Thekey difference在细胞介导的和抗体介导的免疫之间，是cell mediated immunity destroys infectious particles via cell lysis bycytokines, without the production ofantibodies，而抗体介导的免疫破坏pathogensby producing specific antibodies against antigens.
Cell mediated immunity and antibody mediated immunity are two types of primary defence mechanisms taking place in our body. Cell mediated immunity operates against intracellular pathogens. Hence, it works inside infected cells and destroys pathogens by releasing cytokines. In contrast, antibody mediated immunity operates against extracellular pathogens by producing antibodies against the antigens present outside the infected cells or free circulating in the blood. Moreover,B lymphocytes主要执行抗体介导的免疫力T lymphocytes进行细胞介导的免疫力。
1.Overview and Key Difference
2.What is Cell Mediated Immunity
4.Similarities Between Cell Mediated and Antibody Mediated Immunity
5.Side by Side Comparison – Cell Mediated vs Antibody Mediated Immunity in Tabular Form
What is Cell Mediated Immunity?
Antibody mediated immunity, as the name implies, occurs via the production of antibodies. It specifically responds to antigens that are freely circulating or present outside the infected cells. When an antigen enters into our serum with the help of helper T cells, B lymphocytes differentiate into plasma cells. Plasma cells proliferate, and all proliferated plasma cells produce specific antibodies against the antigens. Antibodies bind with antigens and neutralize or deactivate them or cause lysis.
Antibodies are immunoglobulin proteins. There are five types of antibodies as IgA, IgG, IgM, IgE and IgD. IgG is the most abundant type of antibody. Antibodies diminish after they deactivate antigens. However, B lymphocytes produce memory cells when they encounter an antigen. These memory cells produce plasma cells and antibodies rapidly and intensely when we are exposed to the same antigen the second time. Therefore, antibody mediated immunity provides long-lasting immunity for specific antigens.
- Cell mediated and antibody mediated immunity are two categories of adaptive immunity.
- They are primary defence mechanisms.
- Both types of immunity usually develop concurrently体内, and the two responses often act synergistically.
Cell mediated immunity is facilitated by T lymphocytes via the release of cytokines while antibody mediated immunity is facilitated by B lymphocytes via the production of antibodies. So, this is the key difference between cell mediated and antibody mediated immunity. Cell mediated immunity works against intracellular pathogens while antibody mediated immunity works against extracellular pathogens. Furthermore, cell mediated immunity creates a delayed response, while antibody mediated immunity creates a rapid response. This is also a difference between cell mediated and antibody mediated immunity.
下面的图表总结了不同tween cell mediated and antibody mediated immunity.
摘要 - 细胞介导的VS抗体介导的免疫力
1. Janeway, Charles A, and Jr. “T Cell-Mediated Immunity.” Immunobiology: The Immune System in Health and Disease. 5th Edition., U.S. National Library of Medicine, 1 Jan. 1970,Available here.
2. “Humoral Immunity.” Wikipedia, Wikimedia Foundation, 7 Sept. 2019,Available here.
1. “T cell activation” By T_cell_activation.png: Template drawing and caption text from “The Immune System”, (Public Domain) viaCommons Wikimedia
2. “B cell activation” By Fred the Oysteri (Public Domain) viaCommons Wikimedia