登革热IgG IgM和NS1有什么区别

这关键区别between dengue IgG IgM and NS1是从3种暴露于登革热病毒中完全检测到IgG^路从7月检测到IgM的一周可接触到24周^Thday of exposure up to 24 weeks and NS1 is detectable from the 1^英石day up to the 7^Th暴露日。

登革热病毒是单链RNA virusFlaviviridae家族是蚊子传播的。到目前为止，已经发现了登革热病毒的四种血清型。在检测登革热病毒期间，IgG，IgM和NS1发挥了重要作用。登革热特异性I​​gM和IgG是最常见的诊断方法。

CONTENTS

1。概述和关键差异
2。什么是登革热IgG
3。什么是登革热IGM
4。What is Dengue NS1
5.相似性 - 登革热IgG IgM和NS1
6.登革热IgG vs igm vs ns1以表格形式
7.摘要 - 登革热IgG vs IgM vs NS1

什么是登革热IgG?

IgG is immunoglobulin G found in blood and lymph that is produced and released by plasma B cells. IgG antibodies represent 75 % of serum antibodies in humans. The complete development of IgG antibodies occurs after three weeks following exposure in immunocompetent individuals. However, IgG is detectable from the 3^路症状日，可能会在感染后长达6个月。与登革热病毒相关的IgG抗体的产生与急性相感染一致。

在没有感染的情况下，未检测到IgM抗体。但是，由于人体对登革热病毒产生IgG抗体之前，这可能是假阴性的。因此，如果个人仍然怀疑登革热病毒，则在暴露后10-12天后应分析第二个样本。用于检测IgG抗体的测试为IgGELISA。Positive results indicate the presence of the dengue virus. False positives could also indicate the presence of other types of viruses such asZika virus，，，，West Nile virus，，，，Flavivirus, etc. In such instances, it is vital to obtain a detailed history of the patient followed by further laboratory testing.

什么是登革热IGM？

IgM是血液和淋巴液中发现的免疫球蛋白M。它是新感染过程中人体产生的第一抗。IgM是人体产生的几种类型的抗体，用于诱导感染的免疫反应。在登革热感染期间，登革热病毒特异性IgM和其他中和抗体是在症状的第一周结束后产生的。它们不是在症状的前七天生产的。5之后可以检测到IgM^Th暴露日。IgM级别通常是可变的。它们完全存在于感染的第七天，并且可能会在发病后12周持续存在超过12周的症状。

在血清型测定过程中，IgM抗体不是至关重要的。登革热MAC-ELISA（IGM抗体捕获酶连接的免疫吸附测定法）是对登革热病毒的质性检测的测试。在测试过程中，MAC ELISA使用抗人IgM抗体捕获人IgM抗体，并添加登革热病毒抗原。两种样品类型用于登革热IGM测试。它们是血清和脑脊液。Mac ELISA的测试结果可能为负或阳性。阳性IgM测试结果将患者分类为推定或最近感染的人。负IgM结果复杂，应通过NAAT（核酸扩增测试）重新装修，以确认存在或不存在登革热IgM抗体。登革热IgM检测套件可商购。

What is Dengue NS1?

Dengue NS1 is a protein secreted into the blood during dengue infection. This is a non-structural protein detected during the acute phase of dengue infection. The NS1 test detects the NS1 protein and is developed for use in blood serum. This test use antibodies synthetically labelled to detect the protein NS1. These tests have a high sensitivity rate during the first seven days of symptoms. NS1 tests are not recommended after the 7^Th症状日由于测试的敏感性将降低并提供错误的结果。

在结果分析过程中，阳性NS1测试表明存在登革热感染，但没有血清型。获得血清型信息对于患者护理并不重要。但是，这对于监视目的很重要。登革热NS1蛋白存在于全血或血浆中。作为临床规范，在血清样品中开发，进行，进行和评估了登革热NS1测试。

During the dengue NS1 test, the diagnostic result is obtained with the combination of dengue IgM antibody. This is for the first seven days of symptoms. If both antigen and antibody tests are negative, a second specimen from the recovering phase should be obtained and tested for IgM. Dengue NS1 test provides two types of results as negative and positive test results. During a positive test result, the test confirms the presence of dengue infection. During a negative test result, the test does not rule out the probability of dengue infection. Hence, the test is performed with the presence of dengue IgM antibodies. This will confirm if there is any dengue exposure in the patient. Dengue NS1 test kits are commercially available.

What are the Similarities Between Dengue IgG IgM and NS1?

• All three IgG, IgM and NS1 are diagnostic tools for the detection of the dengue virus.
• All three are present in the blood following exposure to the dengue virus.
• IgG IgM和NS1测试分析使用血清作为样品。
• 这re are commercial test kits for the detection of all three types.
• IgG, IgM and NS1 based dengue virus tests are significantly accurate than other tests to detect dengue virus.

登革热IgG IgM和NS1有什么区别？

这关键区别between dengue IgG IgM and NS1 is their detectable periods upon infection. Dengue IgG is completely detectable after the 3^路在7期间检测到登革热IgM时暴露的一周^Thday up to 24 weeks of post-exposure. Meanwhile, dengue NS1 detection is critical since it has to be done during the first 07 days of exposure. IgG and IgM are antibodies.

下面的信息图列出了登革热IgG IgM和NS1以表格形式进行比较。

摘要 - 登革热IgG vs IgM vs NS1

Dengue virus is a mosquito borne, single-stranded RNA virus of the family Flaviviridae. Dengue IgG, IgM and NS1 play a major role in detecting dengue and are the most accurate test subjects. IgG is immunoglobulin G found in blood and lymph produced and released by plasma B cells. IgG is detectable from the 3^路天的症状和可能保持6个月infection. IgM is immunoglobulin M found in blood and lymph fluid, and it is the first antibody produced by the body during a new infection. They are detected on the 7th day of infection and may persist more than 12 weeks post symptom onset. Dengue NS1 is a protein secreted into the blood during dengue infection. NS1 tests are not recommended after the 7^Th症状日由于测试的敏感性将降低并提供错误的结果。This summarizes the difference between dengue IgG IgM and NS1 IgG IgM and NS1.

参考：

1。“登革热病毒抗原检测。”疾病预防与控制中心，2019年5月3日。
2.“”Test ID: DENGM Dengue Virus Antibody, IGG and IGM, Serum。”Mayo Clinic Labs。

图片提供：

1。“Dengue testing” By James Heilman, MD – Own work(CC BY-SA 3.0)via Commons Wikimedia
2.“”登革热病程”格雷厄姆·胡克（Graham Beards）博士 - 自己的工作(CC BY-SA 3.0)via Commons Wikimedia
3.“”SAG Dengue-Virus 160413 01” By Girish Khera,科学动画– (Public Domain) via Commons Wikimedia