What is the Difference Between Serum Iron and Ferritin

The血清铁和铁蛋白之间的关键区别is that serum iron is the amount of circulating iron bound to transferrin and serum ferritin, while ferritin is an intracellular protein that stores iron in the cell and releases it in a controlled manner.

Iron is an essential nutrient. It has many functions, such as the production of healthy红细胞。这是血红蛋白的重要组成部分。人体不能单独生产铁，因此必须从食物和补充剂中吸收铁。通常，铁通过称为蛋白质在体内运输transferrin。In healthy people, most of the iron in the body is incorporated intohaemoglobinin red blood cells. The remaining iron is stored in ferritin. Therefore, serum iron and ferritin help to evaluate iron in the body.

内容

1.Overview and Key Difference
2.什么是血清铁
3.What is Ferritin
4.相似性 - 血清铁和铁蛋白
5。血清铁与铁蛋白的表格形式
6。概括

什么是血清铁？

Serum iron is the amount of circulating iron bound to transferrin and serum ferritin. Serum iron test measures this amount of circulating iron. Normally, 90 % of serum iron is bound to transferrin transport protein. The rest of the 10 % of serum iron is stored in ferritin. Doctors order this test when they suspect an iron deficiency. Iron deficiencies can cause anaemia and other health problems. Usually, 65 % of the iron in the body is in the haemoglobin in red blood cells. Approximately 4 % is in肌红蛋白molecules. Around 30 % of iron is stored in ferritin or hemosiderin in the spleen, bone marrow and liver. A small amount of iron can be found in other molecules in the cells. None of this iron is directly accessible through testing the serum. Anyhow, some iron is circulating in the serum. Transferrin is a molecule produced by the liver that binds to one or two irons. Circulating iron is mainly bound to transferrin protein. The test for serum iron measures the iron ions that are bound to transferrin and stored in serum ferritin. Moreover, the normal serum iron reference ranges for men are 65 to 176 μg/dL and for women are 50 to 170 μg/dL.

Serum iron test is an important tool for the diagnosis process of conditions such as anaemia, iron deficiency anaemia, anaemia of chronic disease and haemochromatosis.

什么是铁蛋白？

Ferritin is an intracellular protein that stores iron in the cell and releases it in a controlled manner. It is a globular protein complex. The ferritin test measures the amount of ferritin in the blood. This is an indirect measurement of circulating iron that is bound to or stored in serum ferritin. This protein is produced by almost all living organisms. It keeps iron in soluble and non-toxic form.

铁蛋白在大多数组织中作为胞质蛋白产生。少量分泌到血清中充当铁载体的血清。此外，血清铁蛋白是铁缺乏贫血的诊断测试。男性血液中的正常铁蛋白参考范围为18-270 ng/ml，女性为30-160 ng/ml。

What are the Similarities Between Serum Iron and Ferritin?

• Both terms are related to iron.
• 它们对于测量循环铁的总量非常重要。
• Both can be measured by using blood through specific laboratory tests.
• These are diagnostic markers for iron deficiency anaemia.

What is the Difference Between Serum Iron and Ferritin?

Serum iron is the amount of circulating iron bound to transferrin and serum ferritin, while ferritin is an intracellular protein that stores iron in the cell and releases it in a controlled manner. So, this is the key difference between serum iron and ferritin. Furthermore, serum iron is measured through serum iron test, while ferritin is measured through serum ferritin or ferritin test.

The following infographic tabulates the difference between serum iron and ferritin for side by side comparison.

摘要 - 血清铁与铁蛋白

Iron is an important mineral the body uses for growth and development. Serum iron and ferritin help to evaluate iron in the body. Serum iron is the amount of circulating iron that is bound to transferrin and serum ferritin, while ferritin is an intracellular protein that stores iron in the cell and releases it in a controlled manner. Thus, this is the summary of the difference between serum iron and ferritin.

Reference:

1. Soldin, Offie P, et al.“Serum Iron, Ferritin, Transferrin, Total Iron Binding Capacity, Hs-CRP, LDL Cholesterol and Magnesium in Children; New Reference Intervals Using the Dade Dimension Clinical Chemistry System。”Clinica Chimica Acta;国际临床化学杂志，美国国家医学图书馆。
2.“铁蛋白血液测试:MedlinePlus Medical Test。”美国国家医学图书馆Medlineplus。

Image Courtesy:

1.“”Iron-deficiency Anemia, Peripheral Blood Smear“ 经过Ed Uthman（CC由2.0）通过Flickr
2. “Ferritin” (GPL) via Commons Wikimedia