狼疮和Sjogren综合征有什么区别|比较类似术语之间的差异

Thekey difference在狼疮和Sjogren综合征之间is that lupus is anautoimmune disease这主要影响关节，皮肤，肾脏，血细胞，脑，心脏和肺部，而Sjogren综合征是一种自身免疫性疾病，主要影响泪液和唾液产生glands, nose, throat, skin, and vagina.

狼疮和Sjogren综合征是两种不同类型的自身免疫性疾病。自身免疫性疾病是一种医学疾病，其中免疫系统错误地攻击了自己的身体细胞。在自身免疫性疾病期间，免疫系统无法区分外国细胞和自身的身体细胞。因此，它释放了称为的蛋白质autoantibodiesto attack healthy cells.

内容

1.Overview and Key Difference
2.什么是狼疮
3.什么是Sjogren综合征
4.相似之处 - 狼疮和Sjogren综合征
5.Lupus vs Sjogren’s Syndrome in Tabular Form
6。Summary – Lupus vs Sjogren’s Syndrome

什么是狼疮?

红斑狼疮是一种自身免疫性疾病,主要影响joints, skin, kidneys, blood cells, brain, heart, and lungs in the body. The inflammation caused by lupus can affect many different body systems. Lupus is often difficult to diagnose because its signs and symptoms mimic those of other ailments. Moreover, no two cases of lupus are exactly alike. These signs and symptoms may come on suddenly or may develop slowly, may be mild or severe, and also may be temporary or permanent.

Lupus vs Sjogren's Syndrome in Tabular Form

图01：狼疮

However, the most distinctive sign of lupus is a facial rash, which resembles the wings of a butterfly. This rash normally infolds across both cheeks. The other signs and symptoms may include fatigue, fever, joint pain, skin lesions that appear or worsen with sunlight, fingers, and toes that turn white or blue, shortness of breath, chest pain, dry eyes, headaches, confusion, and memory loss. Lupus can be diagnosed through physical examination, a combination of blood and urine tests, including complete blood count, erythrocyte sedimentation rate, kidney, and liver assessment, urinalysis, antinuclear antibody (ANA) test, imaging tests (X-ray, echocardiogram), and skin biopsy. Furthermore, treatments are provided for lupus through medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarial drugs (hydroxychloroquine), corticosteroids, immunosuppressants (azathioprine, mycophenolate, methotrexate, cyclosporine), and biologics (belimumab, rituximab).

Sjogren综合征是什么？

Sjogren的综合征是一种自身免疫性疾病，主要影响体内泪液和产生唾液的腺体，鼻子，喉咙，皮肤和阴道。在极少数情况下，Sjogren综合征会影响肝脏，肾脏或肺部。女性通常比男性综合症更受到男性影响。发病的平均年龄约为45至55岁。

Figure 02: Sjogren’s Syndrome

The signs and symptoms may include dry mouth, dry or burning eyes, a sensation of grittiness in the eyes, swelling of glands around the neck or the head, trouble swallowing, irritation of the esophagus and acid reflux, fatigue, joint pain, rashes, inflammation of the lungs, and problems with liver or kidney functioning. This autoimmune disease can be diagnosed through blood and urine tests, Schirmer’s tests for tear glands, ocular surface staining for eyes, salivary gland function scans, a biopsy of lips, sialometry, which measures the flow of saliva, and ultrasonography of the major salivary glands. Furthermore, treatment options for Sjogren’s syndrome may include eye drops to keep eyes moist, gum, lozenges, saliva substitutes, drugs that help the mouth produce more saliva, antibiotics, antifungal medications, irrigation for dry noses, acid reflux drugs (proton pump inhibitors, H2 blockers), and steroids to suppress the immune system.

狼疮和Sjogren综合征之间有什么相似之处？

狼疮和Sjogren综合征是两种不同类型的自身免疫性疾病。
Lupus and Sjogren’s syndrome can occur together.
Women are affected mostly by both diseases.
遗传学和环境因素引发了两种自身免疫性疾病。

What is the Difference Between Lupus and Sjogren’s Syndrome?

红斑狼疮是一种自身免疫性疾病,主要影响joints, skin, kidneys, blood cells, brain, heart, and lungs in the body, while Sjogren’s syndrome lupus is an autoimmune disease that mainly affects tear and saliva producing glands, nose, throat, skin, and vagina in the body. Thus, this is the key difference between lupus and Sjogren’s syndrome. Furthermore, the average age of the onset of lupus is around 15 to 45 years old, but the average age of the onset of Sjogren’s syndrome is around 45 to 55 years old.

The below infographic presents the differences between lupus and Sjogren’s syndrome in tabular form for side by side comparison.

Summary – Lupus vs Sjogren’s Syndrome

狼疮和Sjogren综合征是两种不同类型的自身免疫性疾病。Often, lupus and Sjogren’s syndrome can occur together. Lupus mainly affects joints, skin, kidneys, blood cells, brain, heart, and lungs in the body, while Sjogren’s syndrome mainly affects tear and saliva producing glands, nose, throat, skin, and vagina in the body. So, this is the key difference between lupus and Sjogren’s syndrome.

Reference:

1.“”Lupus.” Mayo Clinic, Mayo Foundation for Medical Education and Research.
2. Robinson, Kara Mayer. “Sjogren’s Syndrome: Symptoms, Causes, Diagnosis, Treatment.” WebMD.