Difference Between Hyperplasia and Neoplasia

Thekey differencebetween hyperplasia and neoplasia is that the增生是一种生理反应t(正常)o a stimulus that leads to normal cell proliferation and enlargement of a tissue while neoplasia is an abnormal cell proliferation in a non-physiological manner, which is unresponsive to a stimulus.

Multicellular organismsare more complex and competent than unicellular organisms. They have different specialized cells, tissues and organs hence, they are able more fit to survive in the environment. However,cell divisionis a highly and tightly regulated process in multicellular organisms. Cells divide at the right time and at a right rate. Sometimes normal cell proliferation can go wrong and result in abnormal cell growth as well. As a result, it can lead to an unwanted cell mass or atumour. Hyperplasia and neoplasia are two types of cell proliferation processes.

内容

1.Overview and Key Difference
2.What is Hyperplasia
3.What is Neoplasia
4.Similarities Between Hyperplasia and Neoplasia
5.并排比较 - 表格形式的增生与肿瘤
6。概括

什么是增生？

Hyperplasia is a type of cell proliferation that leads to an increase in the size of tissue. As a result of it, gross enlargement of an organ can be seen. However, this cell proliferation occurs under the normal conditions. It should not be confused with the benign neoplasia or a benign tumour. But cells appear normal, and this cell proliferation is a common preneoplastic response to a stimulus. When the stimulus stops, the cell proliferation can be stopped. Hence, it is reversible. Sometimes, hyperplasia is responsible for the increase of the cell size as well. But hyperplasia mainly involves increasing the number of cells in a tissue.

由于原因不同，可能会发生增生。这是一个在特定组织中发生的无害过程。由于增生，在刺激反应时可能会发生乳腺细胞中分泌乳腺细胞的生长和繁殖。怀孕。这是一个正常的过程。此外，皮肤表皮基底层的细胞增殖取代了皮肤损失，并且由于增生而发生。

What is Neoplasia?

Cell division is a normal yet a highly regulated process. However, things can go wrong in the regulation of cell division. Neoplasia is such a situation where abnormal cell proliferation occurs in a non –physiological manner unresponsive to a stimulus. It is a new growth that occurred due to an error in the cell division process. Cells divide fast, and it causes compression of neighbouring tissues since it occurs without coordinating with them. So it is a harmful process.

Even though the factor that caused the abnormal cell proliferation stops, it continues the cell proliferation. Hence it is not reversible. As an example, UV light can change a skin cell, and that particular cell may divide uncontrollably until it becomes a skin tumour even though the UV light has gone. Neoplasia can be benign or malignant. If the new growth or tumour can invade other surrounding tissues and spread, it is a malignant type. Cancer is a malignant type of neoplasia. Malignant neoplasm is another word for cancers. In benign neoplasia, cells are well differentiating, not invading the surrounding tissues and slowly growing. However, in malignant neoplasia, cells are poorly differentiating, invading the surrounding tissues and fast growing.

What are the Similarities Between Hyperplasia and Neoplasia?

• 增生和肿瘤是细胞增殖过程。
• Both make the enlargement of tissues to happen.

What is the Difference Between Hyperplasia and Neoplasia?

增生和肿瘤是两个细胞增殖过程。增生发生在正常情况下，而肿瘤却没有。因此，瘤形成，大多数时候都是有害的，而增生一直没有有害。当新生长侵入并扩散到其他组织时，肿瘤可导致癌症。以下信息图介绍了有关表格形式增生和肿瘤之间差异的更多详细信息。

摘要 - 增生与肿瘤

增生是一种细胞增殖，作为对刺激的反应。因此，在正常条件下会导致组织或器官的扩大。另一方面，肿瘤是一种异常的新生长，可以是良性或恶性的。细胞增殖在肿瘤中不可逆，而在增生中则是可逆的。这是增生和肿瘤之间的差异。

Reference:

1. Study.com, Study.com.Available here
2.“Hyperplasia.” Egyptian Journal of Medical Human Genetics, Elsevier.Available here

Image Courtesy:

1. Schwarzemelancholie（Talk）的“增生与肥大” - 自己的作品(CC BY-SA 3.0)viaCommons Wikimedia
2.”Intratubular germ cell neoplasia – high mag” By Nephron – Own work,(CC BY-SA 3.0)viaCommons Wikimedia