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绝对和相对难治期之间的差异

2018年2月11日Posted bySamanthi博士

Key Difference – Absolute与相对难治​​期

Action potential一个nerveimpulse refers to the phenomenon in which a nerve impulse is transmitted across a神经元。这是浓度差异的结果钠(Na+) ions和钾(K+) ions across the membrane. There are three main phases of action potential;去极化,复极化和超极化。不应期是the period that immediately follows a nerve impulse transmission or an action potential. This is also regarded as the characteristic recovery time of one action potential before the second. There are two main types of refractory periods in physiology; the absolute refractory period and the relative refractory period. The absolute refractory period refers to the time span in which the Sodium channels remain inactive. The relative refractory period is the phenomenon in which the Sodium gated channels transit from its inactive state to the closed status that prepares the channels to be activated. Then the membrane gains the ability to initiate the second signal for nerve transmission. The关键区别绝对和相对耐火周期之间是基于钠离子门控通道。The absolute refractory period is the period in which the sodium-gated ion channels are completely inactive whereas the relative refractory period is the time span where the inactive sodium channels transit to the active form to accept the second signal.

CONTENTS

1。概述和关键差异
2。什么是绝对耐火周期
3。What is Relative Refractory Period
4。绝对和相对难治期之间的相似性
5.并排比较 - 表格形式的绝对与相对难治​​期
6.Summary

什么是绝对耐磨时间?

绝对折射期是指钠离子通道完全不活跃的时期。钠离子通道打开后,这是非常快速和自发的。当钠离子通道失活时,它们无法立即回到活动状态。因此,激活钠离子通道所需的初始恢复时间被描述为绝对耐火周期。该过程是一个依赖电压的过程。绝对耐受期可以持续1-2毫秒,而总回收周期约为3-4毫秒。

During the absolute refractory period, a second action potential is not initiated because the sodium ion channels are fully inactivated. Therefore, any additional depolarization stimuli do not take place during this period. The neurons are not excited during this period. Thus, the neuron excitability is null during the Absolute refractory period.

绝对和相对难治期之间的差异

图01:耐火周期

就神经冲动传播过程中动作电位的频率而言,绝对耐火周期决定了沿该动作电位的最大频率plasma membraneof the轴突。Therefore, this is responsible for setting the upper limit of the action potential at any given time. This phenomenon has a physiological significance. The absolute refractory period can be used to predict the manner in which the nervous system responds to different high-frequency stimuli and to determine its effects on different effector organs or muscles.

What is Relative Refractory Period?

Upon the completion of the absolute refractory period, the sodium ion channels begin to activate, which is the final phase of the recovery period. A much stronger signal is required by the sodium ion channels to recover back to the active form from its complete inactive state.

接收更强信号以激活钠离子通道的时期称为相对难治期。这构成了完整耐火周期的后期。在相对难治期间,钾的离子通透性保持在静息膜电位值之上。这将导致钾离子从细胞流出。这将激活该过程,第二个信号将输入。

绝对和相对难治期之间有什么相似之处?

  • 绝对耐火周期和相对耐火周期都是在神经冲动传播过程中发生的难治时期的组成部分。
  • Both absolute refractory period and the relative refractory period are dependent on the sodium and potassium ion channels.

绝对和相对难治期有什么区别?

绝对与相对难治​​期

The absolute refractory period refers to the time span in which the Sodium channels remain inactive. 相对耐火周期是钠门控通道从其无活性状态到封闭状态的现象,该状态准备要激活的通道。
Stimulus
During the absolute refractory period, the stimulus will not produce a second action potential. During the relative refractory period, the stimulus must be stronger than the usual to produce the action potential.
离子通道参与
The sodium ion channels are completely inactive during the absolute refractory period. 钾离子通道是活跃的,并且在相对难治期间从细胞中流出钾。

Summary – Absolute与相对难治​​期

神经冲动传播期间的难治时期的特征是绝对耐受期和相对难治时期。在绝对难治期间,NA+渠道是完全不活动的,因此无法发起任何动作潜力。在相对难治期,NA+channels undergo a recovery period in which they transit to the active state. A much stronger second stimulus is required for this process. This is the difference between absolute and relative refractory period.

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参考:

1.“ 2014年神经传播。”难治期。在这里可用
2.“绝对难治时期:定义和意义。”stuce.com。在这里可用
3。Team, PhysiologyWeb. Refractory Periods – Neuronal Action Potential – PhysiologyWeb.在这里可用

图片提供:

1。’Action potential’ By Chris 73, updated Diberri, converted to SVG by tiZom – Own work,(CC BY-SA 3.0)通过下议院维基梅迪亚

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关于作者:Samanthi博士

Samanthi博士Udayangani holds a B.Sc. Degree in Plant Science, M.Sc. in Molecular and Applied Microbiology, and PhD in Applied Microbiology. Her research interests include Bio-fertilizers, Plant-Microbe Interactions, Molecular Microbiology, Soil Fungi, and Fungal Ecology.

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