什么is the Difference Between Bronchiectasis and Cystic Fibrosis

Thekey differencebetween bronchiectasis and cystic fibrosisis that bronchiectasis is a long-term condition where the支气管的lungs永久扩大，而囊性纤维化是一种对体内肺，消化系统和其他器官造成严重损害的疾病。

Lung diseases are the most common medical conditions in the world. Generally, smoking, infections, and genes are the main causes of lung diseases. Lung diseases occur when there are problems in any part of the呼吸系统. Bronchiectasis and cystic fibrosis are two conditions that affect the airways of the lungs.

内容

1.Overview and Key Difference
2.什么是支气管扩张
3.什么is Cystic Fibrosis
4.相似性 - 支气管扩张和囊性纤维化
5.Bronchiectasis vs Cystic Fibrosis in Tabular Form
6。Summary – Bronchiectasis vs Cystic Fibrosis

什么是支气管扩张?

Bronchiectasis is a long-term condition where the bronchi of the lungs become permanently damaged and widened. This widening leads to the build-up of excess粘液, which can make the lungs more vulnerable to infections by pathogens. Normally, bronchiectasis happens if the tissue and muscles that surround the bronchi are damaged. The three most common causes for the damages are: having had a lung infection in the past like pneumonia, whooping cough, and underlying problems with the immune system that make bronchi vulnerable to infection and aspergillosis (an allergy to a certain type of fungi). However, in many cases, no exact cause for this condition can be found. This is known asidiopathic bronchiectasis.

The symptoms of bronchiectasis include coughing up yellow or green mucus daily, shortness of breath, fatigue, fevers, and chills, wheezing, whistling sound while breathing, and coughing up blood or mucus mixed with blood (hemoptysis). Moreover, this medical condition can be diagnosed through lung function tests, X-rays, CT-scan, and bronchoscopies. Treatments include exercises and special devices to help clear mucus out of the lungs, medicine like roflumilast to help improve airflow in the lungs, and antibiotics to treat any lung infections. In rare cases, surgery is considered for bronchiectasis.

什么is Cystic Fibrosis?

囊性纤维化是一种遗传疾病，会对体内的肺，消化系统和其他器官造成严重损害。在这种情况下，粘性粘液在肺部和消化系统中积聚。囊性纤维化发生是由于称为CFTR的基因中的突变。该基因通常控制盐和流体进出细胞的流动。如果CFTR基因不起作用，则粘性粘液在体内积聚。

这种疾病的症状包括重复出现的胸部感染，喘息，咳嗽，呼吸急促，减轻体重和生长的困难，眼睛的皮肤和白色部分，腹泻，便秘，便秘和新生儿的肠梗阻。可以通过新生儿血点测试，座椅测试和CFTR基因的遗传测试来诊断这种疾病。此外，对这种疾病的治疗可能包括药物，例如囊性纤维化跨膜电导调节剂（CFTR），调节剂（Elexacaftor，ivacaftor，tezacaftor），肺部感染的抗生素，抗炎药，以减少抗炎药，以减少空气，支气管，良好的空气旋转剂的肿胀。，口服胰腺酶有助于消化道吸收营养，凳子软化剂以减轻便秘和肠梗阻，酸还原药物，以帮助消化酶正常运行，并为肝病的特定药物发挥作用。有时，也可能建议进行鼻和鼻窦手术，肠道手术，肺移植和肝移植等手术。

什么are the Similarities Between Bronchiectasis and Cystic Fibrosis?

• Bronchiectasis and cystic fibrosis are two lung diseases.
• Both medical conditions can affect the airways of the lungs.
• Sometimes, both medical conditions may show similar symptoms such as wheezing, coughing, shortness of breath.
• Sometimes, both medical conditions may use similar treatment options, such as the usage of antibiotics and anti-inflammatory drugs.

支气管扩张和囊性纤维化有什么区别？

Bronchiectasis is a long-term condition where the bronchi of the lungs become permanently widened, while cystic fibrosis is an inherited condition that causes severe damage to the lungs, digestive system, and other organs in the body. Thus, this is the key difference between bronchiectasis and cystic fibrosis. Furthermore, bronchiectasis is mainly caused due to past lung infections like pneumonia, whooping cough, underlying problems with the immune system, and aspergillosis. On the other hand, cystic fibrosis is caused due to inherited genetic mutation of the CFTR gene.

The below infographic presents the differences between bronchiectasis and cystic fibrosis in tabular form for side by side comparison.

Summary – Bronchiectasis vs Cystic Fibrosis

Bronchiectasis and cystic fibrosis are two medical conditions that affect the airways of the lungs. Bronchiectasis is a long-term condition where the bronchi of the lungs become permanently widened, while cystic fibrosis is an inherited condition that causes severe damage to the lungs, digestive system, and other organs in the body. So, this is the key difference between bronchiectasis and cystic fibrosis.

Reference:

1.“”了解支气管扩张.” American Lung Association.
2. “Cystic Fibrosis.” Mayo Clinic, Mayo Foundation for Medical Education and Research.

Image Courtesy:

1.“”Bronchiectasis”布鲁库布劳（Bruceblaus） - 自己的作品(CC BY-SA 4.0)通过Commons Wikimedia
2. “Blausen 0286囊性纤维化” Blausen.com员工（2014年）。“ Blausen Medical 2014的医学画廊” Wikijournal of Medicine 1（2）。doi：10.15347/wjm/2014.010。ISSN 2002-4436。- 自己的工作(CC BY 3.0)通过Commons Wikimedia