What is the Difference Between Benfotiamine and Thiamine

Thekey differencebetween benfotiamine and thiamineis that Benfotiamine has a faster absorption rate in the body than thiamine.

Benfotiamine是一种化学物质，在化学上与硫胺素相似。当我们将Benfotiamine从嘴里带走时，它会转化为我们体内的硫胺素。

内容

1.Overview and Key Difference
2.什么是benfotiamine
3.What is Thiamine
4.Benfotiamine vs thiamine以表格形式
5.概括

什么是benfotiamine?

Benfotiamine is a chemical substance that is similar to thiamine, but our body can absorb it better than thiamine. When we take Benfotiamine through the mouth, it converts into thiamine inside our bodies. Usually, this substance is produced from certain plants, e.g. garlic and onion. It can also be produced inside a laboratory through a chemical reaction. Benfotiamine is useful as a medicine for nerve damage that is caused by diabetes and alcoholism. Also, we can use this substance as a medication forAlzheimer disease, arthritis, etc.

硫山is an essentialmicronutrientfor our body. However, some people do not have thiamine in sufficient amounts in our body. Since our body can absorb Benfotiamine faster than thiamine, we can use Benfotiamine as a medication to treat thiamine deficiency.

When considering the side effects of Benfotiamine, they are very rare, but some people have reported stomach problems and skin rashes.

什么是硫胺素？

硫山e is a vitamin compound that we can find in food, medicine, and dietary supplements. It is also known asthiamin或者vitamin B1. The major sources of food containing thiamine include whole grains, legumes, some meat types and fish. Moreover, the grain process can remove most of the thiamine from grains; thus, most of the cereals and flour are enriched with thiamine. Lack of thiamine can cause thiamine deficiency. The disorders that can result in thiamine deficiency include beriberi andWernicke脑病.

The routes of administration for thiamine include oral administration, IV and IM. The drug class of this medication is “vitamin”, and the elimination half-life of it is 1.8 days. The chemical formula for thiamine is C12H17N4OS+. The molar mass of this substance is 265.35 g/mol. This is an essential micronutrient that our body cannot produce itself. However, we need this vitamin for metabolism functions, including glucose, amino acid, and lipid metabolism. Therefore, we need to get it either from food or from dietary supplements.

Typically, thiamine is non-toxic and well-tolerated upon oral administration. However, there can be side effects of it that rarely occurs upon theIV administration, which include allergic reactions, nausea, lethargy, and impaired coordination.

When considering the chemical properties of thiamine, it is a colourless organosulfur compound having an unpleasant sulfur odour, and its chemical structure contains an aminopyrimidine and a thiazonium ring that are linked with each other through a methylene bridge. This substance is water-soluble and also soluble in water, methanol, and glycerol. Practically, it is less soluble in less polar solvents. Furthermore, it has basic properties, which makes it able to react with acids forming salts.

Benfotiamine和Thiamine有什么区别？

Benfotiamine是一种化学物质，在化学上与硫胺素相似。当我们将Benfotiamine从嘴里带走时，它会转化为我们体内的硫胺素。Benfotiamine和Thiamine之间的主要区别在于，我们体内对Benfotiamine的吸收比硫胺素更好。

下表总结了Benfotiamine和Thiamine作为并排比较之间的差异。

摘要 - Benfotiamine vs Thiamine

Benfotiamine是一种化学物质，在化学上与硫胺素相似。当我们将Benfotiamine穿过嘴巴时，它会转化为我们体内的硫胺素。Benfotiamine和Thiamine之间的主要区别在于，我们体内对Benfotiamine的吸收比硫胺素更好。因此，班佛胺对于治疗硫胺素缺乏很重要。

Reference:

1.“”BENFOTIAMINE: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews.”WebMD.

Image Courtesy:

1.“”Benfotiamine Ball and-Stick” By MarinaVladivostok – Own work (CC0) via Commons Wikimedia
2. “硫山“By NEUROtiker – Own work (Public Domain) via Commons Wikimedia