Thekey difference between sympathomimetic and sympatholytic drugsis that sympathomimetic drugs are drugs that can enhance adrenergic function, whereas sympatholytic drugs are drugs that can interrupt adrenergic function.
The term adrenergic refers to the interaction between proteins and drugs with adrenaline or noradrenaline, respectively. Adrenergic drugs are medications that can stimulate the nerves in our body’s交感神经系统.
内容
1.Overview and Key Difference
2.What is Sympathomimetic Drug
3.什么是交感药
4.Sympathomimetic vs Sympatholytic Drug in Tabular Form
5.Summary – Sympathomimetic vs Sympatholytic Drug
What is Sympathomimetic Drug?
Sympathomimetic drugs are a type of adrenergic drug that is used as a stimulant compound showing effects of endogenous agonists of the sympathetic nervous system. These drugs are also known as肾上腺素药或者肾上腺素胺. These drugs are important in treating心脏骤停and low blood pressure. They can also treat delay premature labour conditions.Moreover, there are several mechanisms through which these drugs can act. Some of these mechanisms include direct activation of postsynaptic receptors, blocking, breaking down and re-up taking of certainneurotransmitters,刺激生产和释放catecholamines. Among these mechanisms, direct-acting occurs through alpha-adrenergic agonists, beta-adrenergic agonists, and dopaminergic agonists. The indirect action occurs through MAOIs, COMT inhibitors, release of stimulants, etc.
Some examples of sympathomimetic drugs include amphetamine, benzylpiperazine, cathine, cathinone, cocaine, ephedrine, maprotiline, MDMA, and methcathinone.
什么是交感神经药?
阻滞交感神经的药物是一种肾上腺素能药物that can oppose the downstream effects of postganglionic nerve firing. These nerve firings occur in effector organs that are innervated by the sympathetic nervous system. Moreover, these drugs can be used as antihypertensives, as medication to treat anxiety, including generalized anxiety disorder and panic disorder.
When considering the mechanism of action, these drugs can inhibit the signals of epinephrine and norepinephrine, inhibit theadrenergic receptorsignalling through blocking the synthesis of catecholamines, by inhibiting VMAT, and being toxic to sympathetic neurons, etc.
该药物的使用包括神经节阻塞,外围表演,中央作用,通过充当β受体阻滞剂等焦虑等。交感神经也称为sympathoplegic drugs.
交感神经和交感神经药有什么区别?
肾上腺素药是可以刺激人体交感神经系统中神经的药物。交感神经和交感神经药物之间的关键区别在于,交感神经药物是可以增强肾上腺素功能的药物,而交感神经药物是可以中断肾上腺素能功能的药物。苯丙胺,苯二哌嗪,大教堂,马可酮,可卡因,麻黄碱,maprotiline,mDMA和甲苯二苯酮是交感神经药物的一些例子,而丙氨酸,肾上腺素,利利氨基氨基胺,麦克氨基氨基氨基酶,甲虫素,葡萄膜酶,和葡萄膜胺,肾上腺素,卵巢氨基氨基氨基氨基氨基氨基氨基氨基氨基氨基酶,和甲基苯胺。
Moreover, the sympathomimetic drugs act by direct activation of postsynaptic receptors, blocking, breaking down and re-up taking of certain neurotransmitters, and stimulation of production and release of catecholamines. Meanwhile, sympatholytic drugs act via the inhibition of the signals of epinephrine and norepinephrine, inhibition of adrenergic receptor signaling through blocking the synthesis of catecholamines, by inhibition of VMAT, by being toxic to sympathetic neurons, etc.
以下信息图列出了与表格形式的交感神经和交感神经药物之间的差异
摘要 - 交感神经与交感神经药物
肾上腺素药是可以刺激人体交感神经系统中神经的药物。交感神经和交感神经药物之间的关键区别在于,交感神经药物是可以增强肾上腺素功能的药物,而交感神经药物是可以中断肾上腺素能功能的药物。
Reference:
1. Cafasso, Jacquelyn. “Adrenergic Drugs: Types, Uses, and Effects.”Healthline, Healthline Media, 28 Aug. 2018.
Image Courtesy:
1.“”Blausen 0838 Sympathetic Innervation” Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. – Own work(CC BY 3.0)via Commons Wikimedia
2. “Tablets pills medicine medical waste” By Pöllö – Own work(CC BY 3.0)via Commons Wikimedia
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