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之间的区别Panadol and Aspirin

February 26, 2011Posted by奥利维亚

Panadol vs阿司匹林

Panadol和阿司匹林在反药物上,通常用于治疗发烧和疼痛。Panadol通常被称为扑热息痛和阿司匹林(乙酰水杨酸)都属于药物的镇痛药类别,具有抗炎和疼痛的特性。Panadol在环氧合酶上起作用,对酶的COX-2变体有更多亲和力。扑热息痛减少了Cox酶的氧化形式,从而防止了促炎性化学物质。阿司匹林在相同的酶和乙酰酸盐上工作时,其与乙酰基团共价。两种药物使用的主要用途是发烧流感和酸痛。阿司匹林还用于冠状动脉疾病,以及矫正疗法以及预防心脏病发作和中风,因为它充当血液囊剂。

Panadol

帕纳多(Panadol)在处方的柜台药物上出于发烧和头痛。它于1893年引入。PANADOL主要抑制环氧合酶的COX-2变体,该变异酶的COX-2变体负责蛛网膜酸对前列腺素H2的代谢,前列腺素H2,这是一种不稳定的分子,这反过来又转化为许多其他促炎性化合物。因此导致炎症缓解。它可在片剂,胶囊,液体悬浮液,栓剂,静脉内和肌肉内形式可用,具体取决于处方。常见的成人剂量为每天500毫克至1000毫克。与阿司匹林和布洛芬等其他NSAID相比,它具有低抗炎特性。它在市场上也可以与慢性疼痛的鸦片结合使用。Panadol的主要不利作用是高剂量时胃肠道并发症,对孕妇和儿童是安全的。一些研究表明它与哮喘的关联。

阿司匹林

阿司匹林最常用的药物用于头痛。它作用于环氧酶酶,并抑制其产生前列腺素的作用,从而缓解疼痛和炎症。它比Panadol更强大。Panadol缓解头痛是有道理的。在某些组合药物中,它与Panadol和Caffeine结合使用,具有更高的功效。它是针对头痛,疼痛,发烧,普通感冒和预防中风和心脏病发作的规定。它仅在某些国家 /地区的特定指示中用于儿童,因为其毒性高于可用的替代品。主要的不利影响是胃肠道出血,耳鸣和雷耶综合征。

Panadol和阿司匹林之间的区别

这两种药物处方几乎是类似的,target of action and the effects and belongs to the same class of NSAIDS in the analgesics classification. Some authors have described Panadol as a different agent within the same class. However the extent of action is different for both of them. While Panadol is preferred for the fever and flu in younger patients Aspirin is not commonly for use of pediatric patients. Panadol is much safer in these cases. Aspirin acts on the stomach wall and increase the risk of gastrointestinal bleeding while panadol has very little risk in this regard. However Aspirin is very useful in the patients with the risk of cardiac ischemia and stroke as it can lower the risk upto 8%. It also has the effect in the prevention of deep vein thrombosis as it hinders the production of thromboxane.

Conclusion

对于普通流感头痛和发烧panadol的处方,由于其低不良效应特征,因此是首选药物。但是,在某些情况下,阿司匹林对小儿患者的风险更为有效。阿司匹林指示的抗血栓性活性和心脏作用是不可避免的,因为它具有挽救生命的潜力,并具有最低风险。

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提交以下:Nutrients & DrugsTagged With:Analgesics class of drugs,,,,阿司匹林,,,,blood thining agent,,,,心脏缺血,,,,Coronary arteries disorders,,,,Cox酶,,,,COX-2变体,,,,cyclooxygenase,,,,high toxicity,,,,布洛芬,,,,NSAIDS,,,,Opiates,,,,over-the-counter drugs,,,,painkillers,,,,Panadol,,,,扑热息痛,,,,pediatric patients,,,,预防深静脉血栓形成,,,,risk of gastrointestinal bleeding,,,,Panadol的副作用,,,,stroke,,,,血栓烷,,,,使用阿司匹林

关于作者:奥利维亚

奥利维亚is a Graduate in Electronic Engineering with HR, Training & Development background and has over 15 years of field experience.

Comments

  1. Dr Gurusays

    2011年2月26日上午6:10

    基本上,对扑热息痛不被医生视为NSAID。它是中央作用的药物。它具有抗抑郁(反对发烧)的抗镇痛作用(反对油漆)和非常轻度的抗炎(反对炎症)药物。通用名称是扑热息痛。品牌名称(商品名是panadol,paracetol等)

    阿司匹林最初用于发烧的NSAID不用于预防心脏病。高剂量(每天300毫克300毫克)的阿司匹林可抵抗发烧,但副作用很高。但是,以较低剂量(仅在晚上75毫克)对血小板(抗血小板)作用,并防止血管中的血块。

    阿司匹林should not be used in the patient with bleeding tendency or gastric or duodenal ulcers.

    阿司匹林nowadays used only for as cardio protection and protection of CVA

    Reply
  2. Dr Gurusays

    2011年2月26日上午6:25

    阿司匹林is not a “it acts as a blood thining agent.” It is nothing to do with the blood thickness or viscosity or osmolality. It is act against platelet and inactivate them irreversibly. Thats why you will be asked to stop use aspirin before a major surgery!!

    Reply

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