Difference Between Gene Therapy and Immunotherapy

Thekey differencebetween gene therapy and immunotherapy is that the基因疗法涉及生物体的遗传成分作为治疗策略的改变，而免疫疗法涉及治疗immune systemby administering immune cells as a treatment.

世界上有许多不同的治疗方法。目前，治疗程序更加集中于个性化医学。在本次比赛中，研究人员和医生赞成更具体和可靠的治疗方法。因此，必须将新型技术纳入治疗程序的设计。基因治疗和免疫疗法是疾病治疗中使用的两种此类特定技术。

内容

1.Overview and Key Difference
2.什么是基因疗法
3.What is Immunotherapy
4.Similarities Between Gene Therapy and Immunotherapy
5.Side by Side Comparison – Gene Therapy vs Immunotherapy in Tabular Form
6。概括

什么是基因疗法？

Gene therapy is a form of therapy that alters the genetic component of a person as a method of treatment. Hence, in gene therapy, thegenethat is responsible for the disease or the disorder is altered or inactivated in order to get rid of that particular disease. Though, this is a very specific treatment method, there are a lot of ethical considerations behind the treatment process. Not only that, there are side effects of this method that vary widely. Furthermore, the prediction of the side effects of gene therapy is also a difficult process.

进行基因疗法有三种主要方法。首先，突变的基因或疾病基因可以用同一基因的健康副本代替。在这种情况下，应首先分析突变，并且对基因突变的早期检测非常重要。其次，可以通过沉默的基因使突变或患病基因被灭活。第三，基因疗法可用于向患者引入新基因。现在，这个新基因将负责产生一种新的治疗蛋白，从而治愈该疾病。

通常，兼容的载体涉及最大的基因治疗程序，以将感兴趣的基因携带到宿主生物体。通常，静脉注射方法用于将矢量施用到单个细胞。如果基因疗法成功，将在所需的细胞类型中产生基因产物。因此，基因治疗的成功取决于基因产物的表达。

什么是免疫疗法？

免疫疗法是一种治疗患者免疫系统的治疗方法。这是一种新的治疗方法，并且在癌症治疗中广泛使用。免疫疗法涉及给药的免疫细胞，例如T cells和单克隆抗体给病人。因此，给药这些免疫细胞可以诱导一个人的免疫力。因此，患者从受损的免疫状况到正常状态克服了。

Method of Treatment

Immunotherapy is a specific method of treatment and its accuracy in treatment is very high. Therefore. the main disadvantage of using immunotherapy is the increased risk of autoimmune diseases. Due to this reason, the health professionals should analyse the dosage, pathway of administering, and the side effects of the immunotherapeutic agent well before administering the agent to the patient.

因此，免疫疗法通过增强宿主的免疫力成功地恢复了一个人的免疫力，这将使宿主能够抵抗疾病的疾病。在癌症的情况下，大多数癌症患者免疫受到损害。但是，通过使用免疫治疗剂治疗，很容易恢复癌症患者的免疫力水平。一旦免疫水平上升，最终通过控制癌症就开始死亡。

除了管理免疫细胞,有re other ways of doing immunotherapy, such as the administration of antibodies. In particular, the administering antibodies via intravenous vaccinations is a common immunotherapeutic method. The antibodies will then act against their specific antigens and destroy the pathogen. Use of modified T cells is the second way. Consequently, we can modify T cells by adding specific receptors on to its surface to identify various specific foreign molecules or chemicals. These modified T cells when administered, will target the specific foreign body and destroy it.

What are the Similarities Between Gene Therapy and Immunotherapy?

• 基因治疗和免疫疗法是特定且可靠的治疗程序。
• Both are treatments in cancer treatment.
• Also, alministration of both therapies are intravenous.
• 此外，这些方法需要在给药之前进行高端研究和分析。
• 两种类型都涉及新技术。

What is the Difference Between Gene Therapy and Immunotherapy?

世界上有一些进步和新颖的技术来治疗疾病。其中，基因疗法和免疫疗法是两种不同的程序。基因疗法和免疫疗法之间的关键区别在于，基因疗法涉及患者遗传物质的改变，而免疫疗法涉及免疫细胞，抗体等给药以诱导患者的免疫系统。

Moreover, side effects due to each therapy is an important difference between gene therapy and immunotherapy. The below infographic provides further information on the difference between gene therapy and immunotherapy.

摘要 - 基因治疗与免疫疗法

Gene therapy and immunotherapy are the two main techniques useful in cancer therapy. Gene therapy is the method that alters the genetic composition of the patient as a treatment method. In contrast, immunotherapy is the technique that treats the immune cells. As a result, it enhances the activity of the immune system. Both the techniques are highly specific. Even though the techniques are reliable, the usage of these is minimal in the world. This is due to the highly variable side effects of the treatment procedures. Hence, this is the difference between gene therapy and immunotherapy.

Reference:

1.Rangel-Sosa, Martha Montserrat, et al. “Immunotherapy and Gene Therapy as Novel Treatments for Cancer.” Colombia Médica : CM, Universidad Del Valle, 30 Sept. 2017.Available here
2.“Understanding Immunotherapy.” Cancer.Net, 1 June 2018.Available here
3.“What Is Gene Therapy? – Genetics Home Reference – NIH.” U.S. National Library of Medicine, National Institutes of Health.Available here

Image Courtesy:

1.”39151355192″ byThe U.S. Food and Drug Administration(U.S. Government Works)viaFlickr
2.”11 Hegasy CTLA4 PD1 Immunotherapy”By Guido4 – Own work,(CC BY-SA 3.0)viaCommons Wikimedia