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器官特异性和组织特异性表现之间的差异

2021年4月15日Posted byDr.Samanthi

Thekey difference在器官特异性和组织特异性表现之间是in organ specific manifestation, the microbes affect the entire organ, while in tissue specific manifestation, the microbes affect the entire tissue.

我们体内有很多组织。组织集体形成器官,即一个个体的生理系统。这些器官共同组成器官系统,并执行身体的特定功能。器官特异性和组织特异性表现是疾病表现的类型。任何疾病的表现都会根据微生物靶向的组织或器官而变化。因此,微生物可以在身体内部传播并移至不同的位置,例如器官或组织。但是,这些微生物没有到达相同的器官或组织。微生物的进入点构成了上述选择的基础。例如,如果条目通过鼻子,微生物可能会进入肺部。如果条目通过嘴,微生物可能会进入肠道。

内容

1.Overview and Key Difference
2.What are Organ Specific Manifestations
3.What are Tissue Specific Manifestations
4.Similarities Between Organ Specific and Tissue Specific Manifestations
5.Side by Side Comparison – Organ Specific vs Tissue Specific Manifestations in Tabular Form
6。概括

什么是器官特定的表现?

Organ specific manifestations are a type of diseases in which a pathogen infects a specific organ. The microbes that enter the body travel to specific organs and multiply in there. Different microbes multiply in different parts of the body. For example,Mycobacterium tuberculosisusually enters the body through our nose and migrates to the lungs. It causes tuberculosis. A person suffering from tuberculosis has several symptoms such as cough, fever, breathlessness and blood sputum, etc., due to the multiplication ofMycobacteriumin the lungs.Salmonellaenters via the mouth (through consumption of contaminated food or water) and travels to the gut lining. Most people withSalmonellainfection have diarrhoea, fever, and stomach cramps.

器官特异性和组织特异性表现之间的差异

Figure 01: Organ Specific Manifestation

Similarly, the virus causing Japanese encephalitis (brain fever) will enter through a mosquito bite and infects the brain. Furthermore, the malarial parasite enters the liver and spreads to red blood cells. Therefore, different microbes have different targets in the body.COVID-19virus is another good example of organ-specific manifestation. The SARS-CoV-2 virus primarily affects the lower respiratory tract while it enters the body through air droplets. Lung involvement is the most serious manifestation, ranging from mild pneumonia to hypoxia. Critical diseases are associated with shock, respiratory failure, and multiorgan failure. If the target organ is known, a slight disturbance in the normal function of that area indicates the onset of a particular disease.

什么是组织特定的表现?

Tissue-specific manifestations refer to a type of disease in which the pathogen infects a specific tissue of an individual. The entire tissue is affected by the microbes. Microorganisms go into tissues and harm them. The resistant immune system enlists disease-causing microorganisms and destroys them. The immune system sends many cells to the affected tissue. We call this process inflammation. We can also observe local effects such as swelling, pain or fever. When the body no longer attempts to fight off, serious complications may arise. The severity of the disease depends on the number of microorganisms.

Key Difference - Organ Specific vs Tissue Specific Manifestations

Figure 02: Tissue Specific Manifestation

当微生物在特定疾病中影响特定细胞或组织类型时,它会提供组织解释的指示。例如,由于某些合成剂(例如组胺和5'Hydroxyptamine trom the受害组织)的细分而发生刺激。这些合成学吸引了血液,导致血液和温度的量度升高。受影响领土的生长被称为刺激。

器官特异性表现和组织特异性表现之间有什么相似之处?

  • They are types of disease manifestations.
  • 微生物涉及这两种途径。
  • 在两种途径中都出现了特定症状。
  • Both pathways damage the human body.

What is the Difference Between Organ Specific and Tissue Specific Manifestations?

当微生物影响整个器官(例如肺,肾脏和大脑)时,它被称为器官特异性表现。当整个组织受微生物的影响时,它被称为组织特异性表现。因此,这是器官特异性和组织特异性表现之间的关键区别。此外,在器官特定的表现中,可以观察到器官特异性症状,例如呼吸困难,黄疸和头痛等,而在组织特异性表现中,可以观察到组织特异性症状,例如肿胀,疼痛,刺激和发烧等。Mycobacterium tuberculosiscausing tuberculosis andSalmonella causing伤寒是器官特定表现的两个例子。艾滋病毒引起艾滋病严重破坏免疫系统是组织特异性表现的一个例子。

The below infographic shows the differences between organ specific and tissue specific manifestations in tabular form.

器官特异性和组织特异性表现之间的差异in Tabular Form

概括– Organ Specific vs Tissue Specific Manifestations

特定器官和组织pecific manifestations depend on the target organ or tissue which the microbes target after entry. Organ specific manifestations refer to the diseases in which the microbes affect the entire organ while tissue specific manifestations refer to the diseases in which the microbes affect the entire tissue. Thus, this is the key difference between organ specific and tissue specific manifestations.

Reference:

1.“Explore Organ Specific And Tissue Specific Manifestations.” BYJU’S, 10 Aug. 2020,Available here.
2. “What Are Organ Specific and Tissues Specific Manifestations?” Doubtnut,Available here.

Image Courtesy:

1.“4844592”(CC0)通过Pixabay
2. “Immune response” By Nason vassiliev – Own work(CC BY-SA 4.0)viaCommons Wikimedia

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Filed Under:疾病

关于the Author:Dr.Samanthi

Samanthi Udayangani博士拥有B.Sc.植物科学学位,硕士在分子和应用微生物学和应用微生物学中的博士学位。她的研究兴趣包括生物肥料,植物 - 微生物相互作用,分子微生物学,土壤真菌和真菌生态学。

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