Antimicrobialsubstances have the ability to kill pathogenic microorganisms or retard their growth and reproduction. Antimicrobials can be antibacterial, antifungal or antiviral. Antibacterial substances or antibiotics work against bacteria while antifungal substances work against pathogenic fungi. Antiviral drugs kill viruses. Therefore, antibiotics are a type of most effective antibacterial substances that can be used to combat bacterial infections. Bacteriocin is a proteinaceous toxin produced by bacteria. It works against closely related bacterial strains. Thus, both antibiotic and bacteriocin possess antibacterial activity.
Bacteriocin is a proteinaceous toxin produced by bacteria to inhibit another closely related bacterium. In fact, they are antibacterial peptides produced by the translation process occurring in ribosomes. Hence, they are ribosomally originated substances. Since bacteriocins can pose antimicrobial activity only against closely related bacterial strains, their antibacterial activity is a narrow spectrum.
Furthermore, bacteriocins are high molecular weight peptides. Lactic acid bacteria produce a range of bacteriocins. Moreover, bacteriocin producing bacteria are insusceptible for bactericidal agents, unlike antibiotic-producing bacteria. Bacteriocins can be used as narrow-spectrum antibiotics to treat bacterial diseases.
An antibiotic is an antibacterial substance that either kills or inhibits the growth of bacteria. Therefore, an antibiotic works against bacteria. Bactericidal antibiotics kill bacteria, while bacteriostatic antibiotics inhibit the growth of bacteria. They cannot kill viruses. Antibiotics are popular drugs used today in treating many types of bacterial diseases. Alexander Fleming discovered the first natural antibiotic ‘penicillin’ in 1928 through his experiments. Ampicillin, amoxicillin, and penicillin G are several penicillin-based antibiotics. Soil bacteria and fungi produce antibiotics naturally. These antibiotics are able to differentiate host cells and bacterial cells. Hence, they specifically act only against bacterial cells.
- Bacteria produce bacteriocins and antibiotics.
- Since they have antimicrobial activity, they can be used as drugs to treat bacterial diseases.
The below infographic summarizes the difference between bacteriocin and antibiotic.
概括– Bacteriocin vs Antibiotic
Bacteriocins are proteinaceous toxins produced by bacteria against closely related bacterial strains while antibiotics are antibacterial agents that destroy or slow down the growth of bacteria. Therefore, both bacteriocins and antibiotics have antibacterial activity. But, bacteriocins have a narrow spectrum antibacterial activity while antibiotics have a broad-spectrum antibacterial activity. Furthermore, bacteriocins are high molecular weight peptides produced by the translation process, while antibiotics are low molecular weight secondary metabolites. So, this is the summary of the difference between bacteriocin and antibiotic.