Difference Between Keloid and Hypertrophic Scar

关键的区别——Keloid vs Hypertrophic Scar

超出原始伤口边界的疤痕称为乳子疤痕，而疤痕则在皮肤水平上方升高，但在原始伤口的边界内生长，称为肥大性疤痕。作为他们的定义，keloid scar grows out of the boundaries of the original wound but a hypertrophic scar grows within the boundaries of the original wound.This is the key difference between keloid scar and hypertrophic scar.

CONTENTS

1.Overview and Key Difference
2.What is a Keloid Scar
3.What is a Hypertrophic Scar
4.Similarities Between Keloid and Hypertrophic Scar
5.Side by Side Comparison – Keloid vs Hypertrophic Scar in Tabular Form
6.概括

What is a Keloid Scar?

When the epithelium is damaged either due to tissue injury or due to the loss of integrity of theepithelium细胞，修复机制自发激活。如果损害最小，修复会通过组织再生发生。但是，如果严重受伤或反复暴露于有害剂，则受损的组织会发炎。某些cytokinessuch as IL13 and TGF beta released by the inflamed cells stimulate the recruitment offibroblasts, which later differentiate into myofibroblasts. The end result is the formation of a fibrous tissue mass. This process is known asfibrosis.

Keloid scars are due to the excessive formation of these scar tissues. When the scar extends beyond the boundaries of the original wound and does not regress, it is called a keloid scar.

What is a Hypertrophic Scar?

Hypertrophic scars are also a result of the excessive formation ofcollagenfibers during wound healing. Although these scars are raised above the skin level, they do not grow beyond the boundaries of the original wound.

Treatment of Keloid and Hypertrophic Scars

• Surgical excision
• 冷冻疗法
• Compression therapy
• 放射治疗
• Occlusive Dressings
• Intralesional corticosteroid injections

What is the Similarity Between Keloid and Hypertrophic Scar?

• 两种类型的疤痕都是由于伤口愈合过程中胶原蛋白纤维过多的产生。

What is the Difference Between Keloid and Hypertrophic Scar?

Keloid vs Hypertrophic Scar
A scar that grows beyond the boundaries of the original wound is called a keloid scar.	A scar that is raised above the skin level but grows within the boundaries of the original wound is known as a hypertrophic scar.

概括– Keloid vs Hypertrophic Scar

A scar that grows beyond the boundaries of the original wound is called a keloid scar and a scar that is raised above the skin level but grows within the boundaries of the original wound is known as a hypertrophic scar. Unlike hypertrophic scars that grow within the limits of the original wound, a keloid scar grows beyond the boundaries of the original wound. This is the main difference between keloid scar and hypertrophic scar.

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参考：

1. Kumar, Vinay, Stanley Leonard Robbins, Ramzi S. Cotran, Abul K. Abbas, and Nelson Fausto. Robbins and Cotran pathologic basis of disease. 9th ed. Philadelphia, Pa: Elsevier Saunders, 2010. Print.

Image Courtesy:

1. “Keloid” By Michael Rodger – Own work(CC BY 3.0)viaCommons Wikimedia
2. “WhiteTailedSpiderBite” By Ezytyper at English Wikipedia – Transferred from en.wikipedia to Commons. (Public Domain) viaCommons Wikimedia