Thekey differencebetween theophylline and aminophylline is thattheophylline is more potent and longer-acting than aminophylline.
Both theophylline and aminophylline are important as drugs in medical applications. Theophylline is used as a drug for the treatment of diseases in the respiratory tract. Aminophylline is also common as a treatment for airway obstruction fromasthma.
内容
1.Overview and Key Difference
2.What is Theophylline
3.What is Aminophylline
4.Side by Side Comparison – Theophylline vs Aminophylline in Tabular Form
5.概括
什么是茶碱?
Theophylline is a drug we use in treating respiratory diseases such asCOPD(chronic obstructive pulmonary disease) and asthma. It is a methylxanthine drug that has the chemical name 1,3-dimethylxanthine since it has two methyl groups attached to a xanthine molecule. Due to this reason, this drug falls under the category of xanthine family; thus, the structure is similar to caffeine and theobromine. Moreover, this compound is found in nature as a component of tea and cocoa.
The chemical formula of the compound is C7H8N4O2while the molar mass is 180.16 g/mol. When considering the medical uses of this compound, it is important in relaxing the bronchial smooth muscle, in increasing the heart rate, in anti-inflammatory effects, in increasing renal blood flow, etc. However, it can be toxic if we don’t monitor the theophylline level in serum. The adverse effects include nausea, diarrhoea, increased heart rate, abnormal heart rhythms, etc.
氨茶碱是什么?
Aminophylline is a drug we use to treat asthma or COPD but has low effectiveness than theophylline. The compound has bronchodilator theophylline and ethylenediamine in the ratio 2:1. Usually, we can find this compound in the dehydrated form, and ethylenediamine improves the solubility of this compound. Although both theophylline and aminophylline are important as drugs for the treatment of COPD, aminophylline is less potent and shorter-acting in this role.
The chemical formula of the compound is C16H24N10O4while the molar mass is 420.42 g/mol. When considering the medical uses, it is important in treating airway obstruction by asthma, emphysema and chronic bronchitis. Moreover, it is useful to reverse regadenoson, dipyridamole, preventing slow heart rates, etc. However, this compound can lead to theophylline toxicity.
What is the Difference Between Theophylline and Aminophylline?
茶碱是一种我们用来治疗呼吸道疾病(例如COPD和哮喘)的药物。相比之下,氨基氨基氨酸是一种我们用来治疗哮喘或COPD的药物,但其有效性低于茶碱。因此,茶碱和氨基苯胺之间的关键区别在于,茶碱比氨基苯胺更有效,更长。
Moreover, the chemical formula of theophylline is C7H8N4O2,摩尔质量为180.16 g/mol。但是对于氨基氨基氨酸,化学式为c16H24N10O4,and the molar mass is 420.42 g/mol. When considering the solubility in water, theophylline is less water-soluble compared to aminophylline. Another difference between theophylline and aminophylline is that the elimination half-life of theophylline is less than that of aminophylline.
总结-茶碱vs Aminophylline
Theophylline is a drug we use in treating respiratory diseases such as COPD and asthma, while aminophylline is a drug we use in treating asthma or COPD, but it has low effectiveness than theophylline. Hence, the key difference between theophylline and aminophylline is that theophylline is more potent and longer-acting than aminophylline.
Image Courtesy:
1. “Cylmin 100mg by Tsuruhara” By Uploader; Vantey – Photographed by Vantey (Public Domain) viaCommons Wikimedia
2. “Aminophylline” By Benrr101 – 100% My own work (Public Domain) viaCommons Wikimedia
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