Key Difference – Endochondral Ossification vs Intramembranous Ossification
成骨的发生，通常称为骨化，是一个新层的过程骨纸巾由成骨细胞。骨骨化与骨钙化过程不同。这是一个涉及细胞和组织中钙的盐的铺设的过程。正常的骨骨化过程可以是两种不同类型的：内侧软骨骨化和膜内骨化。在软骨骨化期间，软骨is utilized as a precursor for bone formation.在膜内骨化中，骨组织直接放在原始connective tissue称为间充质没有中间软骨的参与。This is the key difference between endochondral ossification and intramembranous ossification. In the context offractures, the healing process by plaster of Paris occurs through endochondral ossification whilst the fractures which are treated by open reduction and internal fixation get healed by intramembranous ossification.
1。Overview and Key Difference
3.What is Intramembranous Ossification
4.Similarities Between Endochondral Ossification and Intramembranous Ossification
5。Side by Side Comparison – Endochondral Ossification vs Intramembranous Ossification in Tabular Form
内侧软骨骨化是一个对于形成长骨（股骨）和平坦和不规则骨骼的过程，例如ribs和vertebrae。Endochondral ossification is a process that involves two main functions; it is involved in the natural growth of bones and its lengthening and is also involved in the healing of bone fractures naturally. During this type of ossification process, which leads to the formation of long bones and other types of bones, the involvement of a cartilage precursor takes place. The whole ossification process takes place in two centres of ossification, primary and secondary.
In the primary centre of ossification first site of ossification which leads to the formation of the mid-region of the long bone is diaphysis.骨干is the region where the bone tissue first appears in long bones. In the primary ossification centre,成骨细胞和破骨细胞吸收软骨由chondrocytes根据软骨网络，这导致骨骼铺设。重要的是要提到软骨不是转化为骨头，而是充当前体。一旦小梁骨形成，软骨就被硬化的骨头代替，并延伸到长骨的末端。epiphysis。二次骨化中心围绕着附着分析区域。次级骨化中心具有与一级骨化中心相似的功能。主要骨化中心和次级骨化中心之间未修解的软骨称为软骨板或顿悟板。
What is Intramembranous Ossification?
Intramembranous ossification is a type of bone ossification process that doesn’t involve a cartilage precursor, but the bone tissue is directly formed over the mesenchymal tissue. Intramembranous ossification is a process which leads to the formation of jaw bones, collar bones or clavicles. It is also involved in the primary formation of skull bones and occurs during the healing of bone fractures. The bone formation during intramembranous ossification is initiated by the mesenchymal cells that are present within the medullary cavity of a bone fracture.
一小部分相邻的间充质干细胞开始复制并形成一个称为A的细胞簇nidus。一旦形成了Nidus，就会停止这种复制过程，并且间充质干细胞的形态变化的发展开始发生。更改包括细胞体变得更大和数量的增量rough endoplasmic reticulum和Golgi apparatus。These developed cells are known as骨基因细胞。The osteoprogenitor cells undergo different morphological changes to become osteoblasts. An extracellular matrix is formed by osteoblasts which contain osteoid, a1型胶原蛋白。
骨细胞形成oste整合oblasts within the osteoid. The bone tissue and bone spicules are developed due to the mineralization process. Due to the increase in secretion of the osteoid, the size of spicules is increased, which leads to the formation of trabeculae due to the fusion of spicules with each other. As the growth continues, the trabeculae get interconnected and form woven bones. The periosteum is formed around the trabeculae; this leads to the origination of osteogenic cells which forms the bone collar. Finally, the lamellae bone replaces the woven bone.
What is the Similarity Between Endochondral Ossification and Intramembranous Ossification?
- Both processes are involved in the formation of bone tissue and healing of bone fractures.
What is the Difference Between Endochondral Ossification and Intramembranous Ossification?
|在软骨骨化期间，软骨is utilized as a precursor for bone formation.
|The fractures which are treated by open reduction and internal fixation get healed by intramembranous ossification.
Summary – Endochondral Ossification vs Intramembranous Ossification
Osteogenesis is a process by which new layers of bone tissues are laid by osteoblasts. A normal bone ossification process can be of two different types; endochondral ossification and intramembranous ossification. During endochondral ossification, cartilage is utilized as a precursor for bone formation. In intramembranous ossification, the bone tissue is directly laid on a primitive connective tissue referred to as mesenchyma without the involvement of an intermediate cartilage. This is the difference between endochondral ossification and intramembranous ossification.
You can download PDF version of this article and use it for offline purposes as per citation note. Please download PDF version here内侧软骨骨化和膜内骨化之间的差异
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