这关键区别在X链接主导和X链接的隐性之间是x链接的主导力是遗传性疾病caused due to a dominant mutant gene located on theX染色体while X linked recessive is a genetic disorder caused due to one or two recessive mutant genes located on the X chromosomes.
X链接主导和X链接的隐性是X链接的遗传遗传的两种类型。遗传是由于位于X染色体上的基因所致。遗传疾病由于位于X染色体中的突变基因而发生。女性有两个X染色体,而男性只有一个X染色体。在男性中,一个突变基因的一个副本足以引起X链接的显性或X链接的隐性疾病。但是在女性中,一个突变基因的一个副本足以引起X连接的显性疾病,而需要两个突变基因的副本来引起X连接的隐性障碍。在一个X染色体中携带一个隐性突变基因的女性是载体。
CONTENTS
1。概述和关键差异
2。什么是x链接的主导
3。What is X Linked Recessive
4。X链接主导和X链接隐性膜片之间的相似之处
5。并排比较 - x链接的主导效果与x链接的隐性形式
6.Summary
什么是X链接主导?
x链接的主导力是disorder caused by a mutation in genes on the X chromosome. Only one copy of the mutant gene is sufficient for the disease to occur in both males and females. Some X linked dominant disorders are lethal in males. Moreover, males show severe symptoms of the X linked dominant disorder than females. However, a father cannot pass X linked inheritance to a son since the son receives only Y chromosome from his father. Therefore, there is no male-to-male transmission of X linked disorders. But affected fathers transmit this condition to their daughters.
X连接的主导疾病的一些例子包括维生素D耐药物,RETT综合征,Alport综合征,色素不可药品,Giuffrè-Tsukahara综合征,Goltz综合征,X连锁的主导型斑岩,脆弱的X综合征和Aicardi综合征。
什么是X链接的隐性?
X linked recessive is a condition caused due to recessive mutant genes located in X chromosomes. In females, two mutant gene copies are needed for the disease occurrence. If one mutant copy is present, the normal copy can compensate for the changed copy. She is only a healthy carrier. But in males, one mutant copy is sufficient to cause the X linked recessive disease since males carry only one X chromosome. Males do not carry another copy to compensate the mutant copy like in females.
与X连接的主要疾病类似,父亲不会将X连接的隐性疾病传递给儿子。X连接的隐性疾病的一些例子包括血友病,Duchenne肌肉营养不良,红绿色色盲,X连接的鱼质病和Becker的肌肉营养不良。
X链接主导和X链接的隐性之间有什么相似之处?
- X链接的显性和X连接的隐性疾病是由于X染色体上基因的突变而发生的。
- 改变基因的一个副本就足以导致these two types of disorders in males.
- X连接的疾病没有从父亲传播到儿子。
What is the Difference Between X Linked Dominant and X Linked Recessive?
X连接的显性是由于X染色体上的显性突变基因引起的遗传条件。相反,X连接的隐性是由于X染色体上的一个或两个突变隐性基因引起的遗传条件。因此,这是X链接主导和X链接隐性膜片之间的关键区别。同样,X链接的主要疾病不如X链接的隐性疾病常见。
此外,在X连接的主导优势中,只有一个副本足以引起男性和女性的疾病。在X链接的隐性中,一份副本足以引起男性疾病,但需要两种副本来引起女性疾病。因此,这是X链接主导效果和X链接隐性的另一个重要差异。
Below infographic tabulates the differences between X linked dominant and X linked recessive for side by side comparison.
摘要 - x链接的主导率与x链接的隐性
Genes located on the X chromosomes are responsible for X linked inheritance of diseases. X linked dominant and X linked recessive are two conditions. In X linked dominant, a dominant gene copy on the X chromosome causes the disease. In X linked recessive, one or two copies of recessive genes on the X chromosomes cause diseases. X linked recessive disorders are more common than X linked dominant. Moreover, X linked recessive condition more frequently affects males, while X linked dominant condition more frequently affects females. Thus, this summarizes the difference between X linked dominant and X linked recessive.
参考:
1.“继承模式。”理解遗传学:纽约,大西洋中部患者和卫生专业人员指南。美国国家医学图书馆,2009年7月8日,在这里可用。
2.“遗传条件可以遗传的不同方式是什么?:Medlineplus遗传学。”美国国家医学图书馆Medlineplus,2020年9月17日,在这里可用。
图片提供:
1.文件:常染色体主导者 - en.svg:domaina,angelito7和sum1衍生作品:sum1 - 基于文件:常染色体主导者 - EN.SVG(CC BY-SA 4.0)通过下议院维基梅迪亚
2. “X-linked recessive (2)” By File:Autosomal recessive – en.svg: Domaina, Kashmiri and SUM1Derivative work: SUM1 – Based off of File:Autosomal recessive – en.svg(CC BY-SA 4.0)通过下议院维基梅迪亚
Leave a Reply