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What is the Difference Between Beta Alanine and L Alanine

January 26, 2022Posted byDr.Samanthi

Thekey difference在β丙氨酸和L丙氨酸之间is that beta alanine is anon-proteinogenic amino acidwhile L alanine is aproteinogenic amino acid.

Generally,amino acidsare the building blocks of proteins. They combine with each other to form proteins. There are two groups of amino acids as non-proteinogenic and proteinogenic. Non-proteinogenic amino acids are not normally incorporated into proteins during thetranslational process. Some examples of non-proteinogenic amino acids are GABA, L-DOPA, triiodothyronine, and beta alanine. Proteinogenic amino acids, on the other hand, are the amino acids that are incorporated into proteins during translation. In eukaryotes, there are 21 proteinogenic amino acids. Some examples of proteinogenic amino acids are histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, L alanine, valine, etc.

内容

1.Overview and Key Difference
2.What is Beta Alanine
3.What is L Alanine
4.Similarities – Beta Alanine and L Alanine
5.Beta Alanine vs L Alanine in Tabular Form
6.Summary – Beta Alanine vs L Alanine

什么是β丙氨酸?

β丙氨酸是一种非蛋白质生成氨基酸。这是一种天然存在的β氨基酸。在β丙氨酸中,氨基酸组附着在β碳上,而不是更常见的α碳。β丙氨酸的IUPAC名称是3-氨基丙酸。与α丙氨酸不同,β丙氨酸没有立体中心。立体中心是带有不同取代基的分子的任何点。立体中心处任何两个取代基的互换导致立体异构体的形成。

Beta Alanine vs L Alanine in Tabular Form

Figure 01: Beta Alanine

尽管β丙氨酸是一种非蛋白质生成氨基酸,但据说它是按速率限制来的肉豆蔻肽的前体。此外,增加β丙氨酸的量会增加肌肉中肉豆蔻素的总浓度。肌氨酸可以减轻疲劳,并有助于发展更瘦的肌肉。想要发展肌肉的人通常会服用β丙氨酸补充剂,以进一步增加天然β丙氨酸的储存。随着补充β丙氨酸的补充,肌肉中的肌肽浓度最终提高了运动员的肌肉锻炼表现。此外,β丙氨酸也是Anserine(二肽)和泛酸(维生素B)的残基5).

What is L Alanine?

L alanine is a proteinogenic amino acid. The L isomer of alanine is the one that is usually incorporated into proteins. L alanine amino acid is only second to leucine in the rate of occurrence. It was proved that L alanine accounts for 7.8 % of the primary structure in a sample of 1150 proteins. On the other hand, D alanine occurs in only polypeptides in some bacterial cell walls. In L alanine, the amino group of amino acids is attached to the usual α carbon. Moreover, it also has stereoisomers.

β丙氨酸和L丙氨酸 - 并排比较

Figure 02: L Alanine

The IUPAC name of L alanine is 2-aminopropanoic acid. L alanine is a non-essential amino acid. It is normally produced enzymatically from L aspartate using aspartate β decarboxylase. It is the smallest of all amino acids. L alanine has been used as a supplement in cell culture media. Furthermore, L alanine is used as a food additive, an ingredient in infusion solutions, and a precursor for chemical and pharmaceutical products

What are the Similarities Between Beta Alanine and L Alanine?

  • Beta alanine and L alanine are two structurally different amino acids.
  • 它们是天然氨基酸。
  • Both amino acids have the same molecular formula: C3H7NO2.
  • These amino acids have different applications.

β丙氨酸和L丙氨酸有什么区别?

β-丙氨酸是一种非蛋白酶氨基酸,而L丙氨酸是蛋白质氨基酸。因此,这是β丙氨酸和L丙氨酸之间的关键区别。此外,在β-丙氨酸中,氨基酸的氨基酸组附着在β碳上,但是在L丙氨酸中,氨基酸的氨基酸基团附着于α碳。

The below infographic presents the differences between beta alanine and L alanine in tabular form for side by side comparison.

Summary – Beta Alanine vs L Alanine

Amino acids are organic molecules that combine to form proteins. Beta alanine and L alanine are two different amino acids. Beta alanine is a non-proteinogenic amino acid, while L alanine is a proteinogenic amino acid. So, this is the key difference between beta alanine and L alanine.

Reference:

1. McMillen, Matt. “Beta-Alanine: Uses and Risks.” WebMD.
2. “Alpha-Alanine: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews.” WebMD.

Image Courtesy:

1.“”Beta alanine comparison”(CC BY-SA 3.0)via Commons Wikimedia
2. “L-Alanine”(CC BY-SA 3.0)via Commons Wikimedia

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Filed Under:Biochemistry

About the Author:Dr.Samanthi

Dr.Samanthi Udayangani holds a B.Sc. Degree in Plant Science, M.Sc. in Molecular and Applied Microbiology, and PhD in Applied Microbiology. Her research interests include Bio-fertilizers, Plant-Microbe Interactions, Molecular Microbiology, Soil Fungi, and Fungal Ecology.

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