Difference Between Naproxen and Naproxen Sodium

Naproxen vs Naproxen Sodium

正如两者一样，萘普生和萘普生钠在相同条件下被规定了NSAID，知道有所不同ence萘普生和萘普生钠是一亩t for health professionals. Naproxen and naproxen sodium belong to the drug class, non-steroidal anti-inflammatory drugs (NSAIDs), which are mostly used to treat the patients with inflammatory conditions. The signs and thesymptomsof aninflammationare pain, heat, redness, swelling and loss of function. An inflammation is not an illness. It is a protective step by the body to remove the infectious substances. NSAIDs treat the inflammatory conditions and the low fever conditions. These drugs act to reduce the process of blood clotting. NSAIDs should be used with caution in patients with high blood pressure,asthma，肾脏失败和肾功能障碍。NSAIDS干扰环氧合酶，COX-1和COX-2的作用以防止炎症。因此，服用NSAID可能会引起胃刺激和肾功能障碍。患者需要调整剂量heart failures。NSAIDs inhibiting cox-2 enzymes are used to treat conditions likerheumatoid arthritis。最近进行的研究表明，NSAID对骨骼愈合过程的作用延迟。萘普生和萘普生钠几乎相似，但有一些差异，因为萘普生钠具有附着的钠部分。

Naproxen – Use, Side Effects, Precautions

Naproxen is an NSAID and reduces pains and the signs of the inflammations. Naproxen should be used with caution in patients having cardiac diseases, kidney diseases and known hypersensitivities to aspirin or other NSAIDs. Naproxen is not suitable for patients who have a history of recent bypass surgery. Naproxen may lead to intestinal bleeding. Taking naproxen during the first and last trimester of pregnancy may produce harmful defects on the unborn baby. Breast feeding mothers should not take naproxen. Safe use of naproxen in children under two years has not been recommended.

Naproxen Sodium – Use, Side Effects, Precautions

Naproxen sodium is an NSAID as naproxen. It interferes with the important mechanisms of the substances that lead to inflammation. Taking naproxen in an empty stomach is not suitable. Patients should not lie down at least ten minutes after taking naproxen sodium. The therapy should be as short as possible. It is better to take the possible lowest dose of naproxen sodium enough to gain the maximum therapeutic effect. Patients with cardiac diseases, kidney diseases and allergic reactions should inform the doctor before taking the drug. Using the drug during the first and last trimester of pregnancy and lactation is not suitable.

What is the difference between Naproxen and Naproxen Sodium?

• Both drugs are NSAIDs and prescription only medicines.

• The chemical name of naproxen is (s)-6-methoxy-α-methyl-2-naphthalene acetic acid. The chemical name of naproxen sodium is (s)-6-methoxy-α-methyl-2-naphthalene acetic acid sodium salt.

• 萘普生和萘普生钠的分子公式为c₁₄H₁₄O₃and C₁₄H₁₃Nao₃, respectively.

• The solubility of naproxen sodium in water is higher than naproxen. Naproxen sodium is freely soluble in water at pH 7 while naproxen is freely soluble in water at high pHs.

• 萘普生片剂的摄取因素是微晶纤维素，croscarmellose钠，氧化铁，povidone和硬脂酸镁。除这些成分外，萘普生钠片剂具有滑石作为成分。

• Absorption of naproxen sodium is higher than that of naproxen.

• Naproxen sodium has a fast onset of action than naproxen.

• 医生开出两种药物，以缓解类风湿关节炎，骨关节炎，脊椎炎，少年关节炎，肌腱炎，毛刺性，急性痛风，疼痛管理，疼痛管理和原发性痛经的体征和症状。

• Both naproxen and naproxen sodium may interact with ACE inhibitors, antacids, sucralose , aspirin, cholestyramine, diuretics, lithium, methotrexate, warfarin and selective serotonin reuptake inhibitors. Both drugs should be stored in well closed containers.

Naproxen and naproxen sodium are prescription only medicines. Physicians, pharmacists and patients should be aware not only of the benefits but also of the possible serious side effects. Naproxen and naproxen sodium should not be used as a practice. The therapy should be as short as possible.

Further Reading:

1. 萘普生和布洛芬之间的差异