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Difference Between Retinoid and Retinol

June 18, 2020Posted byMadhu

Thekey differencebetween retinoid and retinol is thatretinoid is a group of different chemical compounds, whereas retinol isvitamin A,这是类维生素类团体的成员。

类视黄素是一组与维生素A结构密切相关的化合物。Therefore, we can indicate retinoids as vitamers of vitamin A. Retinol is a member of the retinoid group.

CONTENTS

1.Overview and Key Difference
2.What is Retinoid
3.What is Retinol
4.Side by Side Comparison – Retinoid vs Retinol in Tabular Form
5.概括

What is Retinoid?

Retinoids are a group of organic compounds that can be recognized as vitamers of vitamin A. This means retinoids are chemically related to the vitamin A molecule. Therefore, there are many applications of retinoids in the field of medicine as regulating agents for epithelial cell growth. In addition, there are many important roles for retinoids in our body, including their role in vision, regulation ofcell proliferation,cell differentiationregulation, growth of bone tissues, immune function, activation of tumour suppression, etc.

We can recognize three generations of retinoids; the first generation includes retinol, tretinoin, while the second generation includes etretinate, and the third generation includes adapalene, bexarotene, etc.

Difference Between Retinoid and Retinol

Figure 01: Different Retinoids

When considering the basic structure of retinoid, it has a cyclic end group, a polyene side chain and a polar end group. A conjugated system is formed from the altering C=C bonds present in the polyene side chain. The alternations in the side chain of retinoid main structure cause the formation of different retinoid molecules.

What is Retinol?

Retinol is another name for vitamin A1. It is a major vitamin we can find in many foods. Moreover, we can use it as a dietary supplement to prevent vitamin A deficiency. The route of administration of this vitamin is via the mouth. The chemical formula of this compound is C20H30O, and the molar mass is 286.45 g/mol. There are many medical uses of this compound as a drug.

Key Difference - Retinoid vs Retinol

Figure 02: The Chemical Structure of Retinol

In addition to the treatment of vitamin A deficiency, we can use this as a drug to prevent further issues in those who have measles. However, there are some side effects of this compound as well; high doses can cause an enlarged liver, dry skin and hypervitaminosis A. During pregnancy, high doses may harm the baby. Nevertheless, this drug has many useful effects in our body; we need it for better eyesight, for the maintenance of the skin, etc.

What is the Difference Between Retinoid and Retinol?

类视黄素是一组与维生素A结构密切相关的化合物。因此,我们可以将类视视视网膜定为维生素A的维生素A。视黄醇是类维生素的成员。因此,类视黄醇和视黄醇之间的关键区别在于类视黄素是一组不同的化合物,而视黄醇是维生素A,它是视视视网膜类动物的成员。

The following table summarizes the difference between retinoid and retinol.

Difference Between Retinoid and Retinol in Tabular Form

概括– Retinoid vs Retinol

类视黄素是一组与维生素A结构密切相关的化合物。因此,我们可以将类视视视网膜定为维生素A的维生素A。视黄醇是类维生素的成员。因此,类视黄醇和视黄醇之间的关键区别在于类视黄素是一组不同的化合物,而视黄醇是维生素A,它是视视视网膜类动物的成员。

Reference:

1. “Retinoid.”Retinoid – an Overview | ScienceDirect Topics,Available here.

Image Courtesy:

1. “Retinoids skeletal formulae” By Vaccinationist – Own work (Public Domain) viaCommons Wikimedia
2. “All-trans-Retinol2” By NEUROtiker (talk) – Own work (Public Domain) viaCommons Wikimedia

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Filed Under:Organic Chemistry

About the Author:Madhu

Madhu毕业于具有文学学士学位(荣誉)学位的生物科学,目前是工业和环境化学硕士学位。她的思维牢固地扎根于化学基本原理和对不断发展的工业化学领域的热情,她非常有兴趣成为那些在化学方面寻求知识的人的真正伴侣。

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