Difference Between Pseudomonas and Staphylococcus

Thekey differencebetweenPseudomonasandStaphylococcusis thatPseudomonasis a genus ofGram-negativerod-shaped Gamma-proteobacteriabelonging to the familyPseudomonadaceaewhileStaphylococcusis a genus ofGram-positivespherical bacteria belonging to the familyStaphylococcaceae。

PseudomonasandStaphhlococcusare two clinically important bacterial genera。Pseudomonasis a genus of rod-shaped, polar-flagellated bacteria with some sporulating species.Pesudomonasdemonstrates a great deal of metabolic diversity and is able to colonize a wide range of niches.Staphylococcusis a genus of spherical shaped bacteria that reside on the skin and mucous membranes of human and other animals.

CONTENTS

1.Overview and Key Difference
2.What is Pseudomonas
3.What is Staphylococcus
4.Similarities Between Pseudomonas and Staphylococcus
5.Side by Side Comparison – Pseudomonas vs Staphylococcus in Tabular Form
6.Summary

What isPseudomonas?

Pseudomonasis a genus of bacteria that belong to the family ofPseudomonadaceae。This family comprises about 191 different known species. Pseudomonas bacteria are present in humans, water and plants, including dicots. The well-known species includeP. aeruginosa(an opportunistic pathogen in human),P. syringae(a plant pathogen),P. putida(a soil species), and several growth-promoting species in plants such asP. fluorescens,p .林i,P. migulae, andP. Graminis,etc.

They were first classified and identified by Walter Migula. The complete genome sequence ofPseudomonasspecies was determined in 2000. According to that, their genome size is ranging from 5.5 to 7 Mbp (P. aeruginosa).Pseudomonasspecies have other characteristics: they are aerobic, non-spore-forming, catalase-positive and oxidase-positive. Of many differentPseudomonasspecies, the one that more frequently causes diseases in human isP. aeruginosa。P. aeruginosacan cause infections in the blood, lungs (pneumonia) or another part of the body after surgery. In 2017, multidrug-resistantP. aeruginosacaused 32600 estimated hospitalized infections and 2700 estimated deaths in the United States.

What isStaphylococcus?

Staphylococcusis a genus of Gram-positive spherical-shaped bacteria in the family ofStaphylococcaceae.Staphylococcuswas first discovered in 1880 by the Scottish surgeon and bacteriologist Alexander Ogston.Staphylococcusgenus has at least 40 species. Of these, nine have two subspecies, one has three subspecies, and one has four subspecies. The majority ofStaphylococcusspecies do not cause diseases, and they reside on the skin and mucous membranes of human and other animals. Based on orthologous genes content,Staphylococcusis divided into three main groups: Group A, Group B, Group C.

The genome size ofStaphylococcus(S. aureus) is approximately 2.8 Mbp coding for 2,614 open reading frames.Staphylococcuscauses diseases by direct tissue infections and by exotoxin productions. Direct tissue infections are more common and include skin infection, pneumonia, endocarditis, osteomyelitis and infectious arthritis. Toxin-mediatedStaphylococcaldiseases include toxic shock syndrome,Staphylococcalscalded skin syndrome andStaphylococcalfood poisoning.Staphylococcusspecies are highly antibiotic-resistant. Methicillin-resistantS. Aureusis one example. Some strains are partially or totally resistant to the newest antibiotics such as linezolid, tedizolid, quinupristin, daptomycin, telavancin, dalbavancin, oritavancin, tigecycline, eravacycline, omadacycline, delafloxacin, ceftobiprole, lefamulin, etc.

What are the Similarities BetweenPseudomonasandStaphylococcus?

• BothPseudomonas andStaphylococcusare bacteria that are prokaryotic organisms.
• They cause diseases in human.
• They are microorganisms.
• Both are multidrug-resistant (antibiotics) bacteria.

What is the Difference BetweenPseudomonasandStaphylococcus?

Pseudomonasis a genus of Gram-negative rod-shaped Gamma-proteobacteria belonging to the family ofPseudomonadaceae。On the other hand,Staphylococcusis a genus of Gram-positive spherical-shaped bacteria in the family ofStaphylococcaceae。So, this is the key difference betweenPseudomonasandStaphylococcus。Pseudomonasshows a wide distribution, including water, plants (dicots), and human bodies. Whereas,Staphylococcusis predominantly found in the skin and mucous membranes of human and other animals.

Moreover, Pseudomonascauses diseases such as urinary tract infections, respiratory system infections (pneumonia), dermatitis, soft tissue infections, bacteraemia, bone and joint infections, gastrointestinal infections, and systematic infections in patients with burns and cancer in those who are immunocompromised. Meanwhile,Staphylococcuscauses skin infection, pneumonia, endocarditis, osteomyelitis, infectious arthritis, toxic shock syndrome,Staphylococcalscalded skin syndrome, and food poisoning.

The below infographic lists more differences betweenPseudomonasandStaphylococcusin tabular form.

Summary –PseudomonasvsStaphylococcus

Pseudomonasis a genus of Gram-negative rod-shaped Gammaproteobacteria. They belong to the familyPseudomonadaceae。Staphylococcusis a genus of Gram-positive spherical-shaped bacteria in the family ofStaphylococcaceae。Thus, this is the key difference betweenPseudomonasandStaphylococcus。由于他们不同的基因组变异,cause different diseases in human and other animals. Both genera include respiratory pathogens.

Reference:

1. Foster, Timothy. “Staphylococcus.” Medical Microbiology. 4th Edition., U.S. National Library of Medicine, 1 Jan. 1996,Available here。
2. “Pseudomonas.” Wikipedia, Wikimedia Foundation, 1 Mar. 2021,Available here。

Image Courtesy:

1. “Scanning, electron micrograph, pseudomonas aeruginosa, bacteria” (CC0) viaPixino
2. “High, magnification, 10000x, strain, staphylococcus aureus, bacteria” (CC0) viaPixino