMA PROTEIN : THEIR RELATION TO INTERNAL BODY PROTEIN METABOLISM.” The Journal of Experimental Medicine. The Rockefeller University Press, 01 May 1945. Web. 10 Apr. 2017
2.了,美里am, and Mikko Nikinmaa. “More than hemoglobin – the unexpected diversity of globins in vertebrate red blood cells.” Physiological Reports. BlackWell Publishing Ltd, Feb. 2015. Web. 11 Apr. 2017

Image Courtesy:
1. “Myoglobin-1mba”By Opabinia regalis – Self created from PDB entry IMBA using the freely available visualization and analysis package VMD (CC BY-SA 3.0) viaCommons Wikimedia
2.Antibody IgG2″ 由英语维基百科的TimVickers – 從en.wikipedia轉移到共享資源 (Public Domain) viaCommons Wikimedia