Key Difference – Multiple Sclerosis vs Systemic Sclerosis Both multiple sclerosis and systemic sclerosis are autoimmune diseases whose pathogenesis is triggered by undiscovered environmental and genetic factors. Multiple Sclerosis is a chronic autoimmune, T-cell mediated inflammatory disease affecting the central nervous system whereas systemic sclerosis, also known as scleroderma, is an autoimmune multisystem disease […]