狼疮与类风湿关节炎
Both rheumatoid arthritis and lupus arthritis affect the peripheral joints. Both present with pain, swelling, and stiffness, and both arthritis have systemic manifestations. Though they present with similar symptoms, clinically rheumatoid arthritis and lupus are different. This article will discuss both rheumatoid arthritis and lupus and the differences between them in detail, highlighting their clinical features, symptoms, investigation and diagnosis, prognosis, and also the course of treatment/management they require.
Rheumatoid Arthritis
类风湿关节炎是一种持久的变形关节炎。It usually affects both sides at once. (Ex: rheumatoid arthritis of both wrist joints). Normally it involves joints at body extremities. (Ex: fingers, toes, ankle and wrist). Rheumatoid arthritis occurs most commonly in the fifth decade. It affects females more than males. Smokers are at a higher risk of getting rheumatoid arthritis. It usually presents with swollen, painful, stiff hands and feet.Rheumatoid symptoms早上更糟。有时，类风湿关节炎也会影响较大的关节。除了这种典型的演讲外，还有一些非典型演示。
类风湿关节炎很少作为各种关节的复发性多重关节炎，持续性的单性关节炎，全身性疾病，关节疾病最少，含糊的肢体腰带疼痛和突然发作性关节炎。既定类风湿关节炎有三个特征性关节畸形。它们是Boutonniere的畸形，天鹅颈部畸形和Z拇指畸形。超弯曲的近端 - 近端接头与超延伸远端远端 - 指称的组合称为Boutonniere的畸形。这可以在2中发生ndto 5Th手指。超延伸近端 - 沿司司烷基与超柔性远端远端接头的组合称为称为swan neck deformity。超级弯曲的卷 - 甲状腺关节，超弯曲的掌骨 - 指关节与拇指的超延伸范围内关节的组合称为Z拇指。Apart from joint features there can be lowhemoglobin，，，，small nodules under the skin,lymph node扩大，腕管综合征，低white blood cell数数，减肥，红眼睛疼痛，眼睛干，呼吸困难，胸痛，骨头弱以及类风湿关节炎的频繁骨折。
关节的X射线显示关节和骨侵蚀的松动。定期运动对于热身关节和减轻疼痛至关重要。关节夹在受影响的关节上取消应变。类固醇注射减少关节炎症。NSAID也减少关节炎症。疾病修饰诸如磺胺吡啶，甲氨蝶呤和环孢素蛋白等药物的疾病会干扰疾病机制，并减慢疾病的进展。
狼疮Arthritis
系统性红斑狼疮是一种多系统疾病。易感人士形成抗体against self-molecules. Therefore, tissues all over the body show signs of炎。全身性红斑狼疮的关节炎是非弱势性的。关节炎不会破坏关节软骨和骨骼的关节表面。通常，该疾病涉及两个或多个关节。他们嫩，痛苦和僵硬。流体可以在关节空间中积聚，从而导致积液。90％的全身性红斑狼疮患者表现出关节受累。关节囊可以松开（共临床）。这会变形关节。这就是所谓的Jaccoud的关节炎。涉及关节附近的骨头的一部分可能死亡（无菌坏死）。
狼疮和类风湿关节炎有什么区别？
•狼疮性关节炎（LA）很少见，但是类风湿关节炎（RA）很常见。
• Lupus arthritis does not destroy joints while rheumatoid arthritis does.
•狼疮关节炎可能是单侧的，而类风湿关节炎是双侧的。
•晚上的类风湿关节炎症状恶化，而狼疮性关节炎症状全天更加弥漫。
•所有全身性红斑狼疮患者均未患有关节炎，但所有类风湿关节炎患者均均涉及共同参与。
•狼疮性关节炎患者测试抗核抗体阳性，而类风湿关节炎患者没有测试。
•所有类风湿关节炎的患者均为类风湿因子阳性，而只有40％的全身性红斑狼疮为类风湿因子阳性。
You may also be interested in reading:
3. d骨关节炎和类风湿关节炎之间的杂质
Hi have been tested for Lupus but dr can’t decide whether it is lupus or RA – have been taken meds for Lupus – hydrocholo… – also positive for TB – pain in joints get worse during the day and night – fingers swollen – would like o know what is what – is it lupus or RA – can’t seem to get answer from dr.
将appreciate your import
Lillian acosta