IBS和Crohn的区别

关键区别 - IBS vs Crohn's

IBS和Crohn病是两种影响胃肠道的疾病。肠易激综合症or IBS is defined as a functional derangement of theintestinesthat gives rise to altered bowel habits and abdominal pain whereas Crohn’s disease is an inflammatory bowel disease characterized by the transmuralinflammation结肠粘膜。虽然冒号is inflamed in the Crohn’s disease, no such inflammatory processes are observed in IBS.这可以被认为是IBS和Crohn's之间的关键区别。

CONTENTS

1。概述和关键差异
2。什么是IBS
3。克罗恩是什么
4。Similarities Between IBS and Crohn’s
5。Side by Side Comparison – IBS vs Crohn’s in Tabular Form
6。Summary

什么是IBS？

肠易激综合症或IBS定义为肠道的功能危险，导致肠习惯和腹痛改变。标志性的特征是结肠结构中没有任何炎症过程。

临床表现

• 肠习惯的改变 - 这可以是便秘或diarrhea
• Abdominal pain
• Clear or white mucorrhea
• 性功能障碍
• 消化不良
• Nausea, vomiting
• 尿频和紧迫性
• 纤维肌痛
• 症状恶化在外膜期间

诊断

IBS的诊断基于以下标准。

患者应在3个月内至少有两个临床特征的腹痛至少3个月。

• 疼痛应与排便有关
• 变化频率
• 改变粪便的质地

存在其他症状，例如粘毛和腹腔肿块的诊断。

There are main four varieties of IBS

• 肠易激综合症-D: diarrhea is more prominent
• IBS-C：便秘是突出的
• IBS-M：混合腹泻和便秘
• IBS-U：临床演示与以上三类不相似
  

  图01：胃肠系统

Management

非药理管理包括

• 改变饮食习惯比如增加纤维content of the diet and decreasing the amount of psyllium compounds to minimize the flatulence
• Drinking more water
• 减少豆类消耗可以防止腹胀

Pharmacological Intervention

• 抗胆碱能力，例如二环球
• Antidiarrheals such as loperamide
• 三环抗抑郁药
• 原始学
• Bulk-forming laxatives

克罗恩是什么?

克罗恩病是一种炎症性肠病，其特征是结肠粘膜的透壁炎症。Usually, only some regions of the colon are inflamed giving rise to skip病变而不是连续参与。

临床表现

Diarrhea

克罗恩病的腹泻是由于流体的分泌过多以及发炎的肠粘膜吸收流体受损。除此之外，发炎的末端回肠对胆汁盐的吸收不良也有助于加剧腹泻。

Fibrostenotic Disease

The obstruction of the gastrointestinal tract due to small bowel strictures or colonic strictures can rise to symptoms such as abdominal pain, constipation, nausea, and vomiting.

瘘管疾病

GIT的透壁炎症可能是窦道，浆膜渗透和瘘管的原因，例如肠肠瘘。炎症病变肠道的渗透导致结肠物质渗入腹膜腔，导致腹膜炎和其他相关并发症。

Local Complications of Crohn’s Disease

• 由于对结肠水和电解质吸收的刺激作用而引起的水状腹泻
• The reduced concentration of bile acids interrupts the absorption of fat, resulting in steatorrhea
• Long-term steatorrhea can lead toosteoporosis，，，，malnutrition和凝结异常
• 形成gallstones
• Nephrolithiasis (formation ofkidney stones）
• Vitamin B12malabsorption

克罗恩病增加了冒号cancers，，，，淋巴瘤andsquamous cell carcinomasof the anus.

形态学

宏观检查

Mostly the right side of the colon is affected by the Crohn’s disease. There is a segmental distribution of the lesions. Usually, the rectum is spared.

显微镜

裂隙和非造成肉芽肿的发生存在透壁参与。

诊断

临床病史和检查在CD的诊断中起着至关重要的作用。

内窥镜检查揭示了存在散溃疡的存在，这些溃疡会导致鹅卵石外观。腹部和骨盆扫描可用于识别任何脓肿。

Management

克罗恩氏病无法治愈。治疗的目的是抑制炎症过程，从而导致临床表现的体征和症状。

抗炎药

Corticosteroids such as泼尼松龙

Aminosalicylates

• 免疫系统抑制剂，例如硫唑嘌呤和生物剂，例如英夫利昔单抗
• Antibiotics
• Analgesics
• Antidiarrheals
• 铁和维生素B12补充剂

In some cases, surgical removal of the damaged parts of the colon is required.

What are the Similarities Between IBS and Crohn’s?

• 两者都是胃肠道的疾病。
• Diarrhea is a common symptom seen in both conditions.

What is the Difference Between IBS and Crohn’s?

IBS vs Crohn的
肠易激综合征定义为肠道的功能危险，导致肠习惯改变和腹痛改变。	克罗恩病是一种炎症性肠病，其特征是结肠粘膜的透壁炎症。
结肠粘膜
There is no inflammation of the colonic mucosa.	Colonic mucosa is inflamed.
Constipation
有时将便秘视为症状。	Constipation is not a symptom.

Summary – IBS vs Crohn’s

克罗恩病是一种炎症性肠病，其特征是结肠粘膜的透壁炎症。肠道的功能危险导致肠习惯改变和腹痛被确定为肠易激综合征。仅在克罗恩氏病，而在IBS中观察到炎症。

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参考：

1。Kumar, Vinay, Stanley Leonard Robbins, Ramzi S. Cotran, Abul K. Abbas, and Nelson Fausto. Robbins and Cotran pathologic basis of disease. 9th ed. Philadelphia, Pa: Elsevier Saunders, 2010. Print.

图片提供：

1。“Crohn’s Disease” By BruceBlaus – Own work(CC BY-SA 4.0）通过下议院维基梅迪亚
2。“Blausen 0432 GastroIntestinalSystem” By Blausen.com staff (2014). “Medical gallery of Blausen Medical 2014”. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. – Own work（CC由3.0）通过下议院维基梅迪亚