Difference Between Lactoferrin and Colostrum

Thekey differencebetween lactoferrin and colostrum is that乳铁蛋白是一种主要发生在人初乳中的糖蛋白，而初乳是哺乳动物的乳腺分泌的第一种牛奶。

Lactoferrin and colostrum are closely related terms because colostrum is rich with lactoferrin molecules. Lactoferrin is a glycoprotein, while colostrum is a form of milk.

内容

1.Overview and Key Difference
2.什么是乳铁蛋白
3.What is Colostrum
4.Lactoferrin vs Colostrum
5.摘要 - 乳铁蛋白与初乳

什么是乳铁蛋白?

Lactoferrin is a protein of the transferrin family. It is denoted by LF, and it is a球状糖蛋白摩尔质量约为80 kDa。该蛋白在牛奶，唾液，眼泪和鼻分泌物等各种分泌液中广泛代表。此外，这种化合物发生在PMNsand is also secreted by the acinar cells. We can purify lactoferrin from milk. Otherwise, we can produce it recombinantly. Generally, human colostrum contains the highest amount of lactoferrin protein.

Lactoferrin has antimicrobial activity, and it occurs as an innate defence such as mucose. Therefore, it occurs as a component ofour immune system。此外，该物质为人类婴儿提供抗菌活性。此外，该物质可以与DNA和RNA，多糖和肝素相互作用，显示该分子与配体配位复合物中的某些生物学功能。

This protein molecule is one of the transferrin proteins that can transfer iron into cells, and it can control the level of free iron in the blood and external secretions. We can find this substance occurring in blood plasma and neutrophils other than milk. It is one of the major proteins that is virtually an exocrine secretion in mammals.

What is Colostrum?

初乳是第一个从形式的牛奶the mammary glands of a mammal immediately after the delivery of a newborn. Typically, most species of mammals tend to produce colostrum before giving birth to the newborn. This first form of milk is very important because it has an especially high amount of bioactive compounds compared to mature milk. This is because it gives the newborn the best possible start of life.

Colostrum contains antibodies that help the newborn to fight against diseases and infections. Moreover, it and contains growth factors and other bioactive components, which helps the activation of the baby’s immune system. In addition, it allows the jumpstart of the gut system and causes the creation of a healthy gut microbiome in the first few days.

When considering the birth of a newborn, the newborn mammal is in a sterile environment inside the mother’s uterus, having a constant nutrient supply via the placenta. But after the birth, the baby is outside in a microbe-rich environment, and the newborn gets an irregular oral intake of milk which goes through the gastrointestinal tract. Therefore, colostrum has evolved to take care of highly sensitive mammalian neonates and also contributes to the initial immunological defence along with growth and development.

What is the Difference Between Lactoferrin and Colostrum?

乳铁蛋白和初乳是密切相关的术语，因为初乳富含乳铁蛋白分子。乳铁蛋白是一种糖蛋白，而初乳是牛奶的一种形式。乳铁蛋白和初乳之间的主要区别在于，乳铁蛋白是一种主要发生在人初乳中的糖蛋白，而初乳是哺乳动物乳腺分泌的牛奶的第一种形式。

The below infographic describes the differences between lactoferrin and colostrum in tabular form.

摘要 - 乳铁蛋白与初乳

乳铁蛋白是一种糖蛋白，而初乳是牛奶的一种形式。乳铁蛋白和初乳之间的主要区别在于，乳铁蛋白是一种主要发生在人初乳中的糖蛋白，而初乳是哺乳动物乳腺分泌的牛奶的第一种形式。

Reference:

1.“”BOVINE COLOSTRUM: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews。”WebMD, WebMD.

Image Courtesy:

1.“”Lactoferrin” lijealso - 使用蛋白质数据库（PDB：1B0L）的数据创建，并通过CONSONS WIKIMEDIA使用Pymol（公共领域）渲染
2. “Bovine colostrum and spray-dried colostrum powder” By Marguerita Briana Cattell – APSBioGroup(CC BY-SA 4.0)via Commons Wikimedia