偏心和周围反转之间的差异

Thekey differencebetween paracentric and pericentric inversion is thatinparacentric inversion, a chromosomal segment that does not contain thecentromereregion rearranges in reverse orientation, while in pericentric inversion, a chromosomal segment containing the centromere rearranges in reverse orientation.

反转is a type of chromosome rearrangement and a染色体突变. During an inversion, a part of the chromosome breaks and reinserts after turning 180 degrees. Thus, rearrangement occurs in a reversed manner. The broken chromosomal segment has reversed orientation after reinsertion. There are two types of inversions as paracentric inversion and pericentric inversion. Paracentric inversion occurs in one arm of the chromosome while pericentric inversion occurs in both arms.

内容

1.Overview and Key Difference
2.What is Paracentric Inversion
3.What is Pericentric Inversion
4.偏心和上十大反演之间的相似之处
5.并排比较 - 表面形式的偏心vs腹膜倒置
6.概括

什么是偏心反转？

Paracentric inversion is one of the two types of chromosomal inversions. It occurs in one arm of the chromosome. Since both breaking points are present in one arm, this inversion does not include the centromere. Furthermore, the broken segment of the chromosome is rearranged in reverse orientation, as shown in the following figure.

What is Pericentric Inversion?

Pericentric inversion is the second type of chromosomal inversion. It occurs in both arms of the chromosome. Since there is a breaking point in each arm, the breakage occurs in both sides of the centromere. Thus, pericentric inversion includes the centromere.

如上图所示，在上十二倒置期间，包括丝粒重排在内的部分相反。

What are the Similarities Between Paracentric and Pericentric Inversion?

• Paracentric and pericentric inversions are the two main types of inversions.
• Both are also large scale chromosomal mutations.
• 它们发生在单个染色体内。
• Moreover, both types of inversions do not cause a loss of genetic information.
• They simply rearrange the linear gene sequence of a chromosome.

占地和上述倒置之间有什么区别？

Paracentric inversion does not include the centromere, and both breaks occur in one arm of the chromosome while pericentric inversion includes the centromere, and there is a breakpoint in each arm. So, this is the key difference between paracentric and pericentric inversion.

Below infographic summarizes the difference between paracentric and pericentric inversion.

概括– Paracentric vs Pericentric Inversion

反转is a large scale chromosomal mutation. Inversion reverses the orientation of a chromosomal segment after its breakage. Paracentric and pericentric inversion are two types of inversions. Paracentric inversion does not include the centromere region while pericentric inversion occurs in a chromosome segment, including the centromere region. Therefore, this is the key difference between paracentric and pericentric inversion. Moreover, both breaking points lie in one arm of the chromosome in paracentric inversion while there is a breaking point in each arm of the chromosome in pericentric inversion.

Reference:

1.“Chromosomal Inversion.” Wikipedia, Wikimedia Foundation, 3 Aug. 2019,Available here.