抗体are composed ofB cells并且是参加免疫反应的免疫球蛋白。抗体可以根据其结构，功能，其反应类型和辅助成分的存在而具有不同的类别。响应于antigen和thus, also termed as antigenic determinants. Once the antibody recognizes an antigen, it binds to the antigen specifically to form an antigen-antibody complex. The complex formation will eventually activate defense mechanisms or directly degrade the foreign body that enters the system.凝集是作为宿主防御机制发生的一种抗体 - 抗原反应。在此反应过程中，抗体与抗原结合并形成一种络合物，最终结合在一起。基于凝集的特性，可以将抗体分为两种主要类型。完整的抗体和不完整的抗体。
完整的抗体是一种B细胞免疫球蛋白，与抗原结合后参与凝集反应。完整的抗体具有与抗原结合并形成团块或凝集素的特定特性，使得能够宿主吞噬细胞to identify the large foreign particle.免疫球蛋白G是一种完整抗体的常见类型。这将导致宿主防御机制的激活。这将吞没整个综合大楼。完整抗体的两个主要应用是血凝和白血谷物。产生的抗体红细胞和白血细胞are complete antibodies and hence participate in agglutination reactions. Therefore, these agglutination tests are done during blood transfusion procedures to check the compatibility of blood groups between the donor and the recipient. If the agglutination occurs, the blood groups are incompatible and vice versa. Complete antibodies are also produced against many bacterial infections, and these complete antibodies form agglutinations with bacterial pathogens and initiate phagocytic reactions.
凝集reactions are therefore used widely as diagnostic tests to identify the presence of a bacterial pathogen. Synthetic complete antibodies are tested体外for the suspect’s blood sample, and the presence of agglutins confer the occurrence of the particular infection. This test is of high precision and reliability.
In this test, the incomplete antibodies are allowed to bind to synthetic, specific target molecules known as antiglobulins. This is analyzed in order to determine the presence or the absence of the particular antibody in the serum. By doing this test procedure, a specific condition can be diagnosed and conformed. The incomplete antibodies are involved in indirectly activating an immune defense mechanism other than agglutination.
What are the Similarities Between Complete and Incomplete Antibodies?
- Both are composed of B cells.
- Both show high specificity.
- Both are involved in recognizing an antigen of a foreign cell.
- 如血清或血液样本be used for diagnostic tests of these antibodies.
|Complete antibodies form complexes with antigens which results in clumps or agglutinations.||Complex formation with an antigen does not occur in incomplete antibodies. Hence, they stay as free antibodies in response to an antigen.|
|凝集reactions are detecting as a test reaction for the identification of complete antibodies.||Coombs’ test – serum analysis of incomplete antibodies using antiglobulins is done for incomplete antibodies.|
抗体play a pivotal role in a host defense mechanism and participate in protecting the host from external attack by infectious agents or foreign substances. Identification of these foreign bodies is important to avoid any clinical manifestations arising from these agents. Complete and incomplete antibodies are types of antibodies which differ in their ability and inability to participate in agglutination reactions. Due to this contrast mechanisms of complete and incomplete antibodies, the diagnostic test procedures based on these antibodies are also differed significantly. This is the difference between complete and incomplete antibody.
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1.“Agglutination (Biology).” Wikipedia, Wikimedia Foundation, 9 Sept. 2017. Accessed 2 Oct. 2017.Available here
2.“Coombs test.” Wikipedia, Wikimedia Foundation, 13 Aug. 2017, Accessed 2 Oct. 2017.Available here