Omeprazole (Prilosec)vs Prevacid
Omeprazole and Prevacid are two drugs coming under the drug class category of proton pump inhibitors. Proton pumps are situated in mitochondrial membranes, which mean they are in all most all cells. The importance of these drugs is that they selectively inhibit proton pumps in the stomach lining. The mechanism of action is to inhibit H+/K+ ATPase enzyme selectively in gastric parietal cells. In the sense of organic chemistry, both these drugs are benzimidazoles containing substituted benzene ring and imidazole ring.
Omeprazole
Omeprazole is also known by the trade namesPrilosecandZegerid。It is a proton pump inhibitor. This drug is prescribed to treat complications related to excessive acid secretion in the stomach such as damage to the esophagus and gastroesophageal reflux disease (GERD). This drug cannot render immediate relief from heartburns. The tablet should be taken 30 minutes before meals. The pill should be swallowed as a whole without chewing because it may damage the coating which is designed to protect the stomach. Granular suspension should be taken only with apple juice. Sometimes the granular suspension is delivered through nasogastric feeding tube.
There are a number of harmful effects of the drug. Animal studies have shown chronic usage may cause stomach cancers although it is not confirmed with humans up to the date. Tendency to increase bone fracture in hips, wrists, and spine is also found through clinical studies. Long term usage has shown to decrease the Vitamin B12 absorption and, therefore, cause B12 deficiency. Apart from all the harmful effects the drug also has various side effects associated. Uneven and fast heart rate, muscle weakness, diarrhea, coughing and choking, headache, and troubles in memory are some of the serious side effects. In addition weight change, stomach pain, insomnia is also experienced.
Omeprazole should not be taken if one is allergic to the drug. It should not be taken while under medication of other benzimidazole drugs. If a person is taking HIV AIDS medicine, ampicillin, blood thinner, water pills, iron tablets, diabetes medicine it is important to seek medical advice before taking Omeprazole.
prevacid
prevacidis also known by the generic namelansoprazole。该药物用于与胃中过度酸分泌和诸如Zollinger- Ellison综合征等疾病的相同并发症。prevacid和Omeprazole具有很多相似之处,但可以作为与抗生素的结合给出。除了在奥美拉唑下陈述的局限性外,如果患有肝病或血液中镁水平低的人使用prevAcid的使用受到限制。如果一个人在服用prevacid时要服用甲氯富酸盐(甲壳虫),那么最好在进气口之间给出30分钟的差距,因为甲甘蓝使得很难被吸收。prevacid的每日剂量为30mg,大于奥美拉唑剂量20mg。增加骨折的趋势保持不变,但尚未确认维生素B12吸收的降低。其余细节,例如副作用,过量效应非常相似。
奥美拉唑有什么区别(Prilosec)和prevacid?
• Omeprazole is available with or without a prescription, but Prevacid requires a prescription.
• Daily dose of Omeprazole is 20mg, but daily dose of Prevacid is 30mg.
• Omeprazole is less expensive than Prevacid.
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