区别Between Complete and Incomplete Antibodies

Key区别–Complete与不完全的抗体

抗体are composed ofB cells并且是参加免疫反应的免疫球蛋白。抗体可以根据其结构，功能，其反应类型和辅助成分的存在而具有不同的类别。响应于antigen和thus, also termed as antigenic determinants. Once the antibody recognizes an antigen, it binds to the antigen specifically to form an antigen-antibody complex. The complex formation will eventually activate defense mechanisms or directly degrade the foreign body that enters the system.凝集是作为宿主防御机制发生的一种抗体 - 抗原反应。在此反应过程中，抗体与抗原结合并形成一种络合物，最终结合在一起。基于凝集的特性，可以将抗体分为两种主要类型。完整的抗体和不完整的抗体。

即使完整的抗体在识别抗原后具有抗原凝集的能力，但不完全的抗体也没有凝集的能力。相反，它只参与识别和识别抗原。Thekey difference在完整和不完整的抗体之间是凝集的能力或无能。

内容

1.Overview and Key Difference
2.什么是完整的抗体
3.什么是不完整的抗体
4.完整抗体和不完整的抗体之间的相似之处
5。并排比较 - 完整与表格形式不完整的抗体
6。概括

什么是完整的抗体?

完整的抗体是一种B细胞免疫球蛋白，与抗原结合后参与凝集反应。完整的抗体具有与抗原结合并形成团块或凝集素的特定特性，使得能够宿主吞噬细胞to identify the large foreign particle.免疫球蛋白G是一种完整抗体的常见类型。这将导致宿主防御机制的激活。这将吞没整个综合大楼。完整抗体的两个主要应用是血凝和白血谷物。产生的抗体红细胞和白血细胞are complete antibodies and hence participate in agglutination reactions. Therefore, these agglutination tests are done during blood transfusion procedures to check the compatibility of blood groups between the donor and the recipient. If the agglutination occurs, the blood groups are incompatible and vice versa. Complete antibodies are also produced against many bacterial infections, and these complete antibodies form agglutinations with bacterial pathogens and initiate phagocytic reactions.

凝集reactions are therefore used widely as diagnostic tests to identify the presence of a bacterial pathogen. Synthetic complete antibodies are tested体外for the suspect’s blood sample, and the presence of agglutins confer the occurrence of the particular infection. This test is of high precision and reliability.

什么是不完整的抗体？

不完整的抗体主要是免疫球蛋白m，并且它们与抗原结合后不参与凝集反应。取而代之的是，这些抗体是根据特定抗原产生的。通过使用抗球蛋白，可以在血清中检测到不完全的抗体作为游离抗体。该测试称为Coombs’ test.

In this test, the incomplete antibodies are allowed to bind to synthetic, specific target molecules known as antiglobulins. This is analyzed in order to determine the presence or the absence of the particular antibody in the serum. By doing this test procedure, a specific condition can be diagnosed and conformed. The incomplete antibodies are involved in indirectly activating an immune defense mechanism other than agglutination.

What are the Similarities Between Complete and Incomplete Antibodies?

• Both are composed of B cells.
• Both show high specificity.
• Both are involved in recognizing an antigen of a foreign cell.
• 两者都在体外诊断测试程序，特别是确定感染的开始。
• 如血清或血液样本be used for diagnostic tests of these antibodies.

完整抗体和不完整的抗体有什么区别？

完整的抗体与不完整抗体
完整的抗体具有识别抗原后用抗原形成凝集的能力。	不完整的抗体不会产生，它是对抗原的唯一反应。
Mechanism
Complete antibodies form complexes with antigens which results in clumps or agglutinations.	Complex formation with an antigen does not occur in incomplete antibodies. Hence, they stay as free antibodies in response to an antigen.
测试反应类型
凝集reactions are detecting as a test reaction for the identification of complete antibodies.	Coombs’ test – serum analysis of incomplete antibodies using antiglobulins is done for incomplete antibodies.
Examples
免疫球蛋白G和血型抗体是完整抗体的例子。	免疫球蛋白M是不完全抗体的一个例子。

概括– Complete与不完全的抗体

抗体play a pivotal role in a host defense mechanism and participate in protecting the host from external attack by infectious agents or foreign substances. Identification of these foreign bodies is important to avoid any clinical manifestations arising from these agents. Complete and incomplete antibodies are types of antibodies which differ in their ability and inability to participate in agglutination reactions. Due to this contrast mechanisms of complete and incomplete antibodies, the diagnostic test procedures based on these antibodies are also differed significantly. This is the difference between complete and incomplete antibody.

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Reference:

1.“Agglutination (Biology).” Wikipedia, Wikimedia Foundation, 9 Sept. 2017. Accessed 2 Oct. 2017.Available here
2.“Coombs test.” Wikipedia, Wikimedia Foundation, 13 Aug. 2017, Accessed 2 Oct. 2017.Available here

Image Courtesy:

1.’Coombs test schematic’By A. Rad~commonswiki assumed. Own work assumed (based on copyright claims).（CC BY-SA 3.0）viaCommons Wikimedia