Thekey differencebetween thyroxine and triiodothyronine is that甲状腺素包含四个原子iodineper molecule while triiodothyronine contains three atoms of iodine per molecule.
甲状腺是内分泌腺located in the neck area. This gland is important since it produces threehormones. Two of these hormones are essential for regulating metabolism. These two thyroid hormones are thyroxine and triiodothyronine. Both hormones function together in order to control the rate of energy use in our body. The third thyroid hormone is calcitonin and it is important in maintaining calcium homeostasis.
What is Thyroxine?
What is Triiodothyronine?
Triiodothyronine is one of the two major thyroid hormones released by our thyroid gland. Most triiodothyronine in our blood exists as a bound form with proteins. Some amount remains as an unbound form. When measuring the total triiodothyronine, it gives the total amount that circulates in the bloodstream. Normal reference range of the total triiodothyronine is 80 – 200 ng/dL. Below and above this range reflects an abnormality in secreting thyroid hormone and a functional problem of our thyroid gland.
When the total triiodothyronine level is high, we call this condition hyperthyroidism while when it is below, we call it hypothyroidism. Free triiodothyronine is a small percentage which is in the unbound form with proteins. Normal reference range of free triiodothyronine in our bloodstream is 2.3- 4.2 pg/mL. This level represents the immediately available triiodothyronine hormone which can be used. Hence, it is considered that free triiodothyronine is the best representation of the patient’s hormonal status. Furthermore, free triiodothyronine levels are important for the differential diagnosis of hyperthyroidism and non-thyroidal illnesses.
Triiodothyronine plays several vital roles in our body. It regulates the metabolic rate. It also regulates the heart and digestive functions, brain development and function, muscle and bones, etc.
- 甲状腺素和triiodothyronine are two hormones synthesized and released by the thyroid gland.
- They are tyrosine-based hormones.
- Production of both hormones decreases due to iodine deficiency.
- Both thyroxine and triiodothyronine are used to treat thyroid hormone deficiency (hypothyroidism).
- These hormones bind with thyroid hormone receptors in order to act.
甲状腺素和triiodothyronine are two thyroid hormones. However, thyroxine has four iodine atoms per molecule while triiodothyronine has three iodine atoms per molecule. Thus, this is the key difference between thyroxine and triiodothyronine. Furthermore, whole thyroxine originates from the thyroid secretion while most triiodothyronine originates from the deiodination of thyroxine.
The below infographic summarizes the difference between thyroxine and triiodothyronine.
摘要 - 甲状腺素与三碘甲醇
甲状腺素和triiodothyronine are two major hormones produced and released by the thyroid gland. However, the thyroid gland produces more thyroxine than triiodothyronine. The key difference between thyroxine and triiodothyronine is that thyroxine has four iodine atoms per molecule while triiodothyronine has three iodine atoms per molecule. Furthermore, whole thyroxine originates from the thyroid secretion while most triiodothyronine originates from thyroxine deiodination. This is the summary of the difference between thyroxine and triiodothyronine.