不同ce Between Chondroblasts and Chondrocytes

Key Difference – Chondroblasts vs Chondrocytes

Cartilageis a specialized connective tissue found in many places of the body.Chondrogenesisis the process which forms cartilage from mesenchyme tissue. There are two main cell types in the cartilage known as chondroblasts and chondrocytes. Chondroblasts are actively dividing immature cells which form extracellular matrix and the chondrocytes. Chondrocytes are the differentiated cells which are involved in the diffusion of the nutrients, maintenance, and repair of the extracellular matrix of the cartilage. The key difference between chondrocytes and chondroblasts is thatchondroblasts are immature cartilage cells found near the perichondrium while chondrocytes are mature cartilage cells found embedded within the extracellular matrix.

内容
1.Overview and Key Difference
2.什么是软骨细胞
3.什么是软骨细胞
4.并排比较 - 软骨细胞与软骨细胞
5.概括

什么是软骨细胞?

软骨细胞，也称为chondroplasts是未成熟的细胞，对于软骨发育至关重要。它们位于perichondrium的软骨边缘，细胞分裂作为两个对立区域出现。软骨细胞也被称为围骨细胞或间充质祖细胞，这些细胞会产生细胞外基质的软骨细胞和成分。软骨细胞主要分泌两型胶原蛋白和其他类型的细胞外基质成分。

什么是软骨细胞？

Chondrocytes are specialized cells found in the cartilage matrix cavities called lacunae. They are matured and differentiated cells of chondroblasts. The major function of the chondrocyte is to synthesis, maintain and remodel the extracellular matrix of the cartilage. Extracellular matrix is composed of equal proportions of collagen fibrils and proteoglycans. These two components are produced by the chondrocytes in the cartilage. However, chondrocytes are relatively inert cells with low regenerative capacity.

Cartilage does not have blood vessels or nerves. Therefore, to maintain the structure and function of the cartilage, chondrocytes should obtain nutrients from the matrix. Nutrients are supplied to the chondrocytes by a process calleddiffusion。Chondrocytes malfunction can lead to a disease calledosteoarthritis。It is a cartilage degenerative disease caused due to the breakage of tissuehomeostasis。

软骨的灵活性取决于软骨中存在的软骨细胞数量。如图03所示，有三种称为透明质酸的软骨，弹性和纤维状油脂。

What is the difference between Chondroblasts and Chondrocytes?

软骨细胞vs Chondrocytes
软骨细胞are a type of cells found in the cartilage which are responsible for the cartilage development.	软骨细胞是软骨维护的一种专门细胞。
地点
These are located in the two oppositional growing areas of the cartilage under the perichondrium	这些被发现嵌入在空隙中。
Maturity
These are immature cells which are actively dividing.	These are immature cells which are inactive and differentiated.
Usage
软骨细胞产生软骨的软骨细胞和细胞外基质。	Chondrocytes produce components of the extracellular matrix and maintain the cartilage structure and function.
Chondrocyte Formation
这些是软骨细胞的祖细胞	软骨细胞由软骨细胞形成

摘要 - 软骨细胞和软骨细胞

软骨细胞and chondrocytes are two types of cells found in the cartilage. Chondroblasts are actively dividing immature cells located near the perichondrium of the cartilage. They are the actual cells which create the cartilage. Chondroblasts are the progenitors of the chondrocytes and extracellular matrix of the cartilage. When chondroblasts are embedded in the cartilage matrix and cease dividing, they become chondrocytes. Chondrocytes are the specialized mature cells found in the cartilage which produces and manages the cartilage matrix. Chondrocytes are composed of collagen fibrils and proteoglycans and responsible for the flexibility of the cartilage. This is the difference between chondroblasts and chondrocytes.

Reference:
1.Lefebvre, Véronique, and Patrick Smits. “Transcriptional control of chondrocyte fate and differentiation.” Birth Defects Research Part C: Embryo Today: Reviews. Wiley Subscription Services, Inc., A Wiley Company, 26 Sept. 2005. Web. 07 Mar. 2017.
2.Zhang，Minjie，Sriniwasan B. Mani，Yao HE，Amber M. Hall，Lin Xu，Yefu Li，David Zurakowski，Gregory D. Jay和Matthew L. Warman。“诱导的浅表软骨细胞死亡可减少创伤后骨关节炎的分解代谢软骨损伤。”临床研究杂志。美国临床调查学会，2016年8月1日。2017年3月7日。

Image Courtesy:
1.”Diagram of cartilage cells called chondroblasts CRUK 032″ By Cancer Research UK – Original email from CRUK(CC BY-SA 4.0)viaCommons Wikimedia
2. “Elastic cart 100X” By Ganímedes – Own work(CC BY-SA 3.0)viaCommons Wikimedia
3. “412 Types of Cartilage-new” By OpenStax College – Anatomy & Physiology,联系网站。2013年6月19日。(CC BY 3.0)viaCommons Wikimedia