Key Difference – Microarray vs RNA Sequencing Transcriptome represents the whole content of RNA present in a cell including mRNA, rRNA, tRNA, degraded RNA, and, nondegraded RNA. Profiling transcriptome is an important process in order to understand the cell insights. There are several advanced methods for transcriptome profiling. Microarray and RNA sequencing are two […]
Key Difference – SYBR Green vs Taqman SYBR Green and Taqman are two methods employed to detect or watch amplification process of real-time PCR. SYBR Green is a method based on intercalating nucleic acid staining dye while Taqman is a method based on hydrolysis probe. Both technologies are designed to generate fluorescence during the […]
Key Difference – Transition vs Transversion It is important to have a general knowledge of base pairing in DNA in order to understand the difference between transition and transversion mutations. There are five different nitrogenous bases in nucleic acids: adenine (A), guanine (G), cytosine (C), thymine (T) and uracil (U). First two bases (A […]
Key Difference – DNA Damage vs Mutation DNA bears the genetic information of each cell. It is stored with the heredity information which is supposed to be passed from one generation to the next generation. The genetic information is hidden within the DNA molecules in the form of precise nucleotide sequences. There are billions […]
Key Difference – DNA vs DNAse DNA is a nucleic acid found mainly in the nucleus of cells. It carries genetic information of the cells which are essential for growth, development, metabolism and reproduction of organisms. DNA molecule is composed of deoxyribonucleotides arranged in long chains. DNAse is an enzyme that is able to […]
Key Difference – DNA Ligase vs DNA Polymerase DNA ligase and DNA polymerase are important enzymes involved in DNA replication and DNA repair mechanisms of organisms. DNA ligase is responsible for joining DNA fragments by catalyzing the formation of phosphodiester bonds between nucleotides. DNA polymerase is responsible for synthesis of DNA from its building […]
Key Difference – Endonuclease vs Exonuclease Before looking at the difference between endonuclease and exonuclease, it is important to know what exactly a nuclease is. A nuclease is an enzyme capable of cleaving phosphodiester bonds between nucleotides in nucleic acids. Endonuclease and exonuclease are two classifications of nucleases. The key difference between endonuclease and […]
Key Difference – Mismatch Repair vs Nucleotide Excision Repair Tens and thousands of DNA damages occur in the cell per day. It induces changes to the cell processes such as replication, transcription as well as the viability of the cell. In some cases, mutations caused by these DNA damages may lead to deleterious diseases […]
Key Difference – Type 1 vs 2 Collagen Collagen is a fibrous protein found in connective tissues, skin, bone, etc. It provides strength and firmness to various parts of the body. Collagen has a complex structure composed of three polypeptide chains packaged into triple helix configuration. There are different types of collagen proteins found […]
Key Difference – DNA Polymerase 1 vs 2 vs 3 DNA polymerase is a special clade of enzymes which are involved in DNA replication of living organisms. Genetic information is passed from one generation to the next generation due to the presence of this enzyme. There are different forms of DNA polymerase enzyme found […]
