What is the Difference Between Adapalene and Benzoyl Peroxide

Thekey difference between adapalene and benzoyl peroxideis that adapalene is aretinoid, whereas benzoyl peroxide is anantibioticand skin-peeling agent.

Adapalene and benzoyl peroxide are well-known medications in treatingacneskin. They both show considerable results, but there are some differences between these two chemicals.

CONTENTS

1.Overview and Key Difference
2.What is Adapalene
3.What is Benzoyl Peroxide
4.Adapalene vs Benzoyl Peroxide in Tabular Form
5.Summary – Adapalene vs Benzoyl Peroxide

What is Adapalene?

Adapalene is a type of topical retinoid that is useful in treating mild to moderate acne and can be used as an off-label medicine to treat keratosis pilaris and some other skin conditions. This medicine is considered to be the least effective medicine among other topical retinoids we use to treat acne vulgaris. However, it has some advantages over retinoids as it is more stable and can lead to fewer concerns towards photodegradation. Further, this compound is more chemically stable and usually is used as a first-line agent.

The trade names for adapalene include Differin, Pimpal, Gallet, Adelene, and Adeferin. Its bioavailability is very low, and its excretion occurs through bile. The chemical formula of adapalene is C28H28O3 and its molar mass is 412.52 g/mol.

The most common side effects of adapalene include photosensitivity, irritation, redness, dryness, itching, and burning. These are mild and common side effects that tend to decrease over time. Severe allergic reactions are rare for this medicine.

What is Benzoyl Peroxide?

Benzoyl peroxide is an organic compound having the chemical formula C₁₄H₁₀O₄. There are two major applications of this compound; as medication and as an industrial chemical. The molar mass is 242.33 g/mol. It has a melting point in the range of 103 to 105 °C. However, it tends to undergo decomposition. It is water-insoluble because it cannot form hydrogen bonds with water molecules.

This compound is a major ingredient in medication and cosmetics that we use to treat acne. We use it to treat mild or moderate acne conditions. Other than that, we use this compound as bleaching flour, for hair bleaching purposes, teeth whitening, textile bleaching purposes, etc. There are some side effects of using benzoyl peroxide, such as skin irritation, dryness, peeling, etc.

What is the Difference Between Adapalene and Benzoyl Peroxide?

阿apa烯和苯甲酰过氧化苯甲酰是治疗痤疮皮肤的众所周知的药物。它们都显示出可观的结果，但是这两种化学物质之间存在一些差异。adpalene和过氧化苯甲酰的关键区别在于，阿帕列伦是类维生素，而过氧化苯甲酰是抗生素和皮肤脱氧剂。此外，对痤疮的过氧化苯甲酸苯甲酸苯甲酸苯甲酸苯甲酸苯甲酸苯甲酸苯甲酰；此外，Adapalene仅适用于处方，而在柜台上有过氧化苯甲酰，没有处方。

The following table summarizes the difference between adapalene and benzoyl peroxide.

Summary – Adapalene vs Benzoyl Peroxide

阿apa烯和苯甲酰过氧化苯甲酰是治疗痤疮皮肤的众所周知的药物。它们都显示出可观的结果，但是这两种化学物质之间存在一些差异。adpalene和过氧化苯甲酰的关键区别在于，阿帕列伦是类维生素，而过氧化苯甲酰是抗生素和皮肤脱氧剂。此外，Adapalene只有处方可用，而在柜台上有过氧化苯甲酰，没有处方。

Reference:

1. “Adapalene vs. BENZOYL Peroxide: Side Effects & Dosage for Acne Cream.”MedicineNet, MedicineNet, 14 Dec. 2017.

Image Courtesy:

1. “Adapalene structure” By Vaccinationist – Own work (Public Domain) via Commons Wikimedia
2. “Benzoyl peroxide gel” By Obli at the English-language Wikipedia(CC BY-SA 3.0)via Commons Wikimedia