Compare the Difference Between Similar Terms

Difference Between

Home / Science & Nature / Science / Biology / Immunology /What is the Difference Between Mature and Immature Lymphocytes

What is the Difference Between Mature and Immature Lymphocytes

May 3, 2022Posted byHasa

Thekey differencebetween mature and immature lymphocytesis that the mature lymphocytes have the ability to fight against infections in the body, while the immature lymphocytes do not have the ability to fight against infections in the body.

A lymphocyte is a type of white blood cell that is a part of theimmune system. Based on their function, there are three main types of lymphocytes:B cells, T cells和自然杀伤细胞。B细胞产生antibodies to attack invading bacteria, viruses, and toxins. T cells destroy body’s own cells that have been taken over by viruses or become cancerous in nature. Natural killer cells function in cell-mediated cytotoxic innate immunity. However, based on their maturation, lymphocytes are categorized into two types as mature and immature lymphocytes. Immature lymphocytes are precursors to mature lymphocytes.

CONTENTS

1.Overview and Key Difference
2.What are Mature Lymphocytes
3.What are Immature Lymphocytes
4.Similarities – Mature and Immature Lymphocytes
5.Mature vs Immature Lymphocytes in Tabular Form
6.Summary – Mature vs Immature Lymphocytes

What are Mature Lymphocytes?

Mature lymphocytes have the ability to fight against infections in the body. Mature lymphocytes arewhite blood cellsthat travel through the lymphatic system and help humans and other animals fight against numerous diseases. There are three main lymphocytes, including B cells, T cells, and natural killer cells. All these cells originate from the bone marrow. But some travel to different areas of the body to mature. They also perform different functions. However, these lymphocytes generally attack invasive cells and tissue.

Mature vs Immature Lymphocytes in Tabular Form

Figure 01: Mature Lymphocytes

B cells develop in the bone marrow and mature there as well. Mature B cells then constantly travel throughout the body. When they detect an invader in the body, B cells turn to plasma cells that produce antibodies. This is called a humoral response. T cells are developed by stem cells in the bone marrow. Then they travel to the thymus gland, where they mature completely. Later these T cells travel to lymph nodes, where they are transferred to the bloodstream if necessary. The majority of T cells are extremely small, but a handful of these cells grows to about twice the size of the rest. All mature T cells take care of cell-mediated adaptive immunity.

Initially, it was thought the natural killer cells were developed exclusively in the bone marrow. But recent studies suggest they also can develop and mature in secondary lymphoid tissues (SLTs), including tonsils, spleen, and lymph nodes. Natural killer cells are the predominant innate lymphocyte subsets that normally mediate anti-tumor and anti-viral responses.

What are Immature Lymphocytes?

Immature lymphocytes do not have the ability to fight against infection in the body. They predominantly originate from the stem cells of the bone marrow. They can also refer to immature cells that typically differentiate to form mature lymphocytes.

Mature and Immature Lymphocytes - Side by Side Comparison

Figure 02: Hematopoiesis

Immature lymphocytes are activated by antigens from antigen-presenting cells and increased in volume by the nucleus and cytoplasm growth, as well as new mRNA and protein synthesis. They start dividing two to four times every 24 hours for three to five days, where a single immature lymphocyte makes approximately 1000 clones of its original naive lymphocyte. Finally, the dividing cells differentiate into effector cells (mature lymphocytes) known as plasma cells (B cells), cytotoxic T cells, T helper cells, and mature natural killer cells.

What are the Similarities Between Mature and Immature Lymphocytes?

  • Mature and immature lymphocytes are two types of lymphocytes based on maturation.
  • Immature lymphocytes are precursors to mature lymphocytes.
  • Both types can be found in the bone marrow.
  • They can be converted to cancer cells.

What is the Difference Between Mature and Immature Lymphocytes?

Mature lymphocytes have the ability to fight against infection in the body, while immature lymphocytes lack the ability to fight against infection in the body. Thus, this is the key difference between mature and immature lymphocytes. Furthermore, mature lymphocytes are found in bone marrow, thymus, lymph nodes, bloodstream, tonsils, and spleen. On the other hand, immature lymphocytes are predominantly found in the bone marrow and rarely secondary lymphoid tissues (SLTs).

The below infographic presents the differences between mature and immature lymphocytes in tabular form for side by side comparison.

Summary – Mature vs Immature Lymphocytes

Mature and immature lymphocytes are two types of lymphocytes based on maturation. Mature lymphocytes have the ability to fight against infection in the body, while immature lymphocytes do not have the ability to fight against infection in the body. So, this is the key difference between mature and immature lymphocytes.

Reference:

1. “What Are Mature Lymphocytes?” Wise Geek.
2. “Lymphoblast.” Encyclopædia Britannica, Encyclopædia Britannica, Inc.

Image Courtesy:

1. “Plasma cells” By Department of Pathology, Calicut Medical College – Calicut Medical College(CC BY-SA 4.0)via Commons Wikimedia
2. “Hematopoiesis (human) diagram” By A. Rad – Own work(CC BY-SA 3.0)via Commons Wikimedia

Related posts:

Difference Between Macrophages and Dendritic Cells Difference Between Serum and AntiserumDifference Between Serum and Antiserum Key Difference - Opsonization vs NeutralizationDifference Between Opsonization and Neutralization Difference Between Variolation and VaccinationDifference Between Variolation and Vaccination Difference Between Herd and Ring ImmunityDifference Between Herd and Ring Immunity

Filed Under:Immunology

About the Author:Hasa

哈萨是英航人文领域的研究生nd is currently pursuing a Master's degree in the field of English language and literature. Her areas of interests include language, literature, linguistics and culture.

Leave a ReplyCancel reply

Your email address will not be published.Required fields are marked*

Request Article

Featured Posts

Difference Between Coronavirus and Cold Symptoms

Difference Between Coronavirus and Cold Symptoms

Difference Between Coronavirus and SARS

Difference Between Coronavirus and SARS

Difference Between Coronavirus and Influenza

Difference Between Coronavirus and Influenza

Difference Between Coronavirus and Covid 19

Difference Between Coronavirus and Covid 19

You May Like

Difference Between Marginal Analysis and Break Even Analysis

Difference Between Marginal Analysis and Break Even Analysis

Difference Between Neutrophils and Macrophages

Difference Between Neutrophils and Macrophages

Difference Between QuickBooks and Quicken

Difference Between Gelato and Ice Cream

Difference Between Gelato and Ice Cream

Difference Between Success and Failure

Latest Posts

  • What is the Difference Between Cellulite and Lipedema
  • What is the Difference Between Kinetin and Zeatin
  • What is the Difference Between Benzoyl Peroxide and Benzyl Benzoate
  • What is the Difference Between Sebum and Sweat
  • What is the Difference Between L Carnitine and Acetyl L Carnitine
  • What is the Difference Between Orthostatic Hypotension and Vasovagal Syncope
  • Home
  • Vacancies
  • About
  • Request Article
  • Contact Us

Copyright © 2010-2018Difference Between. All rights reserved.Terms of Useand Privacy Policy:Legal.