这关键区别在补偿和代偿性肝硬化之间是补偿肝硬化是肝硬化的无症状阶段,而肝肝硬化是代表性的,是肝肝硬化的有症状阶段。
肝肝硬化导致逐步替代健康的肝脏cells with scar tissues. Cirrhosis normally happens over a long period of time due to infections or alcohol addiction. Cirrhosis is the end stage of any chronic liver disease. There are two different clinical stages of cirrhosis as compensated and decompensated. Compensated liver cirrhosis is the initial stage, while decompensated liver cirrhosis is the more complicated stage.
CONTENTS
1。概述和关键差异
2。What is Compensated Liver Cirrhosis
3。What is Decompensated Liver Cirrhosis
4。Similarities – Compensated and Decompensated Liver Cirrhosis
5。补偿的与表格形式的肝肝硬化的代偿率代偿
6.Summary – Compensated vs Decompensated Liver Cirrhosis
What is Compensated Liver Cirrhosis?
Compensated liver cirrhosis is the asymptomatic stage of liver cirrhosis. If someone has compensated cirrhosis, they won’t show any symptoms. But in rare cases, some symptoms like itching, fatigue, loss of appetite, stomach, weight loss, bruising, swelling/retaining fluid in the legs or abdominal area, confusion, and loss of muscle mass come out. At this stage, the liver still carries out its function because there are healthy cells to take up for the damaged cells and scar tissues caused by cirrhosis. Therefore, people who are suffering from compensated liver cirrhosis can stay in this stage for many years. A more complicated stage called decompensated cirrhosis comes after compensated cirrhosis. However, there is potential reversibility from decompensated to the compensated stage.
静脉曲张的存在是补偿患者的关键预后因素,并表明代偿性的可能性更高。此外,肝硬化的患者的中位生存时间> 12年。由于患者可能缺乏临床,实验室和放射学发现,因此诊断为补偿肝硬化更具挑战性。他们可能需要活检进行诊断。
补偿肝肝硬化的管理选择可能包括基础疾病的治疗(抗病毒治疗的治疗HBV和HCV, abstinence from alcohol), screening for varices (prevention of varices haemorrhage), screening for hepatocellular carcinoma, and prevention of decompensation (complete alcohol abstinence, obesity management, careful dosing and selection of drugs, appropriate vaccination, not avoiding statins, optimizing control of diabetes mellitus).
什么是代偿性肝硬化?
Decompensated liver cirrhosis is the symptomatic stage of liver cirrhosis. Cirrhosis normally does not show any symptoms at the earlier stages. However, as it progresses to decompensated liver cirrhosis, it can cause symptoms such asjaundice,疲劳,体重减轻,容易出血和瘀伤,由于液体积累,腿部肿胀,混乱,言语或嗜睡,腹部肿胀,恶心,食欲不振,spider veins,手掌上的发红,睾丸收缩,男性乳房生长以及无法解释的瘙痒。诊断出代偿性肝硬化的诊断更容易,可以通过患者病史,体格检查,成像测试(CT扫描,MRI和超声检查)和实验室发现(血液检查)进行。
代偿肝肝硬化的管理选择可能包括遵循低盐饮食,不使用休闲药或酒精,服用利尿剂,服用抗病毒药物来管理慢性乙型肝炎或C新的药物,服用药物来改善血液流向肝脏,筛查静脉曲张(预防静脉曲张出血),筛查肝细胞癌,腹水(服用利尿剂),脑病(服用利尿剂),使用(使用乳酸糖或利法克萨米蛋白),预防进一步的代替,预防进一步的补偿。死亡,预防复发性静脉曲张出血(β受体阻滞剂和结扎),肝移植和其他复发症状的技巧(完全戒酒,肥胖,肥胖管理,仔细的药物,适当的疫苗接种,适当的疫苗接种,血管舒张剂,使用较低的NSAID,避免使用NSAID,避免使用NSAID,避免使用NSAID,他汀类药物的剂量,优化对糖尿病的控制)。
补偿和代偿性肝硬化之间有什么相似之处?
- Compensated and decompensated liver cirrhosis are the two main stages of liver cirrhosis.
- 两个肝肝硬化阶段的原因是相同的。
- 在肝肝硬化的两个阶段都可以观察到疤痕组织取代正常的肝细胞。
- Both stages of liver cirrhosis can be managed by antiviral treatment and alcohol abstinence.
补偿和代偿性肝硬化有什么区别?
Compensated liver cirrhosis is the asymptomatic stage of liver cirrhosis, while decompensated liver cirrhosis is the symptomatic stage of liver cirrhosis. Thus, this is the key difference between compensated and decompensated liver cirrhosis. Furthermore, the median survival time of patients with compensated cirrhosis is > 12 years, while the median survival time of patients with decompensated cirrhosis is approximately 2 years.
以下信息图列出了以表格形式进行补偿和代偿性肝硬化之间的差异。
Summary – Compensated vs Decompensated Liver Cirrhosis
Cirrhosis is the scarring of the liver due to long-time liver damage. Compensated and decompensated liver cirrhosis are two stages of liver cirrhosis disease. Compensated liver cirrhosis refers to the asymptomatic stage of liver cirrhosis, while decompensated liver cirrhosis refers to the symptomatic stage of liver cirrhosis. So, this is the key difference between compensated and decompensated liver cirrhosis.
参考:
1. Welch,Connie M.”什么是补偿和代偿性肝硬化?HEP,2020年12月9日。
2。Osborn, Corinne O’Keefe. “肝硬化的代表性:症状,原因,治疗,预期寿命是的。”Healthline,Healthline Media,2018年7月30日。
图片提供:
1。“NAFLD liver progression” By Signimu – Own work(CC BY-SA 3.0)via Commons Wikimedia
2.“描述患有肝病的人”Myupchar(CC BY-SA 4.0)via Commons Wikimedia
Leave a Reply