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结核分枝杆菌和牛分枝杆菌有什么区别

2021年8月6日Posted byDr.Samanthi

Thekey difference betweenMycobacterium tuberculosis和Mycobacterium bovisis thatMycobacterium tuberculosis只感染人类而Mycobacterium bovis感染人类和家畜。

Mycobacterium tuberculosis和Mycobacterium bovis是在属下分类的两个物种Mycobacterium。Mycobacteriumis a genus of Actinobacteria. There are over 190 species in this genus. Some species of this genus are pathogens that cause serious diseases in mammals, includingtuberculosis和leprosy in humans. They tend to grow in a mold-like fashion on the surface of cultures. They areacid-fast and cannot be stained by the gram stain procedure。一些我的基因组cobacteria are quite large when compared to other known bacteria.

内容

1.Overview and Key Difference
2.What isMycobacterium Tuberculosis
3.What isMycobacterium Bovis
4.Similarities –Mycobacterium Tuberculosis和Mycobacterium Bovis
5.Mycobacterium TuberculosisvsMycobacterium Bovis以表格形式
6.Summary –Mycobacterium TuberculosisvsMycobacterium Bovis

What isMycobacterium Tuberculosis?

Mycobacterium tuberculosisinfects only humans and causes tuberculosis. It is a species of pathogenic bacteria in the family of Mycobacteriaceae and was discovered in 1882 by Robert Koch. It has an unusual waxy coating on its cell surface, usually due to the presence of mycolic acid. Particularly, this coating makes the bacterial cells impervious to gram staining. Therefore, acid-fast stains such as Ziel-Neelsen and fluorescent stains such as auramine are primarily used to identifyM. tuberculosis在实验室。基因组M. tuberculosis(H37Rv strain) was sequenced and published in 1998. The genome contains approximately 4 million base pairs and 3959 genes.

Mycobacterium Tuberculosis vs Mycobacterium Bovis

Figure 01: Mycobacterium tuberculosis

This bacterium is highly aerobic and needs high levels of oxygen. Hence, it is a pathogen of the human respiratory system and infects the lungs. Tuberculosis is the disease caused afterM. tuberculosisinfects the lungs. This disease has symptoms such as persistent cough, weight loss, night sweat, high temperature, tiredness, loss of appetite, and swelling in the neck. The most frequently used diagnostic methods for tuberculosis are tuberculin skin test, acid-fast staining, culture, and polymerase chain reaction. BCG vaccine has limited success in preventing tuberculosis.

What isMycobacterium Bovis?

Mycobacterium bovisinfects both humans and domestic animals, causing tuberculosis in both humans and domestic animals such as cattle. It is a slow-growingaerobic bacteriumin the family of Mycobacteriaceae. Moreover,M. boviscan jump the species barrier and cause tuberculosis like infections in humans and other mammals.Mycobacterium bovisis the ancestor of the most widely applied vaccine against tuberculosis. This vaccine is termed BCG (Mycobacterium bovisbacille Calmette Guerin). The genome ofMycobacterium Bovisis approximately 4.3 Mb with 4200 genes.

Compare Mycobacterium Tuberculosis and Mycobacterium Bovis

Figure 02:Mycobacterium Bovis

牛结核病的症状类似于人类结核病,包括体重减轻,发烧,汗水和持续的咳嗽。除了牛外,其他牲畜,例如麋鹿,鹿,野牛,山羊和猪,还可以获得牛结核病。抗生素,异烟肼和利福平成功控制牛结核病。

之间有什么相似之处Mycobacterium Tuberculosis和Mycobacterium Bovis?

  • tuberculosis和M. bovisare two species of the genusMycobacterium。
  • These bacteria are rod-shaped and aerobic.
  • Both bacteria cause tuberculosis.
  • They cause similar symptoms such as weight loss, fever, night sweats, and a persistent cough.
  • Both bacteria are slow-growing.
  • They are both can be identified through acid-fast staining.
  • BCG vaccine can treat tuberculosis caused by both.

What is the Difference BetweenMycobacterium Tuberculosis和Mycobacterium Bovis?

Mycobacterium tuberculosis只感染人类,而Mycobacterium bovis感染人类和家畜。因此,这是Mycobacterium tuberculosis和Mycobacterium bovis。此外,分枝杆菌tuberculosishas a genome of 4.4 Mb with 3959 genes, whileMycobacterium bovishas a genome of 4.3 Mb with 4200 genes.

The following infographic tabulates more differences betweenMycobacterium tuberculosis和Mycobacterium bovisfor side by side comparison.

Summary –Mycobacterium TuberculosisvsMycobacterium Bovis

Mycobacteriumis a genus of肌动杆菌其中包含家庭Mycobacteriaceae。Mycobacterium tuberculosis和Mycobacterium bovisare two species classified under genusMycobacterium和家人分枝杆菌科。Mycobacterium tuberculosis仅感染人类在人类中引起结核病。相比之下,Mycobacterium bovisinfects both humans and domestic animals and causes bovine tuberculosis. Thus, this is the summary of the difference betweenMycobacterium tuberculosis和Mycobacterium bovis。

Reference:

1.“Mycobacterium Tuberculosis。” An Overview | ScienceDirect Topics.
2. “Mycobacterium Bovis。” An Overview | ScienceDirect Topics.

Image Courtesy:

1.“”结核分枝杆菌细菌(16843981465)” By NIAID – Mycobacterium tuberculosis Bacteria(CC由2.0)via Commons Wikimedia
2. “Mycobacterium bovis BCG ZN” By Y tambe – Y tambe's file(CC BY-SA 3.0)via Commons Wikimedia

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Filed Under:Bacteriology

About the Author:Dr.Samanthi

Samanthi Udayangani博士拥有B.Sc.植物科学学位,硕士在分子和应用微生物学和应用微生物学中的博士学位。她的研究兴趣包括生物肥料,植物 - 微生物相互作用,分子微生物学,土壤真菌和真菌生态学。

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