Thekey differencebetween primary and secondary Sjogren’s syndrome是在没有另一个基础的情况下,主要的Sjogren综合征发生autoimmune disease, while secondary Sjogren’s syndrome is associated with another autoimmune disease.
Sjogren’s syndrome (SS) is an autoimmune disease that affects the moisture of the body through the lacrimal and salivary glands and has a long-term effect. SS is usually associated with autoimmune disorders such asrheumatoid arthritis,全身性红斑狼疮或系统性硬化症. There are two types of SS known as primary and secondary. Primary SS occurs independent of other health problems or disorders, and secondary SS occurs as a result of other connective tissue disorders or health problems.
内容
1.Overview and Key Difference
2.是什么Primary Sjogren’s Syndrome
3.是什么Secondary Sjogren’s Syndrome
4.相似之处 - 初级和中学综合症
5。主要与次级Sjogren的综合征以表格形式
6。Summary – Primary and Secondary Sjogren’s Syndrome
什么是主要的Sjogren综合征?
Primary Sjogren’s syndrome is an autoimmune disease where lymphatic infiltration of lacrimal and salivary glands occurs, causing dry eyes and dry mouth, respectively. Primary SS usually occurs due to the lymphoid infiltration of the lung, kidney, stomach, liver, skin, and muscles and shows extra glandular features. Initially, during pathogenesis, the lymphocytes that infiltrate salivary glands and lymph nodes with the use of monoclonal antibodies identify distinct lymphocyte subsets.
主要SS并不是由于其他健康问题而引起的。它显示出轻度的全身性迹象,例如疲劳和疼痛,它们通过运动和短期中等剂量的糖皮质激素和疾病改良药物进行治疗。然而,严重和急性的疾病需要用糖皮质激素和免疫抑制药物进行晚期治疗。
是什么Secondary Sjogren’s Syndrome?
Secondary Sjogren’s syndrome is an autoimmune disease that causes extreme dryness in the mouth and eyes and is influenced by another autoimmune disease such as rheumatoid arthritis or lupus. This makes the production of saliva and tears difficult since the moisture-producing glands are damaged. A hallmark of this disease is the infiltration of target organs by lymphocytes. Secondary SS is a mild form of SS, and the most common cause is rheumatoid arthritis.
常见的症状包括干眼,口干,喉咙干燥和干燥的上部气道。品尝和吞咽食物,咳嗽,牙齿问题,嘶哑和说话困难的困难也经历了。没有完全治愈次级SS的方法,因此治疗过程可以减轻症状并改善健康状况。刺激眼泪和唾液分泌的药物也用于治疗。
初级和继发性Sjogren综合征之间有什么相似之处?
- Primary and secondary Sjogren’s Syndrome are autoimmune diseases.
- 两者都表现出干燥的眼睛和干嘴。
- Common symptoms of both conditions are fatigue, fever, and pain in joints, muscles, and nerves.
- 活检,血液检查和Schirmer的测试可用于诊断这两种情况。
- Severe cases of both primary and secondary Sjogren’s syndrome affect vital organs such as kidneys, lungs, liver, blood vessels, stomach, pancreas, and brain.
- Genetics and environmental factors play a role in the onset of both conditions.
主要和次级Sjogren综合征有什么区别?
Primary Sjogren’s syndrome takes place in the absence of another underlying autoimmune disease, while secondary Sjogren’s syndrome is associated with another autoimmune disease. This is the key difference between primary and secondary Sjogren’s syndrome. Primary SS is more severe, and secondary SS is milder and has a slower progression. There is no complete cure for secondary SS, unlike primary SS. Primary SS is treated with glucocorticoids and immunosuppressant drugs.
下表总结了主要和次级Sjogren综合征之间的差异。
摘要 - 初级与次级Sjogren综合征
Sjogren’s syndrome is an autoimmune disease that affects the moisture of the body through the lacrimal and salivary glands and has a long-term effect. There are two types as primary and secondary Sjogren’s syndrome. Primary Sjogren’s syndrome takes place without any other underlying autoimmune disease, while secondary Sjogren’s syndrome takes place in association with another autoimmune disease. Common causes for Sjogren’s syndrome are genetic influence, environmental, and other factors, including autoimmune disorders. This summarizes the difference between primary and secondary Sjogren’s syndrome.
Reference:
1. Pietrangelo,Ann。“次级Sjogren综合征和关节炎.” Healthline, Healthline Media, 15 Aug. 2018.
2. Sisó-Almirall, Antoni, et al. “Primary Sjögren Syndrome in Primary Health Care干燥综合征,2011年,页。501 - 514。
Image Courtesy:
1.“”Sjogrens Syndrome“ 经过Scientific Animations–(CC BY-SA 4.0)通过Commons Wikimedia
2. “Secondary Raynaud’s in Sjögren’s syndrome 1“ 经过Intermedichbo – User:Milorad Dimic MD(CC BY-SA 3.0)通过Commons Wikimedia
发表评论